3 completed, 3 unknown, 1 terminated, 1 withdrawn. 4 Not applicable, 2 Phase 1, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 1 | 2 | Unknown 2 |
| Phase 2 | 1 | Withdrawn 1 |
| Phase 3 | 1 | Withdrawn 1 |
| Phase 4 | 1 | Completed 1 |
Follow Cervical Incompetence: new trials by email Literature Review of Cervical Incompetence trials Research Report on Cervical Incompetence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preventing Preterm Birth With a Negative Pressure Cervical Cup: a Feasibility Study Hannah Cervical Cup (2 mm Delta), Hannah Cervical Cup (4 mm Delta), Hannah Cervical Cup (6 mm Delta) - Preterm Birth, Cervical Incompetence | Phase 1 | Unknown | Galena Innovations, LLC | 40 | 2023-04-01 | 2022-08-26 |
| Cervical Occlusion Double-level Stitch Application Double-level cervical cerclage, Single-level cervical cerclage - Cervical Incompetence | Not applicable | Completed | Centre of Postgraduate Medical Education | 81 | 2022-03-11 | 2025-09-30 |
| The FLIP-1 Study: Vaginal Lactobacillus Supplementation in Women at High Risk of Preterm Birth LACTIN-V - Preterm Labor, Preterm Birth | Phase 1 | Unknown | Imperial College London | 60 | 2019-09-16 | 2020-05-28 |
| Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening Cerclage - Preterm Labor, Cervical Incompetence | Not applicable | Unknown | Ain Shams University | 60 | 2019-04-22 | 2019-02-12 |
| Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC) Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML - Cervical Incompetence | Not applicable | Terminated | Hallym University Kangnam Sacred Heart Hospital | 20 | 2018-08-01 | 2020-09-04 |
| Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage Chloroprocaine, Bupivacaine - Cervical Incompetence | Phase 4 | Completed | Tufts Medical Center | 10 | 2017-10-13 | 2020-08-25 |
| Cerclage for Twins With Short Cervix Cervical Cerclage placement, Vaginal Progesterone - Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2 | Phase 2 / Phase 3 | Withdrawn | Pediatrix | 2017-10-01 | 2018-03-21 | |
| Prolene Versus Ethibond for Cervical Cerclage Ethibond Suture, Prolene Suture - Cervical Incompetence | Not applicable | Completed | Rutgers University | 16 | 2017-08-01 | 2020-03-13 |
Uterine Cervical Incompetence (8) · Premature Birth (4) · Obstetric Labor, Premature (2) · Infections (1) · Pregnancy Complications (1) · Preterm Premature Rupture of the Membranes (1)
Abortion, Habitual (8) · Abortion, Spontaneous (8) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Genital Diseases (8) · Genital Diseases, Female (8) · Urogenital Diseases (8) · Uterine Cervical Diseases (8) · Uterine Diseases (8) · Pregnancy Complications (7) · Obstetric Labor Complications (5) · Obstetric Labor, Premature (3)
Bupivacaine (2) · APF protein, Lactobacillus crispatus (1) · Anesthesia, General (1) · Anesthesia, Spinal (1) · Cerclage, Cervical (1) · Progesterone (1) · chloroprocaine (1)
Ain Shams University (1) · Centre of Postgraduate Medical Education (1) · Galena Innovations, LLC (1) · Hallym University Kangnam Sacred Heart Hospital (1) · Imperial College London (1) · Pediatrix (1) · Rutgers University (1) · Tufts Medical Center (1)
United States (3) · Egypt (1) · Poland (1) · South Korea (1) · United Kingdom (1)
Andrew Combs, MD (1) · Anna Kajdy, MD PhD (1) · Ashley C Crafton (1) · Dan Drzymalski, MD (1) · Eunmi Choi, MD.PhD (1) · Katarzyna Kosinska Kaczynska, Prof. (1) · Mariusz Grzesiak, Prof. (1) · Meike Schuster, MD (1) · Phillip Bennett, BSc PhD MD (1) · Yasser Shahawy (1)
PMID 14586323, PMID 16449104, PMID 18177834, PMID 18243484, PMID 22399222, PMID 23201330, PMID 24807330, PMID 26974218, PMID 30928565, PMID 32970845, PMID 36464242, PMID 37286317