36 completed, 19 recruiting, 13 active not recruiting, 5 terminated. 31 Not applicable, 20 Phase 2, 14 Phase 1, 3 Phase 3, 1 Early Phase 1.
Follow Head and Neck Carcinoma: new trials by email Literature Review of Head and Neck Carcinoma trials Research Report on Head and Neck Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A New Way to Share Radiation Therapy Plans Between Doctors, CORRECT Trial Training and Education, Communication Intervention, Survey Administration - Lung Carcinoma, Head and Neck Carcinoma | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 194 | 2026-11-01 | 2026-10-23 |
| Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck Cancers Electronic Health Record Review, Fentanyl, Laryngoscopy - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Phase 4 | Recruiting | OHSU Knight Cancer Institute | 58 | 2026-09-22 | 2026-10-05 |
| The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas Cancer Therapeutic Procedure, Questionnaire Administration - Amyloidosis, Basal Cell Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 27 | 2025-12-18 | 2026-09-30 |
| Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer Tongue-out radiation therapy (TORT) - Head and Neck Carcinoma | Not applicable | Recruiting | Yvonne Mowery | 35 | 2025-11-23 | 2025-12-17 |
| A Financial Intervention (Financial Compass) to Identify and Address Financial Hardship Among Head and Neck Cancer Patients, Financial Compass Trial Best Practice, Discussion, Financial Navigation - Head and Neck Carcinoma | Not applicable | Recruiting | Roswell Park Cancer Institute | 50 | 2025-09-23 | 2026-06-08 |
| Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers Computed Tomography, Fludeoxyglucose F-18, Gallium Ga 68 FAPi-46 - Anal Carcinoma, Bladder Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-08-01 | 2026-10-20 |
| Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer Metronidazole, Chlorhexidine - Oral Squamous Cell Carcinoma, Oral Cancer | Phase 2 | Recruiting | Case Comprehensive Cancer Center | 30 | 2025-07-22 | 2026-08-06 |
| Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers Interview, Medical Device Usage and Evaluation, Questionnaire Administration - Head and Neck Carcinoma | Not applicable | Recruiting | City of Hope Medical Center | 40 | 2025-06-25 | 2025-11-10 |
| Accelerator-based BNCT (Boron Neutron Capture Therapy) for Head and Neck Carcinoma. L-Boronophenylalanine intravenous administration - Head and Neck Carcinoma | Phase 1 | Recruiting | Neutron Therapeutics, LLC | 10 | 2025-05-08 | 2025-07-10 |
| Heavy Strength Training in Head and Neck Cancer Survivors Experimental - Head and Neck Neoplasms, Head and Neck Cancer | Phase 2 | Completed | University of Alberta | 37 | 2025-02-17 | 2026-08-12 |
| Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal) Personalized ultrafractionated stereotactic adaptive radiotherapy, Volume Modulated Arc Therapy, Computed Tomography - Head and Neck Carcinoma, Localized Head and Neck Carcinoma | Not applicable | Recruiting | Jonsson Comprehensive Cancer Center | 43 | 2024-10-25 | 2026-02-05 |
| Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients Surveys, Saliva Collection, Intra-oral photographs - Head and Neck Cancer, Head and Neck Carcinoma | Not applicable | Active not recruiting | University of California, San Francisco | 43 | 2024-10-01 | 2026-06-01 |
| Defining Musical Toxicity and Its Effect on Patient Well-being Non-Interventional Study - Breast Carcinoma, Esophageal Carcinoma | Withdrawn | Mayo Clinic | 2024-08-15 | 2025-06-04 | ||
| An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence Non-Interventional Study - Head and Neck Carcinoma | Recruiting | University of Southern California | 50 | 2024-03-25 | 2026-04-28 | |
| Optimization of Communication Between Surgery and Pathology visual description of frozen section results during surgery - Head and Neck Carcinoma, Frozen Section Management | Not applicable | Completed | Heidelberg University | 155 | 2024-03-05 | 2026-01-30 |
| An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery Electronic Health Record Review, Exercise Intervention, Medical Device Usage and Evaluation - Head and Neck Carcinoma | Not applicable | Completed | OHSU Knight Cancer Institute | 52 | 2024-02-01 | 2025-12-12 |
| StrataXRT for the Prevention and Treatment of Radiation Dermatitis in Breast Cancer or Head and Neck Cancer Patients Calendula Ointment, Petrolatum-Mineral Oil-Lanolin-Ceresin Ointment, Polyethylene Glycol Hydrogel - Breast Carcinoma, Head and Neck Carcinoma | Not applicable | Withdrawn | OHSU Knight Cancer Institute | 2024-01-01 | 2024-05-06 | |
| Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy Spot Delete - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Not applicable | Recruiting | Covenant Health Cancer Center | 100 | 2023-12-13 | 2025-04-08 |
| Repeatability and Reproducibility of the ADC Map in Head and Neck Cancer. Prospective Multicenter Study Head and Neck Carcinoma | Completed | Regina Elena Cancer Institute | 58 | 2023-09-11 | 2026-06-05 | |
| Therapeutic Vaccine in Patients With Human Papillomavirus HPV-positive Oropharyngeal Cancer HPVDC injection level dose 1, placebo injection level dose 1, HPVDC injection level dose 2 - Head and Neck Carcinoma, Adult Disease | Phase 1 / Phase 2 | Completed | Gustave Roussy, Cancer Campus, Grand Paris | 24 | 2023-07-31 | 2026-09-18 |
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Lung Neoplasms (17) · Breast Neoplasms (16) · Squamous Cell Carcinoma of Head and Neck (16) · Head and Neck Neoplasms (15) · Esophageal Neoplasms (9) · Mouth Neoplasms (8) · Ovarian Neoplasms (8) · Pancreatic Neoplasms (8) · Stomach Neoplasms (7) · Carcinoma, Renal Cell (6) · Laryngeal Neoplasms (6) · Melanoma (6) · Oropharyngeal Neoplasms (6) · Prostatic Neoplasms (6) · Urinary Bladder Neoplasms (6)
Neoplasms by Site (44) · Neoplasms (43) · Neoplasms by Histologic Type (29) · Neoplasms, Glandular and Epithelial (27) · Respiratory Tract Diseases (25) · Respiratory Tract Neoplasms (25) · Carcinoma (22) · Lung Diseases (20) · Thoracic Neoplasms (20) · Skin Diseases (18) · Skin and Connective Tissue Diseases (18) · Breast Diseases (16) · Carcinoma, Squamous Cell (16) · Head and Neck Neoplasms (16) · Digestive System Diseases (15)
Practice Guidelines as Topic (8) · Standard of Care (8) · Magnetic Resonance Spectroscopy (6) · X-Rays (4) · Cetuximab (3) · Interviews as Topic (3) · Radiotherapy, Intensity-Modulated (3) · Specimen Handling (3) · pembrolizumab (3) · Behavior Therapy (2) · FAPI-46 (2) · Fluorodeoxyglucose F18 (2) · Monitoring, Physiologic (2) · Nivolumab (2) · Radiation (2)
M.D. Anderson Cancer Center (11) · Mayo Clinic (8) · OHSU Knight Cancer Institute (7) · Jonsson Comprehensive Cancer Center (4) · Roswell Park Cancer Institute (3) · City of Hope Medical Center (2) · Maastricht Radiation Oncology (2) · Memorial Sloan Kettering Cancer Center (2) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (2) · Stanford University (2) · Thomas Jefferson University (2) · Alliance for Clinical Trials in Oncology (1) · Assuntina G. Sacco, MD (1) · AstraZeneca (1) · British Columbia Cancer Agency (1)
United States (65) · Canada (3) · France (3) · China (2) · Egypt (2) · Italy (2) · Netherlands (2) · Puerto Rico (2) · Austria (1) · Estonia (1) · Finland (1) · Germany (1) · Guam (1) · India (1) · Pakistan (1)
Ryan J Li (2) · Steven J Frank (2) · Abie Mendelsohn (1) · Albert Y Han, MD (1) · Andre Dekker, Prof.Dr.Ir. (1) · Angel Estrada, PhD (1) · Anna Lee (1) · Anurag K Singh (1) · Anurag Singh (1) · Ari Rosenberg, MD (1) · Arnaud Bewley, MD (1) · Arya Amini (1) · Beth Beadle (1)
PMID 18397244, PMID 19398490, PMID 19653045, PMID 20837830, PMID 23129676, PMID 25117521, PMID 25214508, PMID 26586415, PMID 27992617, PMID 32463741, PMID 33048619, PMID 33198942, PMID 34348950, PMID 34749008, PMID 35133871, PMID 35138919, PMID 35500434, PMID 35676062, PMID 35771552, PMID 36351402, PMID 36512649, PMID 37053535, PMID 37322121, PMID 37934000, PMID 38591867, PMID 39666929, PMID 39693587, PMID 39709372, PMID 39913160, PMID 39913886, PMID 40865033, PMID 40905435, PMID 40927950, PMID 41066729, PMID 41101974, PMID 41396606, PMID 41499420, PMID 8450679, PMID 8769910, PMID 9311098
P30CA016672 (3), P30CA033572 (2), P30CA012197 (1), P30CA013330 (1), P30CA014089 (1), P30CA016056 (1), P30CA023074 (1), P30CA069533 (1), R01CA204636 (1), R01CA247307 (1), R21CA226200 (1), U10CA180820 (1), U24CA196172 (1), U34CA297499 (1), UG1CA189823 (1)