12 recruiting, 11 active not recruiting, 11 completed, 7 terminated. 16 Phase 2, 11 Phase 1, 8 Phase 3, 6 Not applicable, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Definitive Radiation Therapy for Inoperable Breast Cancer Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor, Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor and ipsilateral axillary lymph nodes - Breast Cancer, Breast Adenocarcinoma | Not applicable | Recruiting | Alexander Stessin | 30 | 2025-12-08 | 2025-12-17 |
| Effects of Chemotherapy Treatment on Metaboreflex, Mechanoreflex, and Baroreflex Function: PROTECT-08B Study Test of neuromuscular fatigue and associated hemodynamic responses - Breast Adenocarcinoma | Not applicable | Recruiting | Centre Paul Strauss | 24 | 2025-10-02 | 2025-12-31 |
| Personalization of External Beam Radiation Therapy in Localised Tumours prostate patient, breast patients - Breast Adenocarcinoma, Prostate Cancer (Adenocarcinoma) | Recruiting | European Institute of Oncology | 35 | 2025-07-01 | 2025-07-02 | |
| The Application Value of Spectral CT in the Accurate Staging of Breast Cancer To explore the value of spectral CT in the diagnosis and treatment of breast cancer - Breast Adenocarcinoma | Not applicable | Not yet recruiting | Yunnan Cancer Hospital | 150 | 2025-06-01 | 2025-05-18 |
| A Prospective, Multicenter Registry to Observe the Treatment Patterns, Clinical Outcomes, and Decision-Making in Patients With Early Breast Cancer Eligible for EndoPredict® Testing Breast Cancer, Breast Adenocarcinoma | Recruiting | National and Kapodistrian University of Athens | 2000 | 2025-04-01 | 2026-02-05 | |
| Preoperative Radiation Therapy and Immediate Breast Reconstruction Preoperative radiotherapy, Postoperative radiotherapy, Immediate breast reconstruction - Breast Neoplasms, Breast Carcinoma | Not applicable | Recruiting | Cancer Research Antwerp | 180 | 2025-02-20 | 2026-02-04 |
| Neoadjuvant Toripalimab and Radiotherapy Treatment in N+ HR+ Breast Cancer SBRT, Immuno-chemotherapy - Breast Adenocarcinoma | Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 74 | 2024-12-26 | 2025-02-11 |
| Assessing Combined SBRT in Breast Cancer Non-Responders to Neoadjuvant Chemotherapy SBRT, Chemotherapy - Breast Adenocarcinoma | Phase 1 / Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 96 | 2024-12-25 | 2025-12-30 |
| Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas Breast Adenocarcinoma, Luminal B Breast Cancer | Active not recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 80 | 2024-12-01 | 2025-02-03 | |
| High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer Biospecimen Collection, BRC-001, Placebo Administration - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 | Suspended | City of Hope Medical Center | 36 | 2024-08-26 | 2026-07-14 |
| Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy Non-Interventional Study - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Recruiting | Mayo Clinic | 35 | 2024-07-19 | 2026-05-19 | |
| Multi-Institutional Transgender & Gender-Diverse Breast Cancer Study Breast Cancer, Breast Neoplasms | Completed | Medical College of Wisconsin | 125 | 2023-12-08 | 2026-08-27 | |
| Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study Palbociclib, Ribociclib, Abemaciclib - Breast Adenocarcinoma, Breast Cancer Stage IV | Recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 3500 | 2023-05-01 | 2025-02-03 | |
| Explore Association Models Between Environmental Hormones andBreast Cancer Breast Diseases, Breast Adenocarcinoma | Active not recruiting | Pei-Hung Liao | 687 | 2023-03-20 | 2025-01-09 | |
| Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) Rina-S, Carboplatin, Bevacizumab - High Grade Epithelial Ovarian Cancer, High Grade Serous Ovarian Cancer | Phase 1 / Phase 2 | Recruiting | Genmab | 952 | 2022-12-07 | 2026-11-04 |
| Analysis of Letrozole in Patients With Operable Hormone Receptor Positive, HER2 Negative Breast Cancer Biospecimen Collection - Breast Adenocarcinoma, Invasive Breast Carcinoma | Terminated | Mayo Clinic | 21 | 2022-07-21 | 2025-06-15 | |
| Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 138 | 2022-03-31 | 2026-08-20 |
| Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer Biospecimen Collection, Letrozole, Questionnaire Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Phase 4 | Terminated | University of Washington | 62 | 2022-01-23 | 2026-06-04 |
| Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung Cancer Biopsy, Biospecimen Collection, Probiotic - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Early Phase 1 | Completed | Mayo Clinic | 6 | 2021-07-01 | 2023-04-21 |
| Study of the Safety of MRI Scans in People Who Have Breast Tissue Expanders After Mastectomy MRI Studies, Patient Reported Outcomes - Breast Cancer, Breast Neoplasms | Active not recruiting | Memorial Sloan Kettering Cancer Center | 68 | 2021-02-19 | 2026-05-18 |
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Breast Neoplasms (28) · Breast Carcinoma In Situ (7) · Triple Negative Breast Neoplasms (7) · Neoplasm Metastasis (3) · Breast Diseases (2) · Carcinoma, Intraductal, Noninfiltrating (2) · Carcinoma, Non-Small-Cell Lung (2) · Endometrial Neoplasms (2) · Lung Neoplasms (2) · Prostatic Neoplasms (2) · Uterine Cervical Neoplasms (2) · Adenocarcinoma (1) · Adenocarcinoma of Lung (1) · Breast Neoplasms, Male (1) · Carcinoma, Ductal (1)
Neoplasms (38) · Neoplasms by Site (38) · Skin Diseases (36) · Skin and Connective Tissue Diseases (36) · Breast Diseases (33) · Neoplasms by Histologic Type (14) · Neoplasms, Glandular and Epithelial (12) · Carcinoma (11) · Breast Neoplasms (7) · Carcinoma in Situ (7) · Adenocarcinoma (5) · Genital Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Urogenital Diseases (5) · Male Urogenital Diseases (4)
Paclitaxel (7) · Taxes (7) · Cyclophosphamide (6) · Specimen Handling (6) · Doxorubicin (5) · Trastuzumab (5) · pembrolizumab (5) · Magnetic Resonance Spectroscopy (4) · Albumin-Bound Paclitaxel (3) · Biopsy (3) · Carboplatin (3) · Ogivri (3) · Ontruzant (3) · PF-05280014 (3) · trastuzumab biosimilar HLX02 (3)
Mayo Clinic (10) · National Cancer Institute (NCI) (5) · M.D. Anderson Cancer Center (3) · Academic and Community Cancer Research United (2) · City of Hope Medical Center (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Virginia Commonwealth University (2) · Alexander Stessin (1) · Alliance for Clinical Trials in Oncology (1) · Cancer Research Antwerp (1) · Centre Leon Berard (1) · Centre Paul Strauss (1) · Eisai Inc. (1) · European Institute of Oncology (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1)
United States (35) · Canada (3) · China (3) · France (3) · Italy (3) · Peru (3) · South Africa (3) · Puerto Rico (2) · United Kingdom (2) · Australia (1) · Belgium (1) · Greece (1) · Ireland (1) · Japan (1) · New Zealand (1)
Saranya Chumsri (3) · Roisin M Connolly (2) · Saranya Chumsri, M.D. (2) · Alexander Stessin, MD PhD (1) · Alicia Meng, MD (1) · Andrew L. Himelstein, MD (1) · Anita H. Chen, M.D. (1) · Chandler S Cortina (1) · Clinton Yam (1) · Douglas W Arthur, M.D. (1) · Edith A Perez (1) · Giulia Marvaso (1) · Grzegorz S. Nowakowski, M.D. (1) · Harry D. Bear, M.D., Ph.D. (1) · Jennifer K Litton (1)
PMID 16236738, PMID 22042958, PMID 25332249, PMID 25605861, PMID 26101239, PMID 26412349, PMID 26429296, PMID 26469139, PMID 28030702, PMID 28646344, PMID 29860917, PMID 29898752, PMID 30040523, PMID 30054636, PMID 30808774, PMID 31157962, PMID 31409130, PMID 31461380, PMID 31566680, PMID 31622131, PMID 32271671, PMID 33626896, PMID 34090143, PMID 34137783, PMID 34357781, PMID 34384695, PMID 34726788, PMID 34980541, PMID 35175284, PMID 35226083, PMID 35610260, PMID 35642432, PMID 35736816, PMID 36796498, PMID 37043210, PMID 37061619, PMID 37441546, PMID 39191270, PMID 40446745, PMID 40830892, PMID 40966714, PMID 41103105, PMID 42046025
U10CA021115 (3), U10CA180820 (3), P30CA015083 (2), 2018 (1), P30CA013330 (1), P30CA015704 (1), P30CA016059 (1), P30CA033572 (1), R01CA098473 (1), R01CA166020 (1), U10CA025224 (1), U10CA037447 (1), U10CA180821 (1), U10CA180868 (1), U24CA196172 (1)