41 completed, 1 unknown. 21 Phase 2, 10 Not applicable, 4 Phase 1, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Completed 21 |
| Not applicable | 10 | Completed 10 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 4 | Completed 4 |
Follow Childhood Acute Lymphoblastic Leukemia in Remission: new trials by email Literature Review of Childhood Acute Lymphoblastic Leukemia in Remission trials Research Report on Childhood Acute Lymphoblastic Leukemia in Remission
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Creating a Decision Support System for the Corporate Management of Physical Therapy Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Brain Tumor | Unknown | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 1000 | 2017-11-01 | 2018-07-13 | |
| Culturally Adapted Parenting Intervention for Spanish-Speaking Parents in Improving Outcomes of Younger Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia Survivors at Risk for Late Neurocognitive Effects Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration - Cancer Survivor, Childhood Acute Lymphoblastic Leukemia in Remission | Not applicable | Completed | City of Hope Medical Center | 38 | 2015-10-23 | 2026-10-09 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 84 | 2015-03-23 | 2026-06-01 |
| Let's Play! Healthy Kids After Cancer Phone Coaching Program - Childhood Acute Lymphoblastic Leukemia in Remission, Obesity | Not applicable | Completed | HealthPartners Institute | 42 | 2015-02-01 | 2019-06-10 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children Allogeneic Hematopoietic Stem Cell Transplantation, Fludarabine Phosphate, Laboratory Biomarker Analysis - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 20 | 2014-04-10 | 2024-03-12 |
| ALL-Active: A Family-Based Lifestyle Program for Pediatric Acute Leukemia Patients nutritional intervention, exercise intervention, follow-up care - Childhood Acute Lymphoblastic Leukemia in Remission | Not applicable | Completed | Vanderbilt-Ingram Cancer Center | 33 | 2013-05-01 | 2018-05-08 |
| Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Roswell Park Cancer Institute | 94 | 2012-02-28 | 2019-09-24 |
| Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia laboratory biomarker analysis - B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission | Completed | Children's Oncology Group | 70 | 2012-02-01 | 2016-05-18 | |
| Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies cyclophosphamide, cyclosporine, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 43 | 2011-09-01 | 2017-05-19 |
| A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies Fludarabine, Busulfan, Total Body Irradiation (TBI) - Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 40 | 2011-08-04 | 2026-04-15 |
| Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant supersaturated calcium phosphate rinse, placebo, questionnaire administration - Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 226 | 2011-03-01 | 2019-09-17 |
| Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies umbilical cord blood transplantation, fludarabine phosphate, cyclophosphamide - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission | Phase 2 | Completed | Nohla Therapeutics, Inc. | 15 | 2010-08-01 | 2019-03-05 |
| Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer massage therapy, questionnaire administration, quality-of-life assessment - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Wake Forest University Health Sciences | 80 | 2010-04-01 | 2018-07-02 |
| Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia treosulfan, fludarabine phosphate, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Fred Hutchinson Cancer Center | 96 | 2009-02-01 | 2021-06-22 |
| Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders fludarabine phosphate, melphalan, total-body irradiation - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Not applicable | Completed | Roswell Park Cancer Institute | 62 | 2009-01-14 | 2019-11-13 |
| Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CML nilotinib, imatinib mesylate, pharmacological study - Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 40 | 2008-08-14 | 2017-08-10 |
| Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases allogeneic bone marrow transplantation, laboratory biomarker analysis, filgrastim - Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 27 | 2007-12-31 | 2022-04-28 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer beclomethasone dipropionate, placebo, tacrolimus - Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 140 | 2007-04-01 | 2021-02-03 |
| Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission thiotepa, cyclophosphamide, tacrolimus - B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission | Phase 3 | Completed | Children's Oncology Group | 146 | 2007-03-01 | 2019-08-07 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (35) · Leukemia, Lymphocytic, Chronic, B-Cell (20) · Leukemia, Myeloid, Accelerated Phase (20) · Burkitt Lymphoma (19) · Leukemia, Myeloid, Acute (19) · Lymphoma, Non-Hodgkin (19) · Leukemia, Myeloid, Chronic-Phase (18) · Lymphoma, B-Cell, Marginal Zone (18) · Lymphoma, Follicular (18) · Multiple Myeloma (18) · Congenital Abnormalities (17) · Dendritic Cell Sarcoma, Interdigitating (17) · Hodgkin Disease (17) · Lymphoma, Large B-Cell, Diffuse (17) · Lymphoma, T-Cell, Cutaneous (17)
Hematologic Diseases (37) · Hemic and Lymphatic Diseases (37) · Neoplasms (37) · Neoplasms by Histologic Type (37) · Immune System Diseases (35) · Immunoproliferative Disorders (35) · Leukemia (35) · Leukemia, Lymphoid (35) · Lymphatic Diseases (35) · Lymphoproliferative Disorders (35) · Leukemia, Myeloid (30) · Pathological Conditions, Signs and Symptoms (30) · Bone Marrow Diseases (29) · Chronic Disease (29) · Disease Attributes (29)
Whole-Body Irradiation (21) · fludarabine phosphate (21) · Mycophenolic Acid (18) · Peripheral Blood Stem Cell Transplantation (17) · Cyclosporine (15) · Cyclophosphamide (11) · Tacrolimus (10) · Methotrexate (9) · merphos (9) · Transplantation (8) · Busulfan (6) · Cyclosporins (4) · Melphalan (4) · Thiotepa (4) · Cord Blood Stem Cell Transplantation (3)
Fred Hutchinson Cancer Center (18) · Children's Oncology Group (9) · Roswell Park Cancer Institute (3) · Case Comprehensive Cancer Center (2) · City of Hope Medical Center (1) · Federal Research Institute of Pediatric Hematology, Oncology and Immunology (1) · Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium (1) · HealthPartners Institute (1) · Masonic Cancer Center, University of Minnesota (1) · National Cancer Institute (NCI) (1) · Nohla Therapeutics, Inc. (1) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (1) · Vanderbilt-Ingram Cancer Center (1) · Wake Forest University Health Sciences (1)
United States (41) · Germany (5) · Italy (5) · Australia (3) · Canada (3) · Denmark (1) · Russia (1)
Brenda Sandmaier (5) · Colleen Delaney (2) · David Maloney (2) · George Chen (2) · George Georges (2) · Marie Bleakley (2) · Paul Martin (2) · Adam Esbenshade, MD (1) · Alicia S Kunin-Batson, PhD (1) · Ann Woolfrey (1) · Boglarka Gyurkocza (1) · Brenda Cooper, MD (1) · Christen Ebens, MD (1) · David Gilbert, MD (1) · Gregory Yanik, MD (1)
PMID 32499241, PMID 35007144, PMID 18698002, PMID 21508120, PMID 24497539, PMID 24829202, PMID 25085357, PMID 25624441, PMID 25862561, PMID 26764356, PMID 28817727, PMID 33242441, PMID 35445027, PMID 37070673, PMID 40908865
P30CA015704 (12), P01CA018029 (10), U10CA098543 (6), P01CA078902 (2), R01HL121568 (2), RC2HL101844 (2), U10CA095861 (2), K12CA090625 (1), K23CA154532 (1), P01HL036444 (1), P30CA016056 (1), P30CA068485 (1), R01CA076641 (1), R01CA096670 (1), R21CA182727 (1)