4 completed, 2 recruiting, 1 unknown. 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 1 | Recruiting 1 |
Follow Beta Lactam Adverse Reaction: new trials by email Literature Review of Beta Lactam Adverse Reaction trials Research Report on Beta Lactam Adverse Reaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimization of Perioperative Antibiotic Prophylaxis in Patients Allergic to Beta-lactams in the Orthopedic Surgery and Trauma Departments Beta Lactam Adverse Reaction | Recruiting | University Hospital, Strasbourg, France | 50 | 2025-07-11 | 2026-01-15 | |
| Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing, Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge, Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge - Drug Allergy, Cephalosporin Allergy | Phase 2 | Recruiting | Massachusetts General Hospital | 300 | 2025-05-05 | 2026-09-04 |
| B-lactam Databank Algorithm Beta Lactam Adverse Reaction | Completed | University Hospital, Antwerp | 921 | 2023-12-11 | 2024-08-19 | |
| Investigation of Cross-allergies Between Cefazolin and Amoxicillin With Skin Tests and Provocation Test Allergic Reaction, Beta Lactam Adverse Reaction | Unknown | Fondation Hôpital Saint-Joseph | 84 | 2022-10-28 | 2023-03-07 | |
| Protocol of Reintroduction of Beta-lactams in Children at Low Risk of Anaphylaxis. Hypersensitivity, Beta Lactam Adverse Reaction | Completed | Nantes University Hospital | 195 | 2018-09-07 | 2026-06-24 | |
| Beta-lactam Pharmacokinetics in Secondary Care Beta-lactam antibiotic - Pharmacokinetics, Beta Lactam Adverse Reaction | Completed | Imperial College London | 65 | 2017-07-12 | 2021-08-30 | |
| The Diagnosis of Beta-lactam Hypersensitivity in Thailand Penicillin Allergy, Aminopenicillin Allergy | Completed | Chulalongkorn University | 500 | 2012-06-01 | 2019-10-29 |
Hypersensitivity (3) · Drug Hypersensitivity (2) · Anaphylaxis (1) · Drug-Related Side Effects and Adverse Reactions (1)
Immune System Diseases (3) · Chemically-Induced Disorders (2) · Drug-Related Side Effects and Adverse Reactions (1) · Hypersensitivity, Immediate (1)
Monobactams (2) · Ampicillin (1) · Cefaclor (1) · Cefadroxil (1) · Cefazolin (1) · Cefdinir (1) · Cefepime (1) · Cefixime (1) · Cefotaxime (1) · Cefpodoxime (1) · Ceftazidime (1) · Ceftriaxone (1) · Cefuroxime (1) · Cephalexin (1) · Histamine (1)
Chulalongkorn University (1) · Fondation Hôpital Saint-Joseph (1) · Imperial College London (1) · Massachusetts General Hospital (1) · Nantes University Hospital (1) · University Hospital, Antwerp (1) · University Hospital, Strasbourg, France (1)
France (3) · Belgium (1) · Thailand (1) · United Kingdom (1) · United States (1)
Alison H Holmes, MD MPH MBBS (1) · David A Khan, MD (1) · Jettanong Klaewsongkram, MD (1) · Kimberly G Blumenthal, MD, MSc (1)
U01AI184071 (1)