1 completed, 1 terminated, 1 unknown. 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Completed 1, Terminated 1, Unknown 1 |
Follow Eye Disorders Congenital: new trials by email Literature Review of Eye Disorders Congenital trials Research Report on Eye Disorders Congenital
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single Ascending Dose Study in Participants With LCA10 EDIT-101 - Leber Congenital Amaurosis 10, Inherited Retinal Dystrophies | Phase 1 / Phase 2 | Unknown | Editas Medicine, Inc. | 34 | 2019-09-26 | 2022-12-05 |
| Extension Study to Study PQ-110-001 (NCT03140969) QR-110 - Leber Congenital Amaurosis 10, Blindness | Phase 1 / Phase 2 | Terminated | Laboratoires Thea | 9 | 2019-05-13 | 2024-10-15 |
| Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene QR-421a, Sham-procedure (dose cohort 1&2 only) - Retinitis Pigmentosa, Usher Syndrome Type 2 | Phase 1 / Phase 2 | Completed | ProQR Therapeutics | 20 | 2019-03-06 | 2022-04-20 |
Eye Abnormalities (3) · Eye Diseases, Hereditary (3) · Retinal Diseases (3) · Vision Disorders (3) · Eye Diseases (2) · Leber Congenital Amaurosis (2) · Leber Congenital Amaurosis 10 (2) · Meckel Syndrome, Type 4 (2) · Blindness (1) · Congenital Abnormalities (1) · Genetic Diseases, Inborn (1) · Neurologic Manifestations (1) · Optic Atrophy, Hereditary, Leber (1) · Retinal Degeneration (1) · Retinitis Pigmentosa (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Nervous System Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Congenital Abnormalities (2) · Genetic Diseases, Inborn (2) · Neurologic Manifestations (2) · Sensation Disorders (2) · Abnormalities, Multiple (1) · Blindness (1) · Cranial Nerve Diseases (1) · Deaf-Blind Disorders (1) · Deafness (1) · Ear Diseases (1) · Eye Diseases (1)
Editas Medicine, Inc. (1) · Laboratoires Thea (1) · ProQR Therapeutics (1)
United States (3) · Belgium (1) · Canada (1) · France (1)
PMID 31215818, PMID 33497524, PMID 34629400, PMID 37418643, PMID 38709228
2018 (2)