9 completed, 4 recruiting, 3 unknown, 2 active not recruiting. 7 Phase 1, 7 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 4, Active not recruiting 2, Recruiting 1 |
| Phase 2 | 7 | Completed 4, Active not recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Infectious Mononucleosis: new trials by email Literature Review of Infectious Mononucleosis trials Research Report on Infectious Mononucleosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection EBV gp350-ferritin vaccine with ALFQ adjuvant, EBV gH/gL/gp42-ferritin nanoparticle vaccine with ALFQ adjuvant - EBV, Epstein-Barr Virus Infection | Phase 1 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 750 | 2025-05-29 | 2026-10-26 |
| Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative Persons Matrix-M1 Adjuvant, EBV gp350-Ferritin Vaccine, Placebo Comparator - Epstein-Barr Virus Infection, Infectious Mononucleosis | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 25 | 2023-09-22 | 2026-04-22 |
| A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Participants mRNA-1195.1, mRNA-1195.2, mRNA-1189 - Epstein-Barr Virus Infection | Phase 1 | Active not recruiting | ModernaTX, Inc. | 482 | 2023-04-05 | 2026-08-11 |
| Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) Diabetes, Chronic Kidney Diseases | Unknown | Willows Health | 2000 | 2023-01-01 | 2022-08-15 | |
| Safety and Immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine in Healthy Adults EBV gp350-Ferritin Vaccine - EBV, Epstein-Barr Virus Infection | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 83 | 2022-03-29 | 2026-08-13 |
| A Risk Stratified Sequential Treatment With Rituximab, Brentuximab Vedotin and Bendamustine (RBvB) Rituximab, Brentuximab Vedotin, Bendamustine - PTLD, Lymphoid Tumor | Phase 2 | Withdrawn | Yale University | 2022-01-01 | 2022-06-23 | |
| A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults mRNA-1189, Placebo - Epstein-Barr Virus Infection | Phase 1 / Phase 2 | Active not recruiting | ModernaTX, Inc. | 867 | 2021-12-28 | 2026-05-06 |
| Occurrence of Antibodies Cross-reacting With Autoantigens in Primary EBV Infection Data collection: Participant characteristics (Illness course, complications of primary EBV infection and provided treatments), Data collection: blood samples (analysed for EBV serology, auto-antibody-testing/biobanking, RNA expression analyses, procalcitonin), Data collection: Patient reported outcome (Fatigue questionnaires) - Epstein-Barr Virus (EBV) Infection | Recruiting | University Hospital, Basel, Switzerland | 80 | 2021-10-15 | 2025-02-25 | |
| HIV Indicator Diseases in Hospital and Primary Care Peer to peer feedback, HIV rapid test - HIV Infections, Primary Health Care | Unknown | Erasmus Medical Center | 1500 | 2020-01-01 | 2022-02-04 | |
| Munich ME/CFS Cohort Study Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3) | Recruiting | Technical University of Munich | 200 | 2019-01-22 | 2023-08-22 | |
| Early Detection of Epstein-Barr Virus Related Disease. Post-transplant Lymphoproliferative Disorder, Mononucleosis | Completed | University of Aarhus | 1527 | 2017-11-01 | 2023-10-31 | |
| Microbiology of Severe Acute Tonsillitis, Peritonsillar Cellulitis, and Infectious Mononucleosis Throat swabbing - Acute Tonsillitis, Peritonsillar Cellulitis | Unknown | Tejs Ehlers Klug | 350 | 2016-06-01 | 2016-03-22 | |
| The Use of Point-of-Care Ultrasound in the Diagnosis of Acute Infectious Mononucleosis in the Emergency Department Point-of-care ultrasound - Infectious Mononucleosis, Splenomegaly | Terminated | Jewish General Hospital | 200 | 2016-04-01 | 2020-10-06 | |
| Study on Infectious Mononucleosis in Munich Infectious Mononucleosis, Epstein-Barr Virus Infections | Completed | Technical University of Munich | 200 | 2016-03-01 | 2024-02-07 | |
| Comparison of Technics for Determination of Epstein-Barr Virus Serological Diagnosis Serological giagnosis - EBV | Completed | Centre Hospitalier Universitaire, Amiens | 91 | 2015-01-01 | 2026-06-16 | |
| Acupuncture for Infectious Mononucleosis Trial traditional Chinese acupuncture, standard medical care - Infectious Mononucleosis | Phase 2 / Phase 3 | Terminated | University of Alberta | 3 | 2008-01-01 | 2022-07-11 |
| Activity of Valomaciclovir in Infectious Mononucleosis Due to Primary Epstein-Barr Virus Infection Valomaciclovir, placebo - Infectious Mononucleosis | Phase 1 / Phase 2 | Completed | University of Minnesota | 23 | 2007-11-01 | 2017-03-22 |
| Controlled Trial of Valacyclovir in Infectious Mononucleosis valacyclovir - Infectious Mononucleosis | Phase 1 / Phase 2 | Completed | University of Minnesota | 20 | 2004-02-01 | 2011-10-27 |
| Genetic Studies of Chronic Active Epstein-Barr Disease Chronic Active Epstein-Barr Virus | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 300 | 2002-04-16 | 2026-10-29 | |
| Genetic Studies of X-linked Lymphoproliferative Disease X-Linked Lymphoproliferative Disease, Lymphoproliferative Disease | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 12 | 1996-05-22 | 2017-07-02 |
Showing 20 of 21. Sign in to see all of them.
Epstein-Barr Virus Infections (15) · Infections (4) · Acquired Immunodeficiency Syndrome (2) · Fatigue Syndrome, Chronic (2) · HIV Infections (2) · Herpes Simplex (2) · Lymphoproliferative Disorders (2) · Virus Diseases (2) · Alzheimer Disease (1) · Appendicitis (1) · Arthritis (1) · Bronchitis (1) · Bulimia (1) · Candidiasis (1)
DNA Virus Infections (21) · Hematologic Diseases (21) · Hemic and Lymphatic Diseases (21) · Herpesviridae Infections (21) · Immune System Diseases (21) · Immunoproliferative Disorders (21) · Leukocyte Disorders (21) · Lymphatic Diseases (21) · Lymphoproliferative Disorders (19) · Virus Diseases (19) · Infections (17) · Tumor Virus Infections (15) · Epstein-Barr Virus Infections (6) · Pathological Conditions, Signs and Symptoms (5) · Skin and Connective Tissue Diseases (5)
Bendamustine Hydrochloride (1) · Blood Specimen Collection (1) · Brentuximab Vedotin (1) · Matrix-M (1) · Procalcitonin (1) · Rituximab (1) · Valacyclovir (1) · valomaciclovir (1)
National Institute of Allergy and Infectious Diseases (NIAID) (5) · ModernaTX, Inc. (2) · Technical University of Munich (2) · University of Minnesota (2) · Centre Hospitalier Universitaire, Amiens (1) · Erasmus Medical Center (1) · Henogen (1) · Jewish General Hospital (1) · Tejs Ehlers Klug (1) · University Hospital, Basel, Switzerland (1) · University of Aarhus (1) · University of Alberta (1) · Willows Health (1) · Yale University (1)
United States (10) · Canada (2) · Denmark (2) · Germany (2) · Belgium (1) · France (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Jessica R Durkee-Shock, M.D. (3) · Henry H Balfour, MD (2) · Francesa Montanari, MD (1) · Jeffrey I Cohen, M.D. (1) · Lene Ugilt, MD (1) · Michael Osthoff, PD Dr. med. (1) · Philippe B Wilson (1) · Rishabh Prasad (1) · Sandrine Castelain, MD, PhD (1) · Sunita Vohra, MD, MSc (1) · Uta Behrends, Prof. Dr. (1)
PMID 18190254, PMID 31064750, PMID 37683299, PMID 38957951, PMID 39731054, PMID 42311676, PMID 42720126