17 completed, 14 recruiting, 9 not yet recruiting, 7 unknown. 32 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 32 | Completed 15, Recruiting 8, Not yet recruiting 5, Unknown 2, Active not recruiting 1, Enrolling by invitation 1 |
Follow Early Detection of Cancer: new trials by email Literature Review of Early Detection of Cancer trials Research Report on Early Detection of Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Understanding Information Preferences, Risk Perceptions, and Tradeoffs When Making Decisions About Multi-cancer Early Detection Tests Test Performance Information: High Detail, Test Performance Information: Low Detail, Diagnostic Workup Information: High Detail - Early Detection of Cancer | Not applicable | Not yet recruiting | Trustees of Dartmouth College | 3000 | 2027-09-01 | 2026-08-28 |
| Strategies to Decentralize Breast Ultrasound in Rwanda Teleultrasound with Philips Lumify ultrasound probes and Reacts software, Asynchronous virtual feedback - Breast Cancer, Early Detection of Cancer | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 1792 | 2027-01-01 | 2026-06-02 |
| Diagnostic Performance of an AI-Based Multi-Omics Model for Early Lung Cancer Pulmonary Nodules, Early Detection of Cancer | Not yet recruiting | Beijing Chao Yang Hospital | 1050 | 2026-10-21 | 2026-10-20 | |
| Structured Case-Finding for Pancreatic Ductal Adenocarcinoma in Swiss Primary Care: A Feasibility Study Structured case-finding pathway (MRI/MRCP + PancreaSure biomarker assay) - Pancreatic Adenocarcinoma (Ductal Adenocarcinoma), Early Detection of Cancer | Not yet recruiting | Saskia Hendrich | 50 | 2026-10-01 | 2026-07-23 | |
| Breast Ultrasound Screening in Elderly Women: A Multicenter Cluster Randomized Trial Standardized Breast Ultrasound Screening - Breast Neoplasms, Early Detection of Cancer | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 80000 | 2026-09-20 | 2026-09-28 |
| Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) Empower LCS, Call+ Telephone Navigation, Usual Care - Lung Cancer Screening, Lung Neoplasms | Not applicable | Recruiting | University of California, Irvine | 80 | 2026-09-16 | 2026-09-21 |
| Screening Cancer Readiness Through Education and Empowerment for Newcomer Women Screening Cancer Readiness through Education and Empowerment for Newcomer Women, Control group - Cancer Screening, Early Detection of Cancer | Not applicable | Not yet recruiting | Erzincan Binali Yildirim Universitesi | 80 | 2026-08-06 | 2026-08-10 |
| Prospective Sample Collection Study for a Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection - Ovarian Neoplasms, Ovarian Cancer | Not yet recruiting | Tongji Hospital | 1000 | 2026-07-01 | 2026-05-18 | |
| Methylation Profiling in Self-samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers Colli-Pee 20 mL device with UCM, Evalyn Brush - Gynaecological Cancers, Ovarian Cancer | Not applicable | Recruiting | Universiteit Antwerpen | 730 | 2026-06-19 | 2026-10-28 |
| Breast and Cervical Cancer Awareness Training in Visually Impaired Women Cancer Screening Awareness Education for Visually Impaired Women - Persons With Visual Disabilities, Breast Neoplasms | Not applicable | Not yet recruiting | Marmara University | 74 | 2026-06-01 | 2026-04-21 |
| Impact of SMS Messaging on Participation in Colorectal Cancer Screening Text Messaging, Standard invitation and postal reminder letters - Colorectal Neoplasms, Early Detection of Cancer | Not applicable | Recruiting | Corporacion Parc Tauli | 10084 | 2026-05-05 | 2026-06-22 |
| Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore Arm 2: One mailed reminder, Arm 3: Two mailed reminders, Arm 4: Mailed reminder with prescheduled appointment - Mammogram Uptake, Breast Cancer | Not applicable | Enrolling by invitation | National University Hospital, Singapore | 12750 | 2026-03-09 | 2026-06-16 |
| Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up Endometrial Neoplasms, DNA Methylation | Not yet recruiting | Peking Union Medical College Hospital | 3500 | 2026-01-10 | 2025-12-23 | |
| Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome Menstrual cup use - Endometrial Cancer, Lynch Syndrome | Not applicable | Recruiting | Jessica D. St. Laurent, MD | 25 | 2025-11-20 | 2026-06-10 |
| AI-Based Self-Supervised Learning Model Using Non-Contrast Breast MRI for Early Screening and Clinical Utility Evaluation Non-contrast multiparametric breast MRI with AI-based radiomics analysis, Standard radiologist reading of non-contrast multiparametric breast MRI - Breast Cancer Detection, Early Detection of Cancer | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 30000 | 2025-10-01 | 2025-10-03 |
| Exploring the Potential of Artificial Intelligence for Earlier Breast Cancer Detection: A Retrospective Multi-Reader Study Based on AI-Assisted Mammographic Interpretation (EARLIEST-AI) Breast Cancer, AI (Artificial Intelligence) | Active not recruiting | Mammograaf Radioloogiakliinik | 785 | 2025-10-01 | 2026-04-29 | |
| Methylation Profile Test (Methylscape) in Body Fluids for Multi-Cancer Detection and Monitoring in Colombia Methylscape DNA methylation assay - Neoplasms, Solid Tumor | Recruiting | Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo | 3250 | 2025-06-05 | 2026-08-03 | |
| The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI Enhanced Usual Care, Decision Support - Breast Neoplasm Female, Early Detection of Cancer | Not applicable | Recruiting | Georgetown University | 80 | 2025-06-01 | 2025-09-30 |
| Default Option Nudging Intervention to Improve the Adherence Rates of Cancer Screening Default Options - Lung Neoplasms, Stomach Neoplasms | Not applicable | Completed | Harbin Medical University | 1200 | 2025-04-27 | 2026-07-02 |
| A Quasi-Experimental Study to Improve Breast Cancer Awareness Among University Students Breast Cancer Awareness Training - Breast Cancer Awareness, Health Education | Active not recruiting | Mardin Artuklu University | 100 | 2025-04-08 | 2025-08-12 |
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Breast Neoplasms (10) · Lung Neoplasms (8) · Neoplasms (8) · Uterine Cervical Neoplasms (7) · Colorectal Neoplasms (5) · Endometrial Neoplasms (4) · Colonic Neoplasms (3) · Gastrointestinal Neoplasms (3) · Ovarian Neoplasms (3) · Disease (2) · Health Education (2) · Neoplasm, Residual (2) · Patient Compliance (2) · Stomach Neoplasms (2) · Anxiety Disorders (1)
Neoplasms by Site (34) · Neoplasms (32) · Digestive System Diseases (14) · Digestive System Neoplasms (13) · Female Urogenital Diseases (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Genital Diseases (13) · Genital Diseases, Female (13) · Genital Neoplasms, Female (13) · Urogenital Diseases (13) · Urogenital Neoplasms (13) · Gastrointestinal Diseases (12) · Breast Diseases (11) · Skin Diseases (11) · Skin and Connective Tissue Diseases (11)
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GRAIL, Inc. (2) · National Taiwan University Hospital (2) · Abramson Cancer Center at Penn Medicine (1) · Akdeniz University (1) · Andaluz Health Service (1) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Avera McKennan Hospital & University Health Center (1) · Beijing Chao Yang Hospital (1) · Biogipuzkoa Health Research Institute (1) · Brigham and Women's Hospital (1) · Caris Science, Inc. (1) · Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo (1) · City of Hope Medical Center (1) · ClinLogic LLC (1) · Corporacion Parc Tauli (1)
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Aisha Lofters, MD PhD CCFP (1) · Ajay Goel, PhD (1) · Anna Selva Olid, PhD, MPH, MD (1) · Berit Andersen, Prof., MD, Head of Department (1) · Carmen L Lewis, MD, MPH (1) · Celine Marquez, MD (1) · Claire C. Conley, PhD (1) · Daniel S Reuland, MD MPH (1) · David Del Valle, MD (1) · Firmino DB Machado, MD (1) · Gelareh Sadigh (1) · Guangxu Liu (1) · Ilana Graetz, PhD (1)
PMID 18089654, PMID 23623832, PMID 28982833, PMID 29035356, PMID 29325548, PMID 29453190, PMID 29847251, PMID 29894717, PMID 30936001, PMID 32779730, PMID 33211762, PMID 33793424, PMID 34074827, PMID 35606736, PMID 36137619, PMID 36469317, PMID 36907899, PMID 37142092, PMID 37584087, PMID 38572751, PMID 38598511, PMID 38848065, PMID 39137185, PMID 40207404, PMID 42624429, PMID 42773207
P50CA271338 (1), R01CA134722 (1), R01CA255269 (1), R01CA317672 (1)