6 active not recruiting. 6 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Active not recruiting 6 |
| Phase 2 | 6 | Active not recruiting 6 |
Follow Anemia, Aplastic: new trials by email Literature Review of Anemia, Aplastic trials Research Report on Anemia, Aplastic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure Ruxolitinib - Severe Aplastic Anemia, Single Lineage Cytopenias, T-LGL | Phase 1 / Phase 2 | Active not recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 13 | 2024-02-20 | 2026-10-14 |
| Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant Anti-Thymocyte Globulin, Cyclophosphamide, Cytokine-treated Veto Cells - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 1 / Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 16 | 2019-08-08 | 2026-06-11 |
| Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Fludarabine Phosphate - Acute Myeloid Leukemia in Remission, Adult Acute Lymphoblastic Leukemia in Complete Remission | Phase 1 / Phase 2 | Active not recruiting | Roswell Park Cancer Institute | 35 | 2017-08-09 | 2026-04-14 |
| Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant BPX-501 T cells, Rimiducid - Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child | Phase 1 / Phase 2 | Active not recruiting | Bellicum Pharmaceuticals | 120 | 2014-04-01 | 2022-07-12 |
| CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation CD34 Stem Cell Selection Therapy - Bone Marrow Failure Syndrome, Severe Aplastic Anemia | Phase 1 / Phase 2 | Active not recruiting | Diane George | 37 | 2013-03-01 | 2025-08-14 |
| Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia Cohort 1: hATG, CsA, EPAG Day 14 to Month 6, Cohort 2: hATG, CsA, EPAG Day 14 to Month 3, Cohort 3: hATG, CsA (dose reduced), EPAG day 1 to month 6 - Severe Aplastic Anemia | Phase 1 / Phase 2 | Active not recruiting | National Heart, Lung, and Blood Institute (NHLBI) | 207 | 2012-07-02 | 2026-04-13 |
Lymphoma, Non-Hodgkin (3) · Myelodysplastic Syndromes (3) · Bone Marrow Failure Disorders (2) · Hodgkin Disease (2) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Leukemia, Myeloid, Acute (2) · Multiple Myeloma (2) · Myeloproliferative Disorders (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Primary Immunodeficiency Diseases (2) · Acquired Immunodeficiency Syndrome (1) · Anemia, Diamond-Blackfan (1) · Anemia, Sickle Cell (1) · Autoimmune Diseases (1)
Anemia (6) · Bone Marrow Diseases (6) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Immune System Diseases (5) · Bone Marrow Failure Disorders (4) · Immunoproliferative Disorders (4) · Lymphatic Diseases (4) · Lymphoproliferative Disorders (4) · Leukemia, Myeloid (3) · Lymphoma (3) · Neoplasms (3) · Neoplasms by Histologic Type (3) · Blood Protein Disorders (2) · Cardiovascular Diseases (2)
Cyclophosphamide (2) · Whole-Body Irradiation (2) · AP 1903 reagent (1) · Antilymphocyte Serum (1) · Cyclosporine (1) · Melphalan (1) · Mycophenolic Acid (1) · Peripheral Blood Stem Cell Transplantation (1) · Sirolimus (1) · eltrombopag (1) · fludarabine (1) · fludarabine phosphate (1) · ruxolitinib (1)
National Heart, Lung, and Blood Institute (NHLBI) (2) · Bellicum Pharmaceuticals (1) · Diane George (1) · M.D. Anderson Cancer Center (1) · Roswell Park Cancer Institute (1)
United States (6)
Bhavisha Patel, M.D. (1) · Diane George, MD (1) · Maureen Ross (1) · Neal S Young, M.D. (1) · Richard E Champlin (1)
PMID 26354756, PMID 29419434, PMID 29674506, PMID 29958797, PMID 33410523, PMID 33910334, PMID 34525188, PMID 34724566