4 completed, 1 terminated, 1 unknown. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow Alpha Mannosidosis: new trials by email Literature Review of Alpha Mannosidosis trials Research Report on Alpha Mannosidosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dose Finding Study of Recombinant Human Alpha-mannosidase for the Treatment of Patients With Alpha-mannosidosis Lamazym - Alpha Mannosidosis | Phase 2 | Unknown | Zymenex A/S | 10 | 2011-01-01 | 2012-09-26 |
| Safety Study of Recombinant Human Alpha-mannosidase for the Treatment of Patients With Alpha-mannosidosis Lamazym - Alpha Mannosidosis | Phase 1 | Completed | Zymenex A/S | 10 | 2010-10-01 | 2020-08-03 |
| Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders Campath-1H, Cyclophosphamide, Busulfan - Mucopolysaccharidosis, Hurler Syndrome | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 46 | 2009-12-01 | 2018-02-05 |
| Longitudinal Studies of the Glycoproteinoses Non-interventional. - Aspartylglucosaminuria, Fucosidosis | Completed | Greenwood Genetic Center | 100 | 2009-08-01 | 2023-09-13 | |
| Hematopoietic Stem Cell Transplantation (HCT) for Inborn Errors of Metabolism Stem Cell Transplantation, Cyclophosphamide, Campath-1H - Hurler's Syndrome, Maroteaux-Lamy Syndrome | Phase 2 | Terminated | Masonic Cancer Center, University of Minnesota | 18 | 2008-03-01 | 2017-12-28 |
| The Natural History of Alpha-Mannosidosis Alpha Mannosidosis | Completed | Zymenex A/S | 45 | 2007-05-01 | 2020-08-03 |
alpha-Mannosidosis (6) · Aspartylglucosaminuria (3) · Fucosidosis (3) · Leukodystrophy, Globoid Cell (2) · Leukodystrophy, Metachromatic (2) · Mucopolysaccharidosis I (2) · Mucopolysaccharidosis VI (2) · Mucopolysaccharidosis VII (2) · Peroxisomal Disorders (2) · Sphingolipidoses (2) · Adrenoleukodystrophy (1) · Dysostoses (1) · Glycoprotein Storage Disease (1) · Lysosomal Storage Diseases (1) · Metabolic Diseases (1)
Carbohydrate Metabolism, Inborn Errors (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Mannosidase Deficiency Diseases (6) · Nutritional and Metabolic Diseases (6) · Lysosomal Storage Diseases (5) · Metabolic Diseases (5) · Metabolism, Inborn Errors (5) · Brain Diseases (3) · Brain Diseases, Metabolic (3) · Brain Diseases, Metabolic, Inborn (3) · Central Nervous System Diseases (3) · Lysosomal Storage Diseases, Nervous System (3) · Nervous System Diseases (3) · Bone Diseases (2)
Alemtuzumab (2) · Busulfan (2) · Cyclophosphamide (2) · Stem Cell Transplantation (2) · Bone Marrow Transplantation (1) · Cyclosporine (1) · Mycophenolic Acid (1)
Zymenex A/S (3) · Masonic Cancer Center, University of Minnesota (2) · Greenwood Genetic Center (1)
United States (3) · Czechia (1) · Denmark (1) · Germany (1) · Norway (1) · United Kingdom (1)
Allan M. Lund, MD (2) · Jens Fogh (2) · Paul Orchard, MD (2) · Dag Malm, MD (1) · Ed Wraith, MD (1) · Jiri Zeman, MD (1) · Michael Beck, MD (1) · Sara Cathey, MD (1)
PMID 26048034, PMID 19617216, PMID 21586746, PMID 23494656, PMID 23786919