65 completed, 35 unknown, 5 active not recruiting, 4 not yet recruiting. 77 Not applicable, 12 Phase 4, 5 Phase 3, 4 Phase 2, 1 Early Phase 1.
Follow Dental Caries in Children: new trials by email Literature Review of Dental Caries in Children trials Research Report on Dental Caries in Children
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries 5% Sodium Fluoride Varnish, 2% Chlorhexidine Pre-Treatment + 5% NaF Varnish, Standard Oral Hygiene Education - Dental Caries, Dental Caries in Children | Not applicable | Recruiting | Gül Keskin | 80 | 2026-05-15 | 2026-06-02 |
| Clinical and Radiographic Evaluation of Injectable Composite Versus Packable Composite in Restoring of Primary Molars packable composite, injectable composite - Dental Caries in Children | Not applicable | Not yet recruiting | Eslam samy abdel monaem kalboush | 32 | 2026-05-01 | 2026-04-15 |
| 3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children indirect- 3D digital scanning - Dental Caries in Children, Tooth Erosion | Not applicable | Completed | Indiana University | 36 | 2025-11-04 | 2026-05-06 |
| Different Luting Cements for Pediatric Zirconia Crowns Zirconia crown cemented with Predicta® Bioactive Cement, Zirconia crown cemented with resin-cement - Dental Caries in Children | Not applicable | Not yet recruiting | Cairo University | 60 | 2025-08-28 | 2025-09-03 |
| 3D-printed Ceromer Crowns Versus Stainless Steel in Posterior Primary Molars Personalized 3D-printed pediatric ceromer crown, Prefabricated stainless steel crown group - Caries, Dental, Caries; Dentin | Not applicable | Not yet recruiting | Universidad Autonoma de Baja California | 40 | 2025-07-30 | 2025-07-29 |
| Clinical and Radiographic Evaluation of Zirconomer Restorative zirconia reinforced glass ionomer, Glass ionomer cement - Dental Caries in Children, Dental Materials | Not applicable | Completed | Cairo University | 30 | 2025-04-01 | 2026-08-12 |
| Aesthetic Restorations in Deciduous Anterior Teeth Restoration with resin composite and polyvinyl crown, Restoration with conventional resin composite - Dental Caries in Children | Phase 3 | Not yet recruiting | University of Nove de Julho | 194 | 2025-01-26 | 2024-11-22 |
| Maternal Control of the Child's Feeding, Child's Eating Behavior and Early Childhood Caries in Preschoolers Dental Caries in Children, Diet Habit | Enrolling by invitation | Ain Shams University | 208 | 2025-01-01 | 2025-03-27 | |
| Two Different Minimal Invasive Techniques in Caries Removal of Primary Teeth ART, Brix 3000, Carie Move - Dental Caries in Children | Not applicable | Active not recruiting | Hams Hamed Abdelrahman | 88 | 2024-10-01 | 2025-01-06 |
| Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Caries Technology-enabled anticipatory guidance and peer support, Conventional health education - Dental Caries, Dental Caries in Children | Not applicable | Recruiting | National University of Singapore | 600 | 2024-06-15 | 2024-08-19 |
| Gurney Journey: Virtual Reality Distraction Standard Child Life Preparation and Support + Meta Quest 2 VR headset with Gurney Journey (a mixed reality experience), Standard Child Life Preparation and Support - Dental Caries in Children, Dental Diseases | Not applicable | Completed | Children's Hospital Colorado | 58 | 2024-04-19 | 2025-06-26 |
| Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases Lumoral Treatment, Standard, personalized oral health care - Dental Caries in Children, Dental Plaque | Not applicable | Completed | Wellbeing Services County of Pirkanmaa | 97 | 2024-04-18 | 2026-10-19 |
| Dietary Impacts on Oral Health in Autistic Children: A Cross-Sectional Analysis dietary preferences and their implications for oral health in children with Autism Spectrum Disorder - Dental Caries in Children, Autistic Disorder | Unknown | King Khalid University | 50 | 2024-03-25 | 2024-03-15 | |
| Impact of Oral Health Program on Al-Lith Children's KAP The oral health education intervention program - Dental Caries in Children | Not applicable | Recruiting | Universiti Putra Malaysia | 430 | 2024-03-01 | 2025-07-15 |
| Comparison of Cariostatic Effect of Nano-Silver Fluoride Versus Silver Diamine Fluoride Nano-Silver Fluoride, Silver diamine fluoride - Dental Caries in Children | Phase 1 | Active not recruiting | Cairo University | 78 | 2024-02-07 | 2024-10-16 |
| Comparing the Effectiveness of Papain Based Chemico-mechanical Caries Removal Gel and 38% Silver Diamine Fluoride for Treating Active Caries Lesion of Primary Molars Cera-bur, Brix3000, E-SDF - Dental Caries in Children | Not applicable | Completed | Al-Mustansiriyah University | 45 | 2024-01-02 | 2025-05-08 |
| RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda Use of toothbrush/toothpaste/fluoride varnish, Education on nutrition/oral hygiene - Dental Caries, Dental Plaque | Not applicable | Suspended | University of Bern | 610 | 2023-09-01 | 2025-09-24 |
| Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel. Ethyl Chloride spray (group A), Benzocaine gel 20% (group B) - Dental Caries in Children, Anesthesia, Local | Not applicable | Unknown | Mohammed Bin Rashid University of Medicine and Health Sciences | 42 | 2023-09-01 | 2023-08-25 |
| The Success Rate and Acceptability of Conventional and Modified Hall Crowns Among Children and Parents Hall Crown Technique, Modified Hall Technique - Paediatric Dentistry, Dental Caries in Children | Not applicable | Active not recruiting | King Abdullah University Hospital | 121 | 2023-08-04 | 2025-05-11 |
| The Effect of Oral Health Education on Knowledge, Attitude, Practice and Dental Caries Among Egyptian School Children Oral health education - Dental Caries in Children, Knowledge, Attitudes, Practice | Completed | Cairo University | 115 | 2023-07-30 | 2025-01-24 |
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Dental Caries (35) · Stomatognathic Diseases (5) · Dental Plaque (4) · Child Behavior (3) · Feeding Behavior (3) · Behavior (2) · COVID-19 (2) · Pain (2) · Tooth Erosion (2) · Autistic Disorder (1) · Bites and Stings (1) · Body Weight (1) · Bottle Feeding (1) · Communicable Diseases (1) · Dental Enamel Hypomineralization (1)
Tooth Diseases (40) · Stomatognathic Diseases (38) · Tooth Demineralization (36) · Behavior (10) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (5) · Dental Deposits (4) · Behavior, Animal (3) · Infections (3) · Neurologic Manifestations (3) · Tooth Abnormalities (3) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Coronaviridae Infections (2) · Coronavirus Infections (2)
silver diamine fluoride (14) · Bifluorid 12 (5) · Sodium Fluoride (3) · Composite Resins (2) · Dental Atraumatic Restorative Treatment (2) · Glass Ionomer Cements (2) · Health Education, Dental (2) · Midazolam (2) · Pemetrexed (2) · Amyloid (1) · Anesthesia, Local (1) · CMW cement (1) · Carticaine (1) · Cementation (1) · Clinpro Sealant (1)
Cairo University (15) · University of Sao Paulo (4) · Advantage Silver Dental Arrest, LLC (3) · Ain Shams University (3) · Faculty Sao Leopoldo Mandic Campinas (3) · Suez Canal University (3) · University of Malaya (3) · Mats Bågesund (2) · Recep Tayyip Erdogan University Training and Research Hospital (2) · TC Erciyes University (2) · Ahram Canadian University (1) · Akdeniz University (1) · Al-Azhar University (1) · Al-Mustansiriyah University (1) · Ankara Yildirim Beyazıt University (1)
Egypt (26) · United States (13) · Turkey (Türkiye) (12) · Brazil (10) · Saudi Arabia (5) · Malaysia (4) · Sweden (4) · Dominican Republic (2) · Germany (2) · Iraq (2) · Mexico (2) · Peru (2) · United Kingdom (2) · Argentina (1) · Belgium (1)
Daniela P Raggio, PhD (2) · Eman S Elmasry, Professor (2) · Fatma KI Abdelgawad, Lecturer (2) · Nevine G Waly, Professor (2) · Abla Arafa (1) · Ahmed Akram Elawady (1) · Alan Velazquez, DDS, MPH (1) · Alexander Alcaraz, DDS (1) · Aline Castilho, DDS (1) · Amira Badran, PhD (1) · Amr Ezzat, Professor (1) · Ana Lucia Vollu, MSD Student (1) · Anas Imran Arshad, MSc., BDS (1)
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U54DE019275 (1), UG3DE029169 (1), UH3DE025483 (1)