EGFR Exon 20 Mutation: Clinical Trials

2 trials for EGFR Exon 20 Mutation, newest first

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1 active not recruiting, 1 terminated. 2 Phase 1, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 12Active not recruiting 1, Terminated 1
Phase 21Active not recruiting 1

Follow EGFR Exon 20 Mutation: new trials by email Literature Review of EGFR Exon 20 Mutation trials Research Report on EGFR Exon 20 Mutation

Trials (filtered) newest first · largest first

All 2 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
BLU-451, Carboplatin, Pemetrexed - Lung Neoplasm Malignant, Carcinoma, Non-Small-Cell Lung
Phase 1TerminatedBlueprint Medicines Corporation1032022-03-042025-02-10
A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer
CLN-081 - Non Small Cell Lung Cancer, EGFR Exon 20 Mutation
Phase 1 / Phase 2Active not recruitingCullinan Therapeutics Inc.2842019-10-312026-06-17

Narrower conditions

Carcinoma, Non-Small-Cell Lung (2)  ·  Adenocarcinoma (1)  ·  Brain Neoplasms (1)  ·  Bronchial Neoplasms (1)  ·  Carcinoma (1)  ·  Carcinoma, Bronchogenic (1)  ·  Lung Diseases (1)  ·  Lung Neoplasms (1)  ·  Neoplasms (1)  ·  Neoplasms by Histologic Type (1)  ·  Neoplasms by Site (1)  ·  Respiratory Tract Diseases (1)  ·  Respiratory Tract Neoplasms (1)  ·  Thoracic Neoplasms (1)

Broader conditions

Brain Diseases (1)  ·  Bronchial Diseases (1)  ·  Bronchial Neoplasms (1)  ·  Carcinoma, Bronchogenic (1)  ·  Central Nervous System Diseases (1)  ·  Central Nervous System Neoplasms (1)  ·  Lung Diseases (1)  ·  Lung Neoplasms (1)  ·  Neoplasms (1)  ·  Neoplasms by Site (1)  ·  Neoplasms, Glandular and Epithelial (1)  ·  Nervous System Diseases (1)  ·  Nervous System Neoplasms (1)  ·  Respiratory Tract Diseases (1)  ·  Respiratory Tract Neoplasms (1)

Interventions

Carboplatin (1)  ·  Pemetrexed (1)  ·  zipalertinib (1)

Sponsors

Blueprint Medicines Corporation (1)  ·  Cullinan Therapeutics Inc. (1)

Countries

Japan (2)  ·  South Korea (2)  ·  Taiwan (2)  ·  United States (2)  ·  Canada (1)  ·  Hong Kong (1)  ·  Italy (1)  ·  Netherlands (1)  ·  Singapore (1)  ·  Spain (1)

Top investigators

Zosia Piotrowska, MD (1)

Results publications

PMID 33122578, PMID 37384848, PMID 40450572