8 terminated. 8 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Terminated 8 |
| Phase 2 | 3 | Terminated 3 |
Follow Hypoglycemia: new trials by email Literature Review of Hypoglycemia trials Research Report on Hypoglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of ZT-01 on Glucagon During Hypoglycemia in Type 1 Diabetes Mellitus ZT-01 low dose, ZT-01 high dose, Placebo - Type 1 Diabetes, Hypoglycemia | Phase 1 | Terminated | Zucara Therapeutics Inc. | 24 | 2021-07-08 | 2023-07-12 |
| Insulin Tolerance Test Study in Patients With Type 1 Diabetes Pitolisant - Type 1 Diabetes, Hypoglycemia | Phase 1 | Terminated | High Point Clinical Trials Center | 5 | 2019-09-15 | 2021-04-02 |
| Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia intra-nasal naloxone, Intra-nasal saline - Hypoglycemia Unawareness, Type 1 Diabetes | Phase 1 / Phase 2 | Terminated | University of Minnesota | 11 | 2016-06-01 | 2023-03-27 |
| CREON for the Treatment of Post-RYGB Hypoglycemia Creon, Diet, Placebo - Hypoglycemia | Phase 1 | Terminated | East Carolina University | 5 | 2014-02-01 | 2023-10-26 |
| Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery Exendin (9-39), Placebo - Hypoglycemia | Phase 1 | Terminated | Tracey McLaughlin | 10 | 2014-02-01 | 2024-12-04 |
| Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia Exendin (9-39), Vehicle - Congenital Hyperinsulinism | Phase 1 / Phase 2 | Terminated | Diva De Leon | 14 | 2009-08-26 | 2020-06-01 |
| Effect of Cinnamon Extract on Insulin Resistance in Polycystic Ovary Syndrome Cinnamon Supplementation, Placebo (wheat flour) - Polycystic Ovary Syndrome, Insulin Resistance | Phase 1 | Terminated | Pennington Biomedical Research Center | 8 | 2009-08-01 | 2021-08-25 |
| Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes Allogeneic islets of Langerhans transplant, Raptiva, Sirolimus - Type 1 Diabetes Mellitus, Hypoglycemia | Phase 1 / Phase 2 | Terminated | University of Minnesota | 23 | 2007-11-01 | 2017-10-25 |
Diabetes Mellitus, Type 1 (4) · Congenital Hyperinsulinism (1) · Diabetes Mellitus (1) · Glucose Metabolism Disorders (1) · Hyperinsulinism (1) · Infant, Newborn, Diseases (1) · Insulin Resistance (1) · Metabolic Diseases (1) · Pancreatic Diseases (1) · Polycystic Ovary Syndrome (1)
Nutritional and Metabolic Diseases (8) · Glucose Metabolism Disorders (7) · Metabolic Diseases (7) · Endocrine System Diseases (5) · Autoimmune Diseases (4) · Immune System Diseases (4) · Diabetes Mellitus (3) · Adnexal Diseases (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Cysts (1) · Digestive System Diseases (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Genital Diseases (1) · Genital Diseases, Female (1)
exendin (9-39) (2) · Antilymphocyte Serum (1) · Diet (1) · Flour (1) · Naloxone (1) · Pancrelipase (1) · Sirolimus (1) · efalizumab (1) · pitolisant (1) · thymoglobulin (1)
University of Minnesota (2) · Diva De Leon (1) · East Carolina University (1) · High Point Clinical Trials Center (1) · Pennington Biomedical Research Center (1) · Tracey McLaughlin (1) · Zucara Therapeutics Inc. (1)
United States (6) · Canada (1)
Amir Moheet, MD (1) · Bernhard J. Hering, M.D. (1) · Colleen Craig, M.D. (1) · Diva D De Leon, MD MSCE (1) · Leanne Redman, PhD (1) · Melanie Fein, MD (1) · Moahad S Dar, MD (1) · Richard Liggins, PhD (1)