11 completed. 11 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 11 |
| Phase 2 | 1 | Completed 1 |
Follow Ancylostomiasis: new trials by email Literature Review of Ancylostomiasis trials Research Report on Ancylostomiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults Na-GST-1, CPG 10104 - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 24 | 2018-02-01 | 2021-01-13 |
| Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children Na-GST-1/Alhydrogel, Na-APR-1 (M74)/Alhydrogel, Hepatitis B Vaccine - Hookworm Disease, Hookworm Infection | Phase 1 | Completed | Baylor College of Medicine | 60 | 2017-01-01 | 2025-01-13 |
| Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults Na-GST-1/Alhydrogel plus GLA-AF, Na-APR-1 (M74)/Alhydrogel, Na-APR-1 (M74)/Alhydrogel plus GLA-AF - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 60 | 2016-01-01 | 2019-12-03 |
| Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults Na-APR-1 (M74)/Alhydrogel®, Na-GST-1/Alhydrogel®, Hepatitis B vaccine - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 32 | 2014-11-01 | 2017-05-31 |
| Safety and Immunogenicity Study of Na-GST-1 With or Without CpG Na-GST-1/Alhydrogel®, CpG 10104 - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 24 | 2014-10-01 | 2025-07-04 |
| Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults Na-APR-1 (M74)/Alhydrogel®, Gluco-Pyranosylphospho-Lipid A Aqueous Formulation - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 40 | 2013-09-01 | 2019-07-31 |
| Desensitising Celiac Disease Patients With the Human Hookworm Necator americanus - Celiac Disease | Phase 1 / Phase 2 | Completed | The Prince Charles Hospital | 12 | 2012-08-01 | 2014-10-20 |
| Impact of Health Education on School Children Health Education package - Intestinal Helminthiasis | Phase 1 | Completed | University of Malaya | 317 | 2012-07-01 | 2014-06-24 |
| Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel Adjuvant 10 μg Na-GST-1/Alhydrogel, 30 μg Na-GST-1/Alhydrogel, 100 μg Na-GST-1/Alhydrogel - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 40 | 2012-05-01 | 2025-01-06 |
| Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults 10 μg Na-GST-1/Alhydrogel, 30 μg Na-GST-1/Alhydrogel, 100 μg Na-GST-1/Alhydrogel - Hookworm Infection, Hookworm Disease | Phase 1 | Completed | Baylor College of Medicine | 102 | 2011-11-01 | 2017-05-31 |
| Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection Na-ASP-2/Alhydrogel Hookworm Vaccine, Saline placebo - Hookworm Infection | Phase 1 | Completed | Baylor College of Medicine | 36 | 2005-04-01 | 2017-05-31 |
Hookworm Infections (9) · Anemia, Iron-Deficiency (6) · Neglected Diseases (4) · Celiac Disease (1) · Health Education (1) · Intestinal helminthiasis (1)
Helminthiasis (11) · Infections (11) · Nematode Infections (11) · Parasitic Diseases (11) · Secernentea Infections (11) · Strongylida Infections (11) · Metabolic Diseases (7) · Nutritional and Metabolic Diseases (7) · Anemia (6) · Anemia, Hypochromic (6) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Iron Deficiencies (6) · Iron Metabolism Disorders (6) · Disease Attributes (4)
Hepatitis B Vaccines (2) · ASP-1 protein, Necator americanus (1) · CPG-oligonucleotide (1) · D-Worm (1) · GLA-AF adjuvant (1) · Granuflex E (1)
Baylor College of Medicine (9) · The Prince Charles Hospital (1) · University of Malaya (1)
United States (4) · Gabon (3) · Brazil (2) · Australia (1) · Malaysia (1)
David Diemert, MD (4) · Ayola Adegnika, MD (3) · Ahmed K. Al-Delaimy, MSc (1) · Alexander Loukas, PhD (1) · David J Diemert, MD (1) · Dianne Jones, BAppSc (1) · Gary Simon, M.D., Ph.D (1) · Hesham M Al-Mekhlafi, PhD (1) · John Croese, MD (1) · Rodrigo Correa-Oliveira, PhD (1)
PMID 28464026, PMID 18396361, PMID 32926834, PMID 34597297, PMID 38513684