6 completed, 3 recruiting, 2 terminated, 1 suspended. 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 1 | Completed 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Exostoses, Multiple Hereditary: new trials by email Literature Review of Exostoses, Multiple Hereditary trials Research Report on Exostoses, Multiple Hereditary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Survey on Multiple Osteochondromas and Enchondromatoses During the Transition From Paediatric Care to Adult Care Multiple Osteochondroma, Enchondromatosis | Completed | Istituto Ortopedico Rizzoli | 91 | 2025-11-24 | 2026-09-24 | |
| Descriptive Analysis of Surgeries in Patients With Multiple Osteochondromas Surgery for osteochondromas - Multiple Osteochondroma | Recruiting | Istituto Ortopedico Rizzoli | 300 | 2025-10-23 | 2026-05-15 | |
| Functional and Morphological Characterization of Multiple Osteochondromas Disorder Hereditary Multiple Osteochondromas | Recruiting | Istituto Ortopedico Rizzoli | 60 | 2025-05-21 | 2026-03-24 | |
| Ready to Sail: Evaluating Sailing's Feasibility as Ergotherapy 5-day sailing activity - Multiple Osteochondroma, Ollier Disease | Not applicable | Completed | Istituto Ortopedico Rizzoli | 8 | 2024-05-16 | 2025-03-21 |
| Resilience and Coping in a Rare Skeletal Disease Population to Face Coronavirus (COVID-19) Outbreak Distress: a Longitudinal Study Multiple Osteochondroma, Osteogenesis Imperfecta | Completed | Istituto Ortopedico Rizzoli | 15 | 2021-05-12 | 2023-03-01 | |
| An Efficacy and Safety Study of Palovarotene for the Treatment of MO Palovarotene 2.5 mg, Palovarotene 5.0 mg, Placebo - Exostoses, Multiple Hereditary | Phase 2 | Terminated | Clementia Pharmaceuticals Inc. | 193 | 2018-03-22 | 2022-08-01 |
| Height, Ulnar Length and Forearm Function in Multiple Hereditary Exostoses blood and buccal swab genetic test, PUL, Range of motion - Exostoses, Multiple Hereditary | Completed | Istituto Ortopedico Rizzoli | 408 | 2018-01-01 | 2023-06-22 | |
| NGS Strategy Effectiveness in Molecular Diagnosis NGS molecular screening - Multiple Osteochondroma, Osteogenesis Imperfecta | Completed | Istituto Ortopedico Rizzoli | 400 | 2014-09-29 | 2018-06-18 | |
| Registry of Multiple Osteochondromas Multiple Osteochondromas | Recruiting | Luca Sangiorgi | 10000 | 2013-06-28 | 2025-11-20 | |
| The Health-Related Quality of Life in Patients With Hereditary Multiple Exostoses Exostoses, Multiple Hereditary | Completed | University of British Columbia | 200 | 2007-05-01 | 2022-05-18 | |
| Gene Mutations and Orthopaedic Symptoms Correlation of Multiple Hereditary Exostoses: Multicentre Project Exostoses, Multiple Hereditary | Suspended | University of British Columbia | 2000 | 2004-06-01 | 2022-05-18 | |
| Establishing the Genetic Profile of Multiple Hereditary Exostoses (HME) in Families of BC Exostoses, Multiple Hereditary | Terminated | University of British Columbia | 2000 | 1998-12-01 | 2011-04-15 |
Enchondromatosis (3) · Osteogenesis Imperfecta (3) · Rare Diseases (2) · COVID-19 (1) · Osteochondroma (1) · Psychological Well-Being (1)
Bone Diseases (12) · Bone Diseases, Developmental (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (12) · Exostoses (12) · Genetic Diseases, Inborn (12) · Hyperostosis (12) · Musculoskeletal Diseases (12) · Neoplasms (12) · Neoplasms by Histologic Type (12) · Neoplasms, Bone Tissue (12) · Neoplasms, Connective Tissue (12) · Neoplasms, Connective and Soft Tissue (12) · Neoplastic Syndromes, Hereditary (12) · Osteochondrodysplasias (12) · Osteochondromatosis (12)
Blood Specimen Collection (1) · Palovarotene (1) · Range of Motion, Articular (1) · Surgical Procedures, Operative (1)
Istituto Ortopedico Rizzoli (7) · University of British Columbia (3) · Clementia Pharmaceuticals Inc. (1) · Luca Sangiorgi (1)
Italy (8) · Canada (4) · Australia (1) · Belgium (1) · France (1) · Japan (1) · Netherlands (1) · Portugal (1) · Spain (1) · Turkey (Türkiye) (1) · United Kingdom (1) · United States (1)
Christine Alvarez, MD (3) · Giovanni Luigi Di Gennaro, MD (1) · Luca Sangiorgi, MD, PhD (1) · Luca Sangiorgi, MD, PhD, MS (1) · Luca Sangiorgi, MD, Phd (1)
PMID 16088908, PMID 22258776, PMID 23401177, PMID 24005199, PMID 41131085, PMID 41188357
2017 (1)