4 completed. 4 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 4 |
| Phase 2 | 2 | Completed 2 |
Follow Anemia, Diamond-Blackfan: new trials by email Literature Review of Anemia, Diamond-Blackfan trials Research Report on Anemia, Diamond-Blackfan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload Deferasirox - Thalassemia, Sickle Cell Disease | Phase 3 | Completed | Novartis Pharmaceuticals | 1683 | 2005-10-01 | 2011-06-07 |
| A Study Assessing the Efficacy and Safety of Deferasirox in Patients With Transfusion-dependent Iron Overload Deferasirox - Transfusion-dependent Iron Overload | Phase 3 | Completed | Novartis Pharmaceuticals | 1784 | 2005-04-01 | 2020-02-11 |
| Stem Cell Transplant for Hemoglobinopathy Busulfan, Fludarabine, ATG, TLI, Busulfan, Cyclophosphamide, ATG, GCSF, Campath, Fludarabine, Cyclophosphamide - Sickle Cell Disease, Thalassemia | Phase 2 / Phase 3 | Completed | Masonic Cancer Center, University of Minnesota | 22 | 2002-06-01 | 2020-02-27 |
| Stem Cell Transplant for Bone Marrow Failure Syndromes Stem cell transplant, Fludarabine monophosphate, Total lymphoid irradiation - Diamond-Blackfan Anemia, Kostmann's Neutropenia | Phase 2 / Phase 3 | Completed | Masonic Cancer Center, University of Minnesota | 10 | 2000-06-01 | 2017-12-28 |
Thalassemia (3) · Anemia (2) · Anemia, Sickle Cell (2) · Shwachman-Diamond Syndrome (2) · Bone Marrow Failure Disorders (1) · Myelodysplastic Syndromes (1) · Neutropenia, Severe Congenital, Autosomal Recessive 3 (1) · Primary Myelofibrosis (1)
Anemia, Aplastic (4) · Anemia, Hypoplastic, Congenital (4) · Bone Marrow Diseases (4) · Congenital Bone Marrow Failure Syndromes (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Genetic Diseases, Inborn (4) · Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Red-Cell Aplasia, Pure (4) · Anemia, Hemolytic (3) · Anemia, Hemolytic, Congenital (3) · Bone Marrow Failure Disorders (3) · Hemoglobinopathies (3) · Anemia (2) · Digestive System Diseases (2)
Antilymphocyte Serum (2) · Busulfan (2) · Deferasirox (2) · fludarabine phosphate (2) · Alemtuzumab (1) · Bone Marrow Transplantation (1) · Cyclophosphamide (1) · Granulocyte Colony-Stimulating Factor (1) · Stem Cell Transplantation (1) · Whole-Body Irradiation (1) · fludarabine (1)
Masonic Cancer Center, University of Minnesota (2) · Novartis Pharmaceuticals (2)
United States (3) · Belgium (2) · Germany (2) · Greece (2) · Italy (2) · Netherlands (2) · Spain (2) · Taiwan (2) · Thailand (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Australia (1) · Austria (1) · Canada (1) · China (1)
Angela Smith, MD (1) · Paul Orchard, MD (1)
PMID 19951979, PMID 19996412, PMID 20566896, PMID 21071497, PMID 23585526, PMID 25691036
2004 (1)