4 completed, 1 unknown. 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 1 | Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Antimalarials: new trials by email Literature Review of Antimalarials trials Research Report on Antimalarials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Practices for Treating Severe Malaria Caused by P. Falciparum Malaria, Falciparum, Plasmodium Falciparum | Completed | Centre Hospitalier de Saint-Denis | 77 | 2024-05-01 | 2025-06-18 | |
| Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum MMV367 3mg, P. falciparum IBSM infection, MMV367 5mg - Infections, Vector Borne Diseases | Phase 1 | Completed | Medicines for Malaria Venture | 12 | 2023-08-01 | 2025-12-10 |
| Low-dose Hydroxychloroquine and Bromhexine: a Novel Regimen for COVID-19 Prophylaxis in Healthcare Professionals Hydroxychloroquine Sulfate, Bromhexine 8 MG - Hydroxychloroquine, Antimalarials | Early Phase 1 | Unknown | Instituto Nacional de Rehabilitacion | 214 | 2021-02-01 | 2021-06-29 |
| The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial Resistance Falciparum Malaria, Antimalarials | Completed | Tropical Medicine Research Institute | 100 | 2006-10-01 | 2008-03-26 | |
| Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia Artesunate - Malaria,Falciparum, Malaria | Phase 3 | Completed | Centro Internacional de Entrenamiento e Investigaciones Médicas | 360 | 2000-04-01 | 2006-09-20 |
Malaria, Falciparum (4) · Malaria (2) · COVID-19 (1) · Infections (1) · Inflammation (1) · Parasitemia (1) · Parasitic Diseases (1) · Pathologic Processes (1) · Protozoan Infections (1) · Systemic Inflammatory Response Syndrome (1) · Vector Borne Diseases (1)
Infections (4) · Mosquito-Borne Diseases (4) · Parasitic Diseases (3) · Protozoan Infections (3) · Vector Borne Diseases (3) · Malaria (2) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Lung Diseases (1) · Nidovirales Infections (1) · Pathological Conditions, Signs and Symptoms (1) · Pneumonia (1) · Pneumonia, Viral (1) · RNA Virus Infections (1) · Respiratory Tract Diseases (1)
Artesunate (1) · Bromhexine (1) · Hydroxychloroquine (1)
Centre Hospitalier de Saint-Denis (1) · Centro Internacional de Entrenamiento e Investigaciones Médicas (1) · Instituto Nacional de Rehabilitacion (1) · Medicines for Malaria Venture (1) · Tropical Medicine Research Institute (1)
Australia (1) · Colombia (1) · France (1) · Mexico (1) · Sudan (1)
Badria B El-Sayed, PhD (1) · Benoit Bestgen, PhD (1) · Colin Sutherland, PhD. (1) · Julio Granados-Montiel, MD, PhD (1) · Lyda Osorio, MD PhD (1)
PMID 18945956, PMID 25321315, PMID 27183377, PMID 28621712, PMID 32020029, PMID 32091533, PMID 32094336, PMID 32109013, PMID 32142651, PMID 32150618, PMID 32167747, PMID 32228809, PMID 32294342, PMID 32379955, PMID 32475230, PMID 33108255, PMID 33155953, PMID 33519466, PMID 33558079, PMID 34344672