8 completed, 3 terminated, 1 recruiting, 1 unknown. 2 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Cutaneous Leishmaniases: new trials by email Literature Review of Cutaneous Leishmaniases trials Research Report on Cutaneous Leishmaniases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OPTImizing MIltefosine Treatment for Cutaneous LEISHmaniasis Patients Miltefosine - Cutaneous Leishmaniases | Recruiting | Institute of Tropical Medicine, Belgium | 80 | 2024-06-18 | 2024-07-23 | |
| Study of Cases of Cutaneous Leishmaniasis Treated With Miltefosine in French Guiana, Retrospective Study Data collection, Questionnaires - Cutaneous Leishmaniases, Treatment Adherence | Unknown | Centre Hospitalier de Cayenne | 20 | 2022-08-08 | 2022-08-09 | |
| Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in Ethiopia skin biopsy, venous blood sample (plasma, PBMC, WB), venous blood sample (HLA) - Cutaneous Leishmaniases | Completed | Institute of Tropical Medicine, Belgium | 92 | 2022-03-21 | 2025-01-09 | |
| A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand Flies biting by Phlebotomus duboscqi infected with Leishmania major - Leishmaniasis, Cutaneous Leishmaniases | Not applicable | Completed | University of York | 12 | 2021-10-16 | 2023-11-09 |
| Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New World Meglumine Antimoniate, Miltefosine, Thermotherapy machine - Cutaneous Leishmaniases | Phase 3 | Completed | Drugs for Neglected Diseases | 184 | 2021-01-26 | 2025-05-08 |
| Diagnosis of Cutaneous Leishmaniasis Using the CL-detect Rapid Test in Travelers and Migrants in Belgium Dental Broach - Cutaneous Leishmaniases | Terminated | Institute of Tropical Medicine, Belgium | 6 | 2019-08-12 | 2021-03-04 | |
| Outcomes of Complicated CL in Ethiopia Treated With Miltefosine Miltefosine (administration is not part of study procedures) - Cutaneous Leishmaniases | Completed | Institute of Tropical Medicine, Belgium | 94 | 2019-05-07 | 2020-06-25 | |
| Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects DNDI-0690, Placebo of DNDI-0690 - Visceral Leishmaniasis, Cutaneous Leishmaniases | Phase 1 | Completed | Drugs for Neglected Diseases | 64 | 2019-04-04 | 2022-12-20 |
| Cutaneous Leishmaniasis Diagnostic Study Skin slit, Dental broach, Tape disc - Cutaneous Leishmaniases | Completed | Institute of Tropical Medicine, Belgium | 351 | 2019-02-13 | 2023-03-01 | |
| Complex Cutaneous Leishmaniasis Healing Study in Algeria LeiProtect® - Cutaneous Leishmaniases | Terminated | K. W. Stahl | 20 | 2017-11-01 | 2025-08-03 | |
| Effectiveness, Safety and Feasibility of HECT-CL, in Quetta, Pakistan HECT-CL - Cutaneous Leishmaniases | Phase 3 | Terminated | Medecins Sans Frontieres, Netherlands | 56 | 2017-10-04 | 2019-01-16 |
| Evaluation of Point-of-care Tests for the Diagnosis of Cutaneous Leishmaniasis in Afghanistan LoopampTM Leishmania Detection Kit, CL DetectTM Rapid Test - Cutaneous Leishmaniases | Completed | Foundation for Innovative New Diagnostics, Switzerland | 274 | 2016-04-16 | 2018-02-19 | |
| Efficacy and Safety of Pentamidine (7mg/kg) for Patients With Cutaneous Leishmaniasis Caused by L. Guyanensis Single dose of Pentamidine, Two doses of Pentamidine, Three doses of Pentamidine - Cutaneous Leishmaniases | Phase 2 | Completed | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado | 159 | 2014-01-01 | 2019-02-15 |
Leishmaniasis, Cutaneous (13) · Leishmaniasis (3) · Hyperthermia (1) · Insect Bites and Stings (1) · Leishmaniasis, Visceral (1) · Neglected Diseases (1) · Treatment Adherence and Compliance (1)
Euglenozoa Infections (13) · Infections (13) · Parasitic Diseases (13) · Protozoan Infections (13) · Skin Diseases (13) · Skin Diseases, Infectious (13) · Skin Diseases, Parasitic (13) · Skin and Connective Tissue Diseases (13) · Vector Borne Diseases (13) · Leishmaniasis (10) · Pathological Conditions, Signs and Symptoms (2) · Wounds and Injuries (2) · Behavior (1) · Bites and Stings (1) · Body Temperature Changes (1)
miltefosine (3) · Data Collection (1) · Meglumine Antimoniate (1) · Pentamidine (1) · Surveys and Questionnaires (1)
Institute of Tropical Medicine, Belgium (5) · Drugs for Neglected Diseases (2) · Centre Hospitalier de Cayenne (1) · Foundation for Innovative New Diagnostics, Switzerland (1) · Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (1) · K. W. Stahl (1) · Medecins Sans Frontieres, Netherlands (1) · University of York (1)
Ethiopia (4) · United Kingdom (2) · Belgium (1) · Bolivia (1) · Brazil (1) · Germany (1) · Pakistan (1) · Panama (1) · Peru (1)
Johan van Griensven, MD,PhD (2) · Anette Talhari, Doctor (1) · Charles Lacey, BMBS, MD (1) · Fiorela Yuly Alvarez Romero (1) · Glaucia Cota (1) · Israel Cruz, PhD (1) · Jaime Soto (1) · Johan van Griensven, MD, PhD (1) · Juan Miguel Pascale (1) · Koert Ritmeijer, PhD (1) · Marcia Hueb (1) · Martijn Vink, MD, MPH (1) · Mikias Woldetensay, MD (1) · Paulo Machado (1) · Rezika Mohammed, MD (1)
PMID 30379814, PMID 34048461, PMID 34053461, PMID 35041672, PMID 39095597
2018 (1)