4288 completed, 448 unknown, 411 terminated, 294 recruiting. 5946 Phase 1, 1387 Phase 2.
Follow Infections: new trials by email Literature Review of Infections trials Research Report on Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma Autologous BAFFR-targeting CAR T Cells, Biospecimen Collection, Bone Marrow Aspiration - Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 16 | 2027-04-17 | 2026-08-11 |
| Phase I Safety Clinical Trial of Anti-CD19 CAR-T Therapy COL01 for the Treatment of Adults With Relapsed or Refractory B-cell Lymphoid Neoplasms: First-in-human Administration, COLIBRI. CAR-T anti-CD19 COL01 - Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia, Lymphoid Malignancies | Phase 1 | Not yet recruiting | GUSTAVO SALGUERO | 12 | 2027-04-01 | 2026-10-20 |
| Safety & Immunogenicity of 426c.Mod.Core-C4b Vaccine With 3M-052-AF+Alum in Infants Perinatally Exposed to HIV But Uninfected 426c.Mod.Core-C4b, 3M-052-AF, Aluminum hydroxide suspension (Alum) - HIV Infections | Phase 1 | Not yet recruiting | HIV Vaccine Trials Network | 22 | 2027-03-30 | 2026-09-18 |
| Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina Faso PfSPZ-LARC2 Vaccine, PfSPZ Challenge, Normal Saline - Malaria (Plasmodium Falciparum) | Phase 1 | Not yet recruiting | Sanaria Inc. | 45 | 2027-03-01 | 2026-07-31 |
| A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV) Treatment metronidazole (MTZ)+ LCFA-01 placebo + LC103 placebo, metronidazole (MTZ)+ LCFA-01 + LC103 placebo, metronidazole (MTZ)+ LC103 + LCFA-01 placebo - Bacterial Vaginosis | Phase 1 | Not yet recruiting | Massachusetts General Hospital | 280 | 2027-02-03 | 2026-10-15 |
| Combining Neo-adjuvant ATR-inhibition With Nodal SBRT for Early-stage Resectable HPV+ OPSCCs ATRN-119, Stereotactic Body Radiation Therapy (SBRT) - HPV Positive Oropharyngeal Squamous Cell Carcinoma, Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Abramson Cancer Center at Penn Medicine | 35 | 2027-01-31 | 2026-10-27 |
| A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose Primary Dosing Series Followed by a Booster Dose at 12 to 15 Months of Age Pn-MAPS30plus, PCV20 - Pneumonia, Bacterial | Phase 1 | Not yet recruiting | GlaxoSmithKline | 60 | 2027-01-25 | 2026-07-16 |
| A Phase 1 Clinical Trial of Adjuvanted Protein-based HCV Vaccine Candidates (HCV Vaccine Trial) AVIHepC1, Normal Saline - Hepatitis C | Phase 1 | Not yet recruiting | University of Alberta | 27 | 2027-01-15 | 2026-09-25 |
| Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene Biopsy Procedure, Biospecimen Collection, Computed Tomography - Burkitt Lymphoma, Double-Expressor Lymphoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 50 | 2027-01-11 | 2026-10-14 |
| Phase I Study of VLPDEN-02 Dengue Vaccine in Healthy Adults VLPDEN-02 1.0 µg (0.25 µg of each VLP) + ALFQ adjuvant, VLPDEN-02 10 µg (2.5 µg of each VLP) + ALFQ adjuvant, VLPDEN-02 100 µg (25 µg of each VLP) + ALFQ adjuvant - Randomised Clinical Trial, Double Blind | Phase 1 | Not yet recruiting | VLP Therapeutics | 42 | 2027-01-04 | 2026-09-21 |
| Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis Hyaluronic Acid mouthwash, Chlorohexidine 0.12% mouthwash - Plaque Induced Gingival Disease | Phase 1 | Not yet recruiting | Cairo University | 24 | 2027-01-01 | 2026-10-13 |
| HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence: Infant Versus Standard Formulation ivermectin infant formula preparation, Standard ivermectin 3mg tablet - Scabies | Phase 1 | Suspended | Murdoch Childrens Research Institute | 52 | 2027-01-01 | 2026-10-09 |
| Precision Modulation of Gut Microbiome Enteropathogen Colonization in Critical Illness Synbiotic, Standard of Care (SOC) - Critical Illness | Phase 1 / Phase 2 | Not yet recruiting | University of Calgary | 64 | 2027-01-01 | 2026-09-10 |
| Evaluation of the Safety and Efficacy of XoGlo Pro, a Placental Mesenchymal Stem Cell-derived Extracellular Vesicles in Treating COVID-19 Symptoms IV infusion using an isolated, placental, mesenchymal stem cell derived EVs, Placebo IV administration - COVID-19 | Phase 1 / Phase 2 | Not yet recruiting | Kimera Labs Inc. | 64 | 2027-01-01 | 2026-06-24 |
| Study Of KITE-753 in R/R B-Cell ALL KITE-753 - B-cell Acute Lymphoblastic Leukemia | Phase 1 | Not yet recruiting | M.D. Anderson Cancer Center | 18 | 2026-12-31 | 2026-09-11 |
| Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa VPM1002 Vaccine, BCG Vaccine, Placebo - Tuberculosis, HIV Infections | Phase 1 / Phase 2 | Withdrawn | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | 2026-12-31 | 2026-08-17 | |
| Taurine Supplementation in Adolescents With Post-COVID Condition Taurine - Long COVID, Post COVID-19 Condition | Phase 1 / Phase 2 | Not yet recruiting | University of Alberta | 30 | 2026-12-30 | 2026-10-16 |
| Phase 1 Trial to Evaluate Safety and Immunogenicity of MVA-BN-EBV in Healthy Young Adults MVA-BN-EBV, Placebo - Epstein Barr Virus (EBV) Infection | Phase 1 | Not yet recruiting | Bavarian Nordic | 15 | 2026-12-15 | 2026-10-22 |
| A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia sonrotoclax, Azacitidine, Inotuzumab ozogamicin - Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia | Phase 1 / Phase 2 | Not yet recruiting | BeOne Medicines | 30 | 2026-12-01 | 2026-10-26 |
| A Study to Describe the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine IN006 in Healthy Adults Bivalent RSV Vaccine (IN006), Placebo - Respiratory Syncytial Virus Infections | Phase 1 | Not yet recruiting | Shenzhen Shenxin Biotechnology Co., Ltd | 200 | 2026-12-01 | 2026-04-13 |
Showing 20 of 5946. Sign in to see all of them.
HIV Infections (998) · COVID-19 (675) · Acquired Immunodeficiency Syndrome (507) · Burkitt Lymphoma (436) · Influenza, Human (395) · Hepatitis C (266) · Malaria (264) · Lymphoma, Large B-Cell, Diffuse (261) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (257) · Lymphoma, Non-Hodgkin (239) · Lymphoma, Follicular (238) · Lymphoma, Mantle-Cell (237) · Leukemia, Lymphocytic, Chronic, B-Cell (216) · Lymphoma, B-Cell, Marginal Zone (209)
Virus Diseases (4056) · RNA Virus Infections (3091) · Communicable Diseases (1866) · Immune System Diseases (1801) · Blood-Borne Infections (1796) · Urogenital Diseases (1536) · Respiratory Tract Diseases (1441) · Genital Diseases (1438) · Sexually Transmitted Diseases (1310) · Sexually Transmitted Diseases, Viral (1306) · Immunologic Deficiency Syndromes (1267) · Respiratory Tract Infections (1262) · Retroviridae Infections (1259) · Lentivirus Infections (1255)
Sodium Chloride (108) · Ritonavir (100) · Saline Solution (97) · Cyclophosphamide (90) · Zidovudine (68) · Influenza Vaccines (55) · Vaccines (51) · dolutegravir (46) · Rituximab (41) · Injections (40) · Tenofovir (40) · Midazolam (38) · Ribavirin (37) · Aluminum Hydroxide (36) · Rifampin (36)
National Institute of Allergy and Infectious Diseases (NIAID) (791) · GlaxoSmithKline (217) · ViiV Healthcare (125) · National Cancer Institute (NCI) (117) · University of Oxford (114) · Merck Sharp & Dohme LLC (99) · Pfizer (89) · U.S. Army Medical Research and Development Command (55) · Bristol-Myers Squibb (54) · Medicines for Malaria Venture (44) · Sanofi Pasteur, a Sanofi Company (39) · Tibotec Pharmaceuticals, Ireland (39) · Gilead Sciences (37) · Baylor College of Medicine (35) · Hoffmann-La Roche (33)
United States (3009) · China (431) · United Kingdom (335) · Australia (254) · Canada (164) · Germany (145) · Belgium (144) · France (133) · South Africa (130) · South Korea (125) · Netherlands (108) · Spain (103) · Brazil (92) · Puerto Rico (91) · Thailand (79)
Anna Durbin, MD (30) · Ruth A. Karron, MD (17) · Helen McShane (16)
PMID 34473343, PMID 40190112, PMID 25820067, PMID 34515338, PMID 41671463, PMID 23349878, PMID 25466778, PMID 34817414, PMID 34843602, PMID 35622074, PMID 35713300, PMID 36435633, PMID 37231296, PMID 39787798, PMID 22288567, PMID 26383952, PMID 26432909, PMID 27568215, PMID 29217375, PMID 31932368, PMID 31986264, PMID 32838558, PMID 34895272, PMID 35769034, PMID 36147329, PMID 37781954, PMID 40245769, PMID 41014333, PMID 16148846, PMID 16220994, PMID 17957238, PMID 18090046, PMID 19118378, PMID 19529780, PMID 19540952, PMID 19949018, PMID 20028764, PMID 20126394, PMID 20629533, PMID 21488067, PMID 21906647, PMID 21975270, PMID 22002018, PMID 22242162, PMID 22306375, PMID 22336878, PMID 22426327, PMID 22542645, PMID 22900504, PMID 22914365
2023 (25), 2015 (23), 2016 (22), 2019 (21), 2009 (20), 2018 (20), 2014 (18), 2017 (18), 2008 (16), P30CA033572 (15), U01CA121947 (11), 2025 (10), U01CA097452 (9), P30CA015083 (8), P30CA015704 (8)