7 completed, 2 active not recruiting, 2 unknown. 3 Not applicable, 3 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Extramedullary Plasmacytoma: new trials by email Literature Review of Extramedullary Plasmacytoma trials Research Report on Extramedullary Plasmacytoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease Daratumumab, Bortezomib, Cyclophosphamide - Multiple Myeloma, Extramedullary Plasmacytoma | Phase 2 | Active not recruiting | Stichting European Myeloma Network | 41 | 2019-10-31 | 2026-04-20 |
| a Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients Allogeneic Hematopoietic Stem Cell Transplantation, Autologous Hematopoietic Stem Cell Transplantation x 1 or x 2, Melphalan Given IV - Multiple Myeloma, Plasma Cell Leukemia | Not applicable | Unknown | Institute of Hematology & Blood Diseases Hospital, China | 50 | 2018-01-05 | 2019-07-05 |
| CDD Plus Bortezomib or CDDin Relapsed or Refractory Multiple Myeloma With Extramedullary Plasmacytoma CDD, CDD Plus Bortezomib - Extramedullary Plasmacytoma | Phase 3 | Unknown | Beijing Chao Yang Hospital | 100 | 2014-12-01 | 2015-01-13 |
| Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma dexamethasone, cisplatin, doxorubicin - Extramedullary Plasmacytoma, Isolated Plasmacytoma of Bone | Phase 2 | Completed | Margarida Magalhaes-Silverman | 41 | 2013-04-04 | 2022-05-11 |
| Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant tetanus-CMV fusion peptide vaccine, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 | Completed | City of Hope Medical Center | 36 | 2012-10-29 | 2024-04-02 |
| Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant infection prophylaxis and management, laboratory biomarker analysis, flow cytometry - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Active not recruiting | City of Hope Medical Center | 153 | 2011-01-11 | 2026-10-22 | |
| Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer massage therapy, questionnaire administration, quality-of-life assessment - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Wake Forest University Health Sciences | 80 | 2010-04-01 | 2018-07-02 |
| Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy sunitinib malate, pharmacological study, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 1 | Completed | National Cancer Institute (NCI) | 42 | 2009-08-01 | 2014-03-17 |
| Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer beclomethasone dipropionate, placebo, tacrolimus - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 140 | 2007-04-01 | 2021-02-03 |
| Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction imatinib mesylate, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Phase 1 | Completed | National Cancer Institute (NCI) | 60 | 2001-08-01 | 2013-02-07 |
| Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Fred Hutchinson Cancer Center | 5 | 1999-11-01 | 2017-05-24 |
Multiple Myeloma (10) · Burkitt Lymphoma (7) · Leukemia, Lymphocytic, Chronic, B-Cell (7) · Leukemia, Myeloid, Accelerated Phase (7) · Leukemia, Myeloid, Chronic-Phase (7) · Leukemia, Myelomonocytic, Chronic (7) · Lymphoma, Large B-Cell, Diffuse (7) · Lymphoma, T-Cell, Cutaneous (7) · Mycosis Fungoides (7) · Pdgfra-Associated Chronic Eosinophilic Leukemia (7) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (7) · Primary Myelofibrosis (7) · Sezary Syndrome (7) · Thrombocythemia, Essential (7) · Hodgkin Disease (6)
Blood Protein Disorders (10) · Cardiovascular Diseases (10) · Hematologic Diseases (10) · Hemic and Lymphatic Diseases (10) · Hemorrhagic Disorders (10) · Hemostatic Disorders (10) · Immune System Diseases (10) · Immunoproliferative Disorders (10) · Lymphoproliferative Disorders (10) · Neoplasms (10) · Neoplasms by Histologic Type (10) · Paraproteinemias (10) · Vascular Diseases (10) · Neoplasms, Plasma Cell (9) · Blood Coagulation Disorders (7)
Dexamethasone (4) · Bortezomib (3) · Cyclophosphamide (3) · Melphalan (2) · fludarabine phosphate (2) · Antiviral Agents (1) · Beclomethasone (1) · Calcium Dobesilate (1) · Cisplatin (1) · Cyclosporine (1) · Doxorubicin (1) · Drug Therapy (1) · Etoposide (1) · Flow Cytometry (1) · Foscarnet (1)
City of Hope Medical Center (2) · Fred Hutchinson Cancer Center (2) · National Cancer Institute (NCI) (2) · Beijing Chao Yang Hospital (1) · Institute of Hematology & Blood Diseases Hospital, China (1) · Margarida Magalhaes-Silverman (1) · Stichting European Myeloma Network (1) · Wake Forest University Health Sciences (1)
United States (8) · China (2) · Greece (1) · Italy (1) · Turkey (Türkiye) (1)
Ryotaro Nakamura (2) · Ann Woolfrey (1) · Janet Tooze, PhD (1) · John Deeken (1) · Lu G Qiu, Dr. (1) · Margarida Magalhaes-Silverman, MD (1) · Paul Martin (1) · Ramesh Ramanathan (1) · Yuping Zhong, Doctor (1)
PMID 18698002, PMID 22259028, PMID 24474568, PMID 26853648, PMID 30562587
2019 (1), P01CA018029 (1), P30CA015704 (1), P30CA086862 (1), U01CA062487 (1), U01CA062491 (1), U01CA062502 (1), U01CA062505 (1), U01CA099168 (1), U01CA121947 (1)