Locally Recurrent Laryngeal Squamous Cell Carcinoma: Clinical Trials

2 recruiting. 2 Phase 2.

By phase and status

Phase	Trials	Status
Phase 2	2	Recruiting 2

Follow Locally Recurrent Laryngeal Squamous Cell Carcinoma: new trials by email Literature Review of Locally Recurrent Laryngeal Squamous Cell Carcinoma trials Research Report on Locally Recurrent Laryngeal Squamous Cell Carcinoma

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer Biospecimen Collection, Carboplatin, Cemiplimab - Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8	Phase 2	Recruiting	National Cancer Institute (NCI)	180	2026-04-24	2026-10-14
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate - Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8	Phase 2	Recruiting	National Cancer Institute (NCI)	150	2022-12-06	2026-10-20

Narrower conditions

Carcinoma (2)  ·  Laryngeal Neoplasms (2)  ·  Mouth Neoplasms (2)  ·  Oropharyngeal Neoplasms (2)  ·  Hypopharyngeal Neoplasms (1)  ·  Melanoma (1)  ·  Squamous Cell Carcinoma of Head and Neck (1)

Broader conditions

Head and Neck Neoplasms (2)  ·  Laryngeal Diseases (2)  ·  Mouth Diseases (2)  ·  Neoplasms (2)  ·  Neoplasms by Histologic Type (2)  ·  Neoplasms by Site (2)  ·  Neoplasms, Glandular and Epithelial (2)  ·  Otorhinolaryngologic Diseases (2)  ·  Otorhinolaryngologic Neoplasms (2)  ·  Pharyngeal Diseases (2)  ·  Pharyngeal Neoplasms (2)  ·  Respiratory Tract Diseases (2)  ·  Respiratory Tract Neoplasms (2)  ·  Stomatognathic Diseases (2)  ·  Carcinoma, Squamous Cell (1)

Interventions

Magnetic Resonance Spectroscopy (2)  ·  Specimen Handling (2)  ·  1,2-diaminocyclohexaneplatinum II citrate (1)  ·  Biopsy (1)  ·  Carboplatin (1)  ·  Cisplatin (1)  ·  Nivolumab (1)  ·  Paclitaxel (1)  ·  Platinum (1)  ·  Radiation (1)  ·  Radiotherapy (1)  ·  Taxes (1)  ·  cabozantinib (1)  ·  cemiplimab (1)

Sponsors

National Cancer Institute (NCI) (2)

Countries

United States (2)

Top investigators

Nabil F Saba (1)  ·  Siwen Hu-Lieskovan (1)

NIH funding

U10CA180868 (1), U10CA180888 (1)