8 unknown, 5 completed, 2 not yet recruiting, 2 recruiting. 10 Not applicable, 2 Phase 1, 1 Early Phase 1, 1 Phase 2, 1 Phase 4.
Follow Childhood Acute Lymphoblastic Leukemia: new trials by email Literature Review of Childhood Acute Lymphoblastic Leukemia trials Research Report on Childhood Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Prolonged Asparaginase Activity Levels After Calaspargase Pegol Administration Non-Interventional Study - Childhood Acute Lymphoblastic Leukemia, Childhood Lymphoblastic Lymphoma | Not yet recruiting | Mayo Clinic | 20 | 2027-02-01 | 2026-04-02 | |
| A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 1 | Withdrawn | Children's Oncology Group | 2026-09-10 | 2026-05-05 | |
| NUDT15/TPMT Multi-gene Guided 6-MP Dosing in Childhood ALL Maintenance Therapy NUDT15/TPMT genotype-guided 6-MP dosing - Childhood Acute Lymphoblastic Leukemia | Not applicable | Not yet recruiting | The Children's Hospital of Zhejiang University School of Medicine | 110 | 2026-02-20 | 2026-03-10 |
| Exploring the Effect of Calaspargase Pegol on the Coagulation System in Pediatric Acute Lymphoblastic Leukemia (ALL) Patients: Pilot Study Non-Interventional Study - Childhood Acute Lymphoblastic Leukemia, Childhood Lymphoblastic Lymphoma | Recruiting | Mayo Clinic | 15 | 2025-07-31 | 2026-02-13 | |
| Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Acute Leukemia, Acute Leukemia of Ambiguous Lineage | Phase 1 | Recruiting | City of Hope Medical Center | 27 | 2024-12-31 | 2026-10-19 |
| A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at Home Biospecimen Collection, Compliance Monitoring, Health Promotion and Education - Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia | Not applicable | Suspended | Children's Oncology Group | 64 | 2024-12-04 | 2026-10-05 |
| Laser Therapy Effect on Oral Mucositis in Childhood Acute Lymphoblastic Leukemia Patients Laser Therapy, Sham procedure - Oral Mucositis, Childhood Acute Lymphoblastic Leukemia | Not applicable | Unknown | Children's Cancer Hospital Egypt 57357 | 51 | 2023-05-16 | 2024-08-21 |
| Goal Management Training for Adult Survivors of Childhood Leukemia and Non-Hodgkins Lymphoma With Neurocognitive Sequelae Goal Management Training (GMT), Brain Health Workshop (BHW) - Childhood Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia | Not applicable | Active not recruiting | Norwegian University of Science and Technology | 60 | 2020-09-04 | 2025-08-19 |
| CAR-T for Children With Relapsed and Refractory Acute Lymphoblastic Leukemia CD19 CAR-T, CD22 CAR-T, CD 19+22 - Childhood Acute Lymphoblastic Leukemia | Early Phase 1 | Unknown | Hebei Senlang Biotechnology Inc., Ltd. | 50 | 2020-04-01 | 2020-11-13 |
| Unravelling the Role of KCTD Protein Family in the Clinical Management of Childhood Acute Lymphoblastic Leukemias observational study - Childhood Acute Lymphoblastic Leukemia | Unknown | IRCCS SYNLAB SDN | 80 | 2020-03-02 | 2024-03-25 | |
| Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2019 Pilot Blinatumomab - Childhood Acute Lymphoblastic Leukemia | Not applicable | Unknown | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 180 | 2020-02-01 | 2021-01-25 |
| Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation 3D-Transit - Constipation, Childhood Acute Lymphoblastic Leukemia | Not applicable | Unknown | University of Aarhus | 80 | 2019-06-13 | 2020-11-25 |
| Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2015 (ALL-MB 2015) Dexamethasone continuous, Dexamethasone intermittent, Dexamethasone - Childhood Acute Lymphoblastic Leukemia | Not applicable | Unknown | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 4000 | 2015-11-01 | 2020-02-05 |
| Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia Idarubicin(IDA) - Childhood Acute Lymphoblastic Leukemia, Philadelphia Chromosome, Ph^1^, Absent | Phase 4 | Unknown | Chinese Academy of Medical Sciences | 20 | 2012-10-01 | 2013-11-21 |
| Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting electroacupuncture therapy, questionnaire administration - Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies | Not applicable | Withdrawn | Stanford University | 2012-05-01 | 2013-06-12 | |
| Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Fludarabine Phosphate - Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 77 | 2010-12-01 | 2019-12-09 |
| Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With Leukemia laboratory biomarker analysis - Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies | Completed | Children's Oncology Group | 18 | 2010-07-01 | 2016-05-18 | |
| Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic Leukemia Asparaginase, Laboratory Biomarker Analysis, Pharmacological Study - Adult Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia | Not applicable | Completed | Children's Oncology Group | 59 | 2008-02-11 | 2019-07-09 |
| Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008 PEG-L-asparaginase ind, PEG-L-asparaginase cons, E.coli L-asparaginase - Childhood Acute Lymphoblastic Leukemia | Not applicable | Unknown | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 3000 | 2008-02-01 | 2020-02-05 |
| Evaluating Dactinomycin and Vincristine in Young Patients With Cancer pharmacological study, laboratory biomarker analysis - Childhood Acute Lymphoblastic Leukemia, Childhood Rhabdomyosarcoma | Completed | Children's Oncology Group | 158 | 2008-02-01 | 2017-05-17 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (21) · Leukemia, Biphenotypic, Acute (3) · Leukemia, Myeloid, Acute (3) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Prolymphocytic (2) · Sarcoma, Ewing (2) · Anemia, Refractory, with Excess of Blasts (1) · Constipation (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1) · Leukemia, Hairy Cell (1) · Leukemia, Large Granular Lymphocytic (1) · Leukemia, Mast-Cell (1) · Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (1) · Leukemia, Myeloid, Chronic-Phase (1)
Hematologic Diseases (21) · Hemic and Lymphatic Diseases (21) · Immune System Diseases (21) · Immunoproliferative Disorders (21) · Leukemia (21) · Leukemia, Lymphoid (21) · Lymphatic Diseases (21) · Lymphoproliferative Disorders (21) · Neoplasms by Histologic Type (21) · Neoplasms (20) · Leukemia, Myeloid (4) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Bone Marrow Diseases (2) · Chronic Disease (2)
Specimen Handling (3) · Asparaginase (2) · Biopsy (2) · Daunorubicin (2) · Idarubicin (2) · Methotrexate (2) · revumenib (2) · Bortezomib (1) · Cholestanetriol 26-Monooxygenase (1) · Cranial Irradiation (1) · Cyclophosphamide (1) · Cyclosporine (1) · Cyclosporins (1) · Cytarabine (1) · Dexamethasone (1)
Children's Oncology Group (6) · Federal Research Institute of Pediatric Hematology, Oncology and Immunology (3) · Mayo Clinic (2) · Children's Cancer Hospital Egypt 57357 (1) · Chinese Academy of Medical Sciences (1) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Center (1) · Hebei Senlang Biotechnology Inc., Ltd. (1) · IRCCS SYNLAB SDN (1) · Norwegian University of Science and Technology (1) · Stanford University (1) · The Children's Hospital of Zhejiang University School of Medicine (1) · University of Aarhus (1)
United States (10) · China (3) · Russia (3) · Australia (2) · Belarus (2) · Canada (2) · Denmark (2) · Uzbekistan (2) · Armenia (1) · Egypt (1) · Italy (1) · Kyrgyzstan (1) · New Zealand (1) · Norway (1) · Puerto Rico (1)
Madeleine B. O'Keefe, MD (2) · Alexander I. Karachunskiy, Professor (1) · Alexander I. Karachunskiy, Professor, MD (1) · Alexander I. Karachunskiy, Professor,MD (1) · Ben K Watkins (1) · Brenda Golianu (1) · Brenda Sandmaier (1) · Brian Ball, MD (1) · Hussein ElNoury, MSc (1) · Jeffrey Skolnik (1) · Jianmin Luo, PhD&MD (1) · Magne Arve Flaten, phd prof (1) · Nilsa Ramirez (1) · Patrick Brown, MD (1) · Paul Georg Skogen (1)
PMID 32603426, PMID 34091540, PMID 38651186, PMID 39552427, PMID 41671463
U10CA098543 (3), P01CA018029 (1), P30CA015704 (1), P30CA033572 (1), UG1CA189955 (1), UG1CA189958 (1), UM1CA228823 (1)