2 active not recruiting, 2 completed, 2 recruiting. 6 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Active not recruiting 2, Completed 2, Recruiting 2 |
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
Follow Low-grade Glioma: new trials by email Literature Review of Low-grade Glioma trials Research Report on Low-grade Glioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumours Tovorafenib - Low-grade Glioma | Phase 1 | Active not recruiting | Ipsen | 6 | 2026-03-10 | 2026-10-01 |
| A Study of Avutometinib for People With Solid Tumor Cancers Avutometinib - Refractory Cancer, CNS Tumors | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 3 | 2023-10-20 | 2026-11-04 |
| SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma Mirdametinib - Low-Grade Glioma, Recurrent Low-Grade Glioma | Phase 1 / Phase 2 | Recruiting | St. Jude Children's Research Hospital | 132 | 2021-06-21 | 2026-09-11 |
| Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) Everolimus, Trametinib - Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma | Phase 1 | Recruiting | University of California, San Francisco | 50 | 2020-12-09 | 2026-08-18 |
| DAY101 In Gliomas and Other Tumors DAY101 - Low-grade Glioma | Phase 1 | Completed | Karen D. Wright, MD | 44 | 2018-02-27 | 2026-02-19 |
| A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas Mebendazole, Vincristine, Carboplatin - Pilomyxoid Astrocytoma, Pilocytic Astrocytoma | Phase 1 / Phase 2 | Active not recruiting | Julie Krystal | 10 | 2013-10-22 | 2026-08-06 |
Astrocytoma (2) · Glioma (2) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Diffuse Intrinsic Pontine Glioma (1) · Ganglioglioma (1) · Ganglioneuroma (1) · Glioblastoma (1) · Gliosarcoma (1) · Neoplasms (1) · Neoplasms, Neuroepithelial (1) · Neuroblastoma (1) · Neurocytoma (1) · Neurofibroma, Plexiform (1) · Oligodendroglioma (1)
Neoplasms by Histologic Type (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neuroectodermal Tumors (4) · Brain Diseases (3) · Central Nervous System Diseases (3) · Neoplasms (3) · Neoplasms by Site (3) · Neoplasms, Neuroepithelial (3) · Nervous System Diseases (3) · Nervous System Neoplasms (3) · Brain Neoplasms (2) · Central Nervous System Neoplasms (2) · Peripheral Nervous System Neoplasms (2)
tovorafenib (2) · Bevacizumab (1) · Carboplatin (1) · Everolimus (1) · Irinotecan (1) · Mebendazole (1) · Temozolomide (1) · Vincristine (1) · mirdametinib (1) · trametinib (1)
Ipsen (1) · Julie Krystal (1) · Karen D. Wright, MD (1) · Memorial Sloan Kettering Cancer Center (1) · St. Jude Children's Research Hospital (1) · University of California, San Francisco (1)
United States (5) · Japan (1)
Anna Vinitsky, MD, MS (1) · Giles W. Robinson, MD (1) · Julie Krystal, MD (1) · Karen D. Wright, MD (1) · Sabine Mueller (1) · Sameer Farouk Sait, MD (1)
P50CA165962 (1)