FGFR2 Gene Translocation: Clinical Trials

4 trials for FGFR2 Gene Translocation, newest first

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2 unknown, 1 completed, 1 terminated. 3 Phase 2, 1 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 23Completed 1, Terminated 1, Unknown 1
Phase 11Completed 1

Follow FGFR2 Gene Translocation: new trials by email Literature Review of FGFR2 Gene Translocation trials Research Report on FGFR2 Gene Translocation

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements
Pemigatinib - Intrahepatic Cholangiocarcinoma, FGFR2 Gene Mutation
Phase 2TerminatedInstitut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest22022-11-112025-04-13
Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)
Data collection and quality of life questionnaire - Cancer, Cancer Metastatic
UnknownCentre Leon Berard5002021-06-222021-08-02
REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors
RLY-4008 - FGFR2 Amplification, FGFR2 Gene Mutation
Phase 1 / Phase 2CompletedElevar Therapeutics4902020-09-022026-02-27
Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations
Pemigatinib, Quality-of-Life Assessment - FGFR1 Gene Amplification, FGFR1 Gene Mutation
Phase 2UnknownAcademic and Community Cancer Research United142020-08-312024-02-21

Narrower conditions

Cholangiocarcinoma (2)  ·  Colorectal Neoplasms (1)  ·  Neoplasm Metastasis (1)  ·  Neoplasms (1)

Broader conditions

Neoplasms (3)  ·  Adenocarcinoma (2)  ·  Carcinoma (2)  ·  Neoplasms by Histologic Type (2)  ·  Neoplasms, Glandular and Epithelial (2)  ·  Colonic Diseases (1)  ·  Digestive System Diseases (1)  ·  Digestive System Neoplasms (1)  ·  Gastrointestinal Diseases (1)  ·  Gastrointestinal Neoplasms (1)  ·  Intestinal Diseases (1)  ·  Intestinal Neoplasms (1)  ·  Neoplasms by Site (1)  ·  Neoplastic Processes (1)  ·  Pathologic Processes (1)

Interventions

pemigatinib (2)  ·  Data Collection (1)

Sponsors

Academic and Community Cancer Research United (1)  ·  Centre Leon Berard (1)  ·  Elevar Therapeutics (1)  ·  Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest (1)

Countries

Germany (3)  ·  France (2)  ·  Italy (2)  ·  Netherlands (2)  ·  Spain (2)  ·  United Kingdom (2)  ·  United States (2)  ·  Australia (1)  ·  Austria (1)  ·  Czechia (1)  ·  Denmark (1)  ·  Hong Kong (1)  ·  Poland (1)  ·  Singapore (1)  ·  Slovenia (1)

Top investigators

Kristen K Ciombor (1)  ·  Salah-Eddin Al-Batran, Prof. Dr. (1)  ·  Thorsten Goetze, Prof. Dr. (1)

Results publications

PMID 40515475, PMID 41571046

NIH funding

P30CA015083 (1)