11 completed, 3 not yet recruiting, 1 active not recruiting, 1 recruiting. 14 Not applicable, 2 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 11, Not yet recruiting 2, Unknown 1 |
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Fine Lines: new trials by email Literature Review of Fine Lines trials Research Report on Fine Lines
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assess Injectable Hyaluronic Acid Gel for the Treatment of Volume Loss, Skin Laxity and Fine Lines Obagi® Saypha® MagIQ™ Injectable Hyaluronic Acid - Fine Lines, Wrinkle | Phase 4 | Not yet recruiting | Goldman, Butterwick, Fitzpatrick and Groff | 100 | 2026-03-01 | 2026-02-19 |
| Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging. Active cream - Skin, Skin Ageing | Not applicable | Not yet recruiting | AB Biotics, SA | 45 | 2026-02-01 | 2026-01-15 |
| Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects. Standardized Saffron Extract (Crocus Sativus L) 10 mg Capsule, Placebo (capsules containing Maltodextrin, Calcium carbonate, Sunset yellow, Maize starch, Mg Stearate, Talc) - Wrinkles, Fine Lines | Not applicable | Not yet recruiting | NovoBliss Research Pvt Ltd | 50 | 2026-01-01 | 2026-01-07 |
| A Clinical Study to Test the Safety and Effectiveness of Pinorox® for Improving Visible Signs of Facial Aging Such as Wrinkles, Fine Lines, and Dark Spots. Topical Cream containing 0.1% Pinorox®, Topical Cream containing 1% Pinorox®, Placebo (Base Cream) - Fine Lines, Wrinkles | Not applicable | Completed | NovoBliss Research Pvt Ltd | 81 | 2025-10-16 | 2026-08-05 |
| Autologous Adipose Cells Therapy Autologous Adipose Cells Therapy - Hair Loss/Baldness, Wrinkle Appearance | Phase 1 / Phase 2 | Recruiting | CERM INC. | 40 | 2025-08-01 | 2025-05-31 |
| Evaluation of the Efficacy of a Cosmetic Light Mask LED Light Treatment, Vibration Only - Fine Lines, Contour | Not applicable | Completed | Therabody, Inc. | 115 | 2025-05-05 | 2025-09-09 |
| Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions RadioFrequency Microneedling Device - Wrinkle, Fine Lines | Not applicable | Unknown | Cynosure, Inc. | 20 | 2023-07-24 | 2024-05-07 |
| A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation Gentle Cleanser, Facial Moisturizer, sunscreen SPF 30 - Fine Lines, Wrinkles | Not applicable | Completed | Revision Skincare | 32 | 2022-01-11 | 2024-10-08 |
| A 12 Week Study to Evaluate the Efficacy of an Eye Cream Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30 - Periorbital Hyperpigmentation, Periorbital Edema | Not applicable | Completed | Revision Skincare | 40 | 2022-01-01 | 2023-11-30 |
| Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device RF Device (Potenza™) - Wrinkles, Fine Lines | Not applicable | Completed | Cynosure, Inc. | 10 | 2021-09-13 | 2023-08-15 |
| A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging Gentle Cleansing Lotion, Revision Skincare - Hyperpigmentation, Photodamaged Skin | Not applicable | Completed | Revision Skincare | 33 | 2021-03-17 | 2022-06-21 |
| A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions KB301, Placebo - Skin Roughness, Wrinkle | Phase 1 | Active not recruiting | Krystal Biotech, Inc. | 85 | 2020-10-07 | 2025-05-13 |
| A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum Anti-aging Serum, Facial Moisturizer, Cleansing Lotion - Fine Lines, Wrinkle | Not applicable | Completed | Revision Skincare | 26 | 2020-09-30 | 2022-03-08 |
| An Open-Label Clinical Study to Evaluate the Efficacy of a Face Cream and Eye Cream Gentle Cleansing Lotion, Revision Skincare, Aveeno Face Milk SPF 40+ - Wrinkle, Photoaging | Not applicable | Completed | Revision Skincare | 45 | 2020-09-11 | 2021-10-06 |
| Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer - Wrinkles, Photoaging | Not applicable | Completed | Revision Skincare | 29 | 2020-08-23 | 2021-10-28 |
| A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines Facial cleanser, Facial moisturizer, Sunscreen - Fine Lines, Wrinkles | Not applicable | Completed | Revision Skincare | 56 | 2019-12-23 | 2020-09-16 |
| Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions Potenza - Wrinkle, Fine Lines | Not applicable | Completed | Cynosure, Inc. | 79 | 2019-09-03 | 2022-06-09 |
Cutis Laxa (4) · Hyperpigmentation (2) · Striae Distensae (2) · Acne Vulgaris (1) · Alopecia (1) · Orbital Cellulitis (1) · Pigmentation Disorders (1)
Skin and Connective Tissue Diseases (8) · Skin Diseases (7) · Connective Tissue Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Skin Diseases, Genetic (4) · Pathological Conditions, Signs and Symptoms (3) · Pigmentation Disorders (2) · Signs and Symptoms (2) · Skin Manifestations (2) · Acneiform Eruptions (1) · Cellulitis (1) · Eye Diseases (1) · Hair Diseases (1) · Hypotrichosis (1)
Sunscreening Agents (3) · 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt (1) · Botulinum Toxins (1) · Botulinum Toxins, Type A (1) · Calcium Carbonate (1) · Starch (1) · Talc (1) · cetyl alcohol, propylene glycol, sodium lauryl sulfate non-lipid cleansing lotion (1)
Revision Skincare (7) · Cynosure, Inc. (3) · NovoBliss Research Pvt Ltd (2) · AB Biotics, SA (1) · CERM INC. (1) · Goldman, Butterwick, Fitzpatrick and Groff (1) · Krystal Biotech, Inc. (1) · Therabody, Inc. (1)
United States (14) · India (1)
Jennifer Civiok (2) · Nayan Patel (2) · Anna Hardy (1) · David McDaniel (1) · Dr. Abdollah M. Malekzadeh, MD, MD (1) · Dr. Arun Kumar, PhD (1) · Emil Tanghetti (1) · Ester Moreno Artero, PhD (1) · Glynis Ablon, MD, FAAD (1) · Robert Weiss (1) · Sean Doherty (1) · Tanja Emmerich, PhD (1)