10 completed, 5 unknown, 3 recruiting, 2 not yet recruiting. 8 Phase 2, 5 Not applicable, 3 Phase 1, 2 Phase 3.
Follow Lung Cancer, Small Cell: new trials by email Literature Review of Lung Cancer, Small Cell trials Research Report on Lung Cancer, Small Cell
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Engagement of Veterans With Lung Cancer Lay Health Worker (LHW) Planning, Usual Care Group - Lung Cancer (NSCLC), Lung Adenocarcinoma | Not applicable | Recruiting | Palo Alto Veterans Institute for Research | 194 | 2026-02-27 | 2026-03-03 |
| Hypofractionated Radiotherapy Followed by Chemo-immunotherapy Induction Therapy Adebrelimab, EC/EP, SBRT - Lung Cancer, Small Cell, Limited-stage Small Cell Lung Cancer (LS-SCLC) | Phase 2 | Not yet recruiting | Tianjin Medical University Cancer Institute and Hospital | 30 | 2025-04-01 | 2025-04-25 |
| The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled Trial nCLE-NB-rEBUS-forcep biopsy, nCLE-NB-rEBUS-TBCB, NB-rEBUS-forcep biopsy - Lung Cancer, Non-Small Cell, Lung Cancer, Small Cell | Not applicable | Not yet recruiting | China-Japan Friendship Hospital | 1040 | 2025-01-01 | 2024-12-18 |
| Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin Chemotherapy （Etoposide and Carboplatin）, Immunotherapy （Envafolimab）, Trilaciclib - Lung Cancer, Small Cell | Phase 2 | Recruiting | Shanghai Chest Hospital | 52 | 2024-10-13 | 2024-11-21 |
| Implementation of Lung Cancer Screening in the First Line Zone of ZORA (Flanders), Using a Low Dose CT-scan Low-dose CT scan, Smoking Cessation - Lung Cancer, Nonsmall Cell, Lung Cancer | Not applicable | Unknown | University Hospital, Antwerp | 700 | 2024-09-01 | 2024-03-05 |
| A Study on the Efficacy of Atezolizumab Combined with Chemotherapy Atezolizumab, Etoposide, Carboplatin - Lung Cancer, Small Cell | Recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 1430 | 2024-08-28 | 2025-01-17 | |
| Pulmonary Rehabılıtatıon Wıth Non-Small Lung Cancer Pulmonary Rehabilitation - Lung Cancer, Lung Cancer, Small Cell | Not applicable | Unknown | Hasan Kalyoncu University | 11 | 2022-05-02 | 2022-04-11 |
| A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Sitravatinib as Maintenance Therapy for ES-SCLC Tislelizumab, Sitravatinib - Lung Cancer, Small Cell | Phase 2 | Unknown | Zhejiang Cancer Hospital | 21 | 2022-03-17 | 2023-09-26 |
| Trial of NanoPac Intratumoral Injection in Lung Cancer NanoPac (sterile nanoparticulate paclitaxel) Powder for Suspension - Lung Cancer, Nonsmall Cell, Lung Cancer | Phase 2 | Completed | NanOlogy, LLC | 18 | 2021-04-14 | 2025-05-23 |
| CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors CT-0508, Pembrolizumab - HER2-positive, Adenocarcinoma | Phase 1 | Unknown | Carisma Therapeutics Inc | 48 | 2021-02-02 | 2024-12-18 |
| NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer Nutritional Counseling, Medically Tailored Meals (MTMs), Nutrition Prescription - Lung Cancer, Small Cell, Lung Cancer Metastatic | Not applicable | Active not recruiting | Tufts University | 299 | 2020-11-24 | 2025-09-30 |
| Feasibility of Wearable Activity Trackers for Detection of TOXicity in People Receiving Systemic Anticancer Treatment Wearable activity tracker - FitBit - Lung Cancer, Small Cell, Pancreatic Cancer | Unknown | Royal Marsden NHS Foundation Trust | 50 | 2020-07-01 | 2020-06-22 | |
| Lung Cancer Screening Using DNA Methylation Changes in Circulated Tumor and PBMC DNA Lung Cancer, Lung Cancer, Nonsmall Cell | Terminated | HKGepitherapeutics | 81 | 2018-07-01 | 2023-12-22 | |
| A Study to Evaluate Pazopanib in Comparison to Pemetrexed in Maintenance Setting in Non-progressing Subjects With Metastatic Stage IVA and IVB Non-squamous Non-small Cell Lung Cancer (NSCLC) Population pazopanib, pemetrexed - Lung Cancer, Small Cell | Phase 2 | Terminated | GlaxoSmithKline | 20 | 2011-02-01 | 2014-10-27 |
| Regulatory Hycamtin(Oral) PMS Topotecan - Lung Cancer, Small Cell | Completed | GlaxoSmithKline | 92 | 2010-10-01 | 2015-04-15 | |
| SCOT Registry: Small Cell Lung Cancer Treatment and Outcome HYCAMTIN - Lung Cancer, Small Cell | Completed | GlaxoSmithKline | 500 | 2009-11-01 | 2014-02-03 | |
| Study of Oral Topotecan With Bevacizumab for Recurrent Small Cell Lung Cancer Oral Hycamtin (topotecan) Capsules + IV Avastin (bevacizumab) - Recurrent Small-cell Lung Cancer (SCLC), Lung Cancer, Small Cell | Phase 2 | Completed | GlaxoSmithKline | 50 | 2008-07-01 | 2012-03-27 |
| First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin topotecan, carboplatin - Lung Cancer, Small Cell | Phase 2 | Completed | GlaxoSmithKline | 33 | 2005-06-01 | 2015-05-07 |
| A Study To Determine If Two Different Versions Of Topotecan Have The Same Potency In Patients With Advanced Solid Tumors topotecan - Lung Cancer, Small Cell | Phase 1 | Completed | GlaxoSmithKline | 107 | 2004-10-04 | 2017-11-14 |
| The Study Of An Oral Drug Called A Radiation Sensitizer In Patients With Newly Diagnosed Small Cell Lung Cancer (SCLC) topotecan - Lung Cancer, Small Cell, Small Cell Lung Cancer | Phase 2 | Completed | GlaxoSmithKline | 60 | 2002-08-01 | 2017-05-31 |
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Small Cell Lung Carcinoma (23) · Carcinoma, Non-Small-Cell Lung (9) · Lung Neoplasms (8) · Neoplasms (2) · Pancreatic Neoplasms (2) · Stomach Neoplasms (2) · Adenocarcinoma (1) · Adenocarcinoma of Lung (1) · Bile Duct Neoplasms (1) · Biliary Tract Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Ductal (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Ovarian Epithelial (1) · Carcinoma, Small Cell (1)
Bronchial Neoplasms (23) · Carcinoma, Bronchogenic (23) · Lung Diseases (23) · Neoplasms by Site (23) · Respiratory Tract Diseases (23) · Respiratory Tract Neoplasms (23) · Thoracic Neoplasms (23) · Neoplasms (21) · Lung Neoplasms (15) · Carcinoma (2) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2) · Gastrointestinal Diseases (2)
Topotecan (8) · Carboplatin (3) · Bevacizumab (1) · Capsules (1) · Cisplatin (1) · EC regimen (1) · Etoposide (1) · Nutrition Assessment (1) · Paclitaxel (1) · Pemetrexed (1) · Powders (1) · Suspensions (1) · atezolizumab (1) · envafolimab (1) · pazopanib (1)
GlaxoSmithKline (10) · Carisma Therapeutics Inc (1) · China-Japan Friendship Hospital (1) · HKGepitherapeutics (1) · Hasan Kalyoncu University (1) · NanOlogy, LLC (1) · Palo Alto Veterans Institute for Research (1) · Royal Marsden NHS Foundation Trust (1) · Shanghai Chest Hospital (1) · Shanghai Pulmonary Hospital, Shanghai, China (1) · Tianjin Medical University Cancer Institute and Hospital (1) · Tufts University (1) · University Hospital, Antwerp (1) · Zhejiang Cancer Hospital (1)
United States (10) · China (4) · Netherlands (3) · Austria (2) · Germany (2) · Hungary (2) · Poland (2) · South Korea (2) · United Kingdom (2) · Belgium (1) · Bulgaria (1) · Canada (1) · Czechia (1) · Estonia (1) · France (1)
Annemiek Snoeckx, MD, PhD (1) · Colleen Spees, PhD, MEd, RD, LD, FAND (1) · FangFang Zhang, MD, PhD (1) · Jeanett Wetzel (1) · Nadia Yousaf (1) · Shelagh Verco, PhD (1)