1 completed, 1 recruiting, 1 unknown, 1 withdrawn. 2 Phase 2, 1 Early Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Recruiting 1, Unknown 1 |
| Early Phase 1 | 1 | Withdrawn 1 |
| Phase 4 | 1 | Completed 1 |
Follow DNA Damage Repair Deficiency: new trials by email Literature Review of DNA Damage Repair Deficiency trials Research Report on DNA Damage Repair Deficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer) Cyclosporin A - Triple Negative Breast Cancer, DNA Damage Repair Deficiency | Early Phase 1 | Withdrawn | Virginia G. Kaklamani | 2024-07-01 | 2025-07-16 | |
| The Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate Cancer Docetaxel, Prednisolone Acetate, Platinum-based drugs - Hormone Sensitive Metastatic Prostate Cancer, DNA Damage Repair Deficiency | Phase 2 | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 50 | 2022-07-01 | 2022-10-24 |
| Melatonin and DNA Damage Study Melatonin, Placebo - Sleep Quality, DNA Damage Repair Deficiency | Phase 4 | Completed | University of British Columbia | 40 | 2022-06-01 | 2024-08-28 |
| Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based Chemotherapy Durvalumab, Olaparib - Biliary Tract Cancer, DNA Damage Repair Deficiency | Phase 2 | Recruiting | Asan Medical Center | 62 | 2022-04-01 | 2025-01-28 |
Biliary Tract Neoplasms (1) · Sleep Initiation and Maintenance Disorders (1) · Triple Negative Breast Neoplasms (1)
Neoplasms (2) · Neoplasms by Site (2) · Biliary Tract Diseases (1) · Breast Diseases (1) · Breast Neoplasms (1) · Digestive System Diseases (1) · Digestive System Neoplasms (1) · Dyssomnias (1) · Mental Disorders (1) · Nervous System Diseases (1) · Skin Diseases (1) · Skin and Connective Tissue Diseases (1) · Sleep Disorders, Intrinsic (1) · Sleep Wake Disorders (1)
Cyclosporine (1) · Docetaxel (1) · Melatonin (1) · durvalumab (1) · olaparib (1) · prednisolone acetate (1)
Asan Medical Center (1) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (1) · University of British Columbia (1) · Virginia G. Kaklamani (1)
Canada (1) · China (1) · South Korea (1) · United States (1)
Changhoon Yoo (1) · Hongqian Guo (1) · Virginia Kaklamani, MD, DSc (1)