9 terminated. 9 Phase 1, 1 Phase 2.
By phase and status
Follow Chronic Hepatitis B: new trials by email Literature Review of Chronic Hepatitis B trials Research Report on Chronic Hepatitis B
Trials (filtered) newest first · largest first
All 9 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix .
Trial Phase Status Sponsor Enrollment Start Updated
A Phase I, the Study to Evaluate the Safety, Immunogenicity and Efficacy of YS-HBV-002 YS-HBV-002 - Chronic Hepatitis B Phase 1 Terminated 16 2024-07-01 2025-02-24 A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection RO7565020, Placebo, Nucleos(t)ide analogue (NUC) treatment - Chronic Hepatitis B Phase 1 Terminated 60 2023-04-28 2026-01-22 A Study of ALG-125755 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single Doses in Healthy Volunteers, and Single and Multiple Doses in CHB Subjects ALG-125755, Placebo - Chronic Hepatitis B Phase 1 Terminated 57 2022-10-07 2024-03-15 Ethnobridging Study in Healthy Volunteers, Chinese and Japanese Subjects ATI-2173 50 mg - Chronic Hepatitis b Phase 1 Terminated 37 2022-03-29 2022-11-18 A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB Subjects ALG-020572, Placebo - Chronic Hepatitis B Phase 1 Terminated 40 2021-09-25 2023-04-25 A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects ALG-010133, Placebo - Chronic Hepatitis B Phase 1 Terminated 103 2020-08-17 2022-03-15 Study of the Relative Oral Bioavailability of AL-3778 Tablets and Drug Interaction With Entecavir or Tenofovir Disoproxil Fumarate in Healthy Volunteers AL-3778, Entecavir, Tenofovir disoproxil fumarate - Hepatitis B, Chronic Hepatitis B Phase 1 Terminated 54 2017-01-31 2017-10-16 A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection ALN-HBV, Sterile Normal Saline (0.9% NaCl) - Hepatitis B, Chronic Hepatitis B Phase 1 Terminated 24 2016-06-24 2018-09-24 Pharmacokinetic/Pharmacodynamic of Albinterferon Alfa-2b in Chronic Hepatitis B, eAg+, Infection Subjects albinterferon alfa-2b, Pegasys® - Chronic Hepatitis B Phase 1 / Phase 2 Terminated 141 2009-07-01 2011-01-06
Narrower conditions Hepatitis B, Chronic (9) · Hepatitis B (3) · Bronchiolitis Obliterans Syndrome (1)
Broader conditions Blood-Borne Infections (9) · Chronic Disease (9) · Communicable Diseases (9) · DNA Virus Infections (9) · Digestive System Diseases (9) · Disease Attributes (9) · Hepadnaviridae Infections (9) · Hepatitis (9) · Hepatitis, Chronic (9) · Hepatitis, Viral, Human (9) · Infections (9) · Liver Diseases (9) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Virus Diseases (9)
Interventions NVR 3-778 (1) · Nucleobindins (1) · Tenofovir (1) · Therapeutics (1) · albinterferon alfa-2b (1) · entecavir (1) · peginterferon alfa-2a (1)
Sponsors Aligos Therapeutics (3) · Alios Biopharma Inc. (1) · Alnylam Pharmaceuticals (1) · Antios Therapeutics, Inc (1) · Hoffmann-La Roche (1) · Novartis Pharmaceuticals (1) · Yisheng Biopharma (Singapore) Pte. Ltd. (1)
Countries New Zealand (6) · Hong Kong (4) · South Korea (3) · United Kingdom (3) · China (2) · Moldova (2) · Taiwan (2) · Thailand (2) · United States (2) · Australia (1) · Bulgaria (1) · Philippines (1) · Poland (1) · Romania (1) · Singapore (1)
Top investigators Ike Minerva, MD (1) · Stephen Huang, MD (1) · William D Kennedy, MD (1)
Results publications PMID 24995515 , PMID 37290591