6 completed. 6 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 6 |
Follow Hemolysis: new trials by email Literature Review of Hemolysis trials Research Report on Hemolysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Primaquine Enantiomers in G6PD Deficient Human Volunteers RPQ, SPQ, Placebo - G6PD Deficiency | Phase 1 | Completed | University of Mississippi, Oxford | 18 | 2020-09-01 | 2024-11-21 |
| Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen RPQ, SPQ, Primaquine Phosphate - Malaria, Glucose 6 Phosphate Dehydrogenase Deficiency | Phase 1 | Completed | University of Mississippi, Oxford | 36 | 2018-08-17 | 2019-05-14 |
| Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects. Pegcetacoplan - Paroxysmal Nocturnal Hemoglobinuria | Phase 1 | Completed | Apellis Pharmaceuticals, Inc. | 23 | 2015-12-01 | 2021-01-11 |
| A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH Pegcetacoplan - Paroxysmal Nocturnal Hemoglobinuria (PNH) | Phase 1 | Completed | Apellis Pharmaceuticals, Inc. | 9 | 2015-02-23 | 2021-01-08 |
| Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders Sodium Nitrite Cream - Sickle Cell Anemia, Sickle Cell Disease | Phase 1 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 28 | 2011-03-15 | 2018-10-22 |
| Probiotic Ingestion and Isoagglutinin Titers Probiotic Supplement - Isoagglutinin-Mediated Hemolysis, Probiotic Toxicity | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 36 | 2009-04-28 | 2017-10-06 |
Anemia (3) · Glucosephosphate Dehydrogenase Deficiency (2) · Hematologic Diseases (2) · Hemoglobinuria (2) · Hemoglobinuria, Paroxysmal (2) · Malaria (2) · Anemia, Sickle Cell (1) · Leg Ulcer (1) · Thalassemia (1)
Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Anemia, Hemolytic (5) · Hemic and Lymphatic Diseases (5) · Anemia, Hemolytic, Congenital (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Hematologic Diseases (3) · Anemia (2) · Bone Marrow Diseases (2) · Carbohydrate Metabolism, Inborn Errors (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Infections (2) · Male Urogenital Diseases (2)
pegcetacoplan (2) · Primaquine (1)
Apellis Pharmaceuticals, Inc. (2) · University of Mississippi, Oxford (2) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Institutes of Health Clinical Center (CC) (1)
United States (5) · Hong Kong (1) · Malaysia (1) · New Zealand (1) · Thailand (1)
Federico Grossi, MD, PhD (2) · Larry Walker, Ph.D. (1) · Larry Walker, Phd (1) · Matthew M Hsieh, M.D. (1) · Susan F Leitman, M.D. (1)