5 completed, 1 recruiting, 1 terminated. 7 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 7 | Completed 5, Recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
Follow B-cell Childhood Acute Lymphoblastic Leukemia: new trials by email Literature Review of B-cell Childhood Acute Lymphoblastic Leukemia trials Research Report on B-cell Childhood Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Blinatumomab After TCR Alpha Beta/CD19 Depleted HCT Alpha/Beta T-cell and B-cell depleted HCT, Blinatumomab - B-cell Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Medical College of Wisconsin | 25 | 2021-02-01 | 2021-09-17 |
| Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma L-asparaginase, doxorubicin hydrochloride, therapeutic hydrocortisone - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | National Cancer Institute (NCI) | 148 | 2009-03-01 | 2017-01-27 |
| Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma rituximab, peripheral blood stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation - B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia | Phase 2 | Completed | Fred Hutchinson Cancer Center | 63 | 2009-02-01 | 2018-01-02 |
| Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies double-unit umbilical cord blood transplantation, cytogenetic analysis, bone marrow aspiration - Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission | Phase 2 | Completed | Case Comprehensive Cancer Center | 14 | 2007-09-01 | 2019-01-23 |
| Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia ifosfamide, etoposide, rituximab - B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Burkitt Lymphoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 82 | 2003-11-01 | 2013-10-08 |
| Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia allopurinol, cyclophosphamide, daunorubicin hydrochloride - Acute Undifferentiated Leukemia, B-cell Adult Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 302 | 2003-06-01 | 2022-05-03 |
| Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation therapeutic allogeneic lymphocytes, aldesleukin, peripheral blood stem cell transplantation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2002-09-01 | 2017-03-29 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Burkitt Lymphoma (4) · Dendritic Cell Sarcoma, Interdigitating (3) · Lymphoma, Large B-Cell, Diffuse (3) · Congenital Abnormalities (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myeloid, Acute (2) · Leukemia, Myelomonocytic, Chronic (2) · Lymphoma, B-Cell, Marginal Zone (2) · Lymphoma, Follicular (2) · Lymphoma, Large-Cell, Immunoblastic (2) · Lymphoma, Mantle-Cell (2) · Lymphoma, Non-Hodgkin (2) · Waldenstrom Macroglobulinemia (2) · Anemia, Refractory, with Excess of Blasts (1)
Hemic and Lymphatic Diseases (7) · Immune System Diseases (7) · Immunoproliferative Disorders (7) · Lymphatic Diseases (7) · Lymphoproliferative Disorders (7) · Neoplasms (7) · Neoplasms by Histologic Type (7) · Hematologic Diseases (6) · Leukemia (6) · Leukemia, Lymphoid (6) · DNA Virus Infections (4) · Epstein-Barr Virus Infections (4) · Herpesviridae Infections (4) · Infections (4) · Lymphoma (4)
Cyclophosphamide (3) · Cytarabine (3) · Filgrastim (3) · Methotrexate (3) · Asparaginase (2) · Cytogenetic Analysis (2) · Flow Cytometry (2) · Leucovorin (2) · Peripheral Blood Stem Cell Transplantation (2) · Rituximab (2) · Vincristine (2) · Acyclovir (1) · Alemtuzumab (1) · Allopurinol (1) · Antilymphocyte Serum (1)
National Cancer Institute (NCI) (3) · Fred Hutchinson Cancer Center (2) · Case Comprehensive Cancer Center (1) · Medical College of Wisconsin (1)
United States (7) · Australia (1) · Canada (1) · Puerto Rico (1)
Brenda Cooper, MD (1) · David Maloney (1) · Merav Bar (1) · Rachel Phelan, MD, MPH (1) · Terzah Horton, MD PhD (1) · Timothy Griffin (1) · Wendy Stock (1)
PMID 28419486, PMID 30957229, PMID 31481800, PMID 41671463
U10CA098543 (2), P01CA018029 (1), P01CA078902 (1), P30CA015704 (1), U10CA031946 (1), U10CA180886 (1)