17 recruiting, 14 completed, 10 unknown, 6 not yet recruiting. 23 Phase 1, 19 Phase 2, 14 Not applicable, 3 Early Phase 1.
Follow Advanced Lung Cancer: new trials by email Literature Review of Advanced Lung Cancer trials Research Report on Advanced Lung Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer Dyspnea Intervention, Enhanced Usual Care - Advanced Lung Cancer, Dyspnea | Not applicable | Recruiting | Massachusetts General Hospital | 420 | 2026-11-01 | 2026-10-19 |
| A Pilot Study of the VosCryoTM Breathalyser in Lung Cancer Expiratory Breath Condensate Collection - Advanced Lung Cancer | Not yet recruiting | Sheffield Teaching Hospitals NHS Foundation Trust | 24 | 2026-09-01 | 2026-07-14 | |
| A First-in-human (FIH), Open-Label, Dose Escalation and Expansion Cohorts Study of MC002 MC002（ADC） - Advanced Esophageal Cancer, Advanced Lung Cancer | Phase 1 | Not yet recruiting | Hangzhou MacroLink Biopharmaceutical LLC | 143 | 2026-09-01 | 2026-07-27 |
| Tier Palliative Care For Patients With Advanced Heart Failure or Cancer Tier-Palliative Care, Community Health Worker - Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 400 | 2026-07-10 | 2026-09-14 |
| A Clinical Study GK01 Cell Injection in Subjects With Advanced Lung Cancer GK01 Injection - Advanced Lung Cancer | Early Phase 1 | Not yet recruiting | Beijing Geekgene Technology Co., LTD | 10 | 2026-07-01 | 2026-06-29 |
| A Clinical Trial on the Efficacy and Safety of TQB6411 for Injection TQB6411 for Injection - Advanced Lung Cancer | Phase 1 / Phase 2 | Recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 465 | 2026-02-26 | 2026-09-08 |
| A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer Survivors PROMOTE Digital Health App Intervention, Enhanced Usual Care - Advanced Lung Cancer, Physical Function | Not applicable | Recruiting | Massachusetts General Hospital | 250 | 2026-02-06 | 2026-03-19 |
| A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer JS212 for Injection, JS207 for Injection, Toripalimab - Advanced Lung Cancer | Phase 2 | Recruiting | Shanghai Junshi Bioscience Co., Ltd. | 864 | 2026-01-23 | 2026-05-18 |
| The Efficacy and Safety of ARNI on the Outcome of Advanced Lung Cancer With Concurrent Hypertension ARNI, Anti-hypertensive drugs except ARNI - Advanced Lung Cancer | Phase 2 | Not yet recruiting | Shanghai Chest Hospital | 200 | 2026-01-01 | 2025-12-03 |
| A Clinical Study of BT02 in Treating Patients With Advanced Lung Cancer BT02 - Advanced Malignant Solid Tumor, Advanced Lung Cancer | Phase 1 | Not yet recruiting | Biotroy Therapeutics | 58 | 2025-08-01 | 2025-08-07 |
| Evaluation of the Effectiveness of Managing Chemotherapy Side Effects Using ePRO and a Standardized Telenursing Program for Cancer Patients Standardized Telenursing, Smart Cancer Care Plus - Early Gastric Cancer, Advanced Gastric Cancer | Not applicable | Recruiting | Ulsan University Hospital | 414 | 2025-07-09 | 2026-02-12 |
| Engage Psychosocial Intervention for Cancer Symptoms ENGAGE, Supportive Care - Advanced Breast Cancer, Advanced Prostate Cancer | Not applicable | Recruiting | Duke University | 190 | 2025-06-11 | 2026-03-16 |
| A Study of MHB036C Combined With Anti-tumor Therapies in Patients With Advanced Lung Cancer MHB036C for Injection, MHB039A for Injection, Furmonertinib - Advanced Lung Cancer | Phase 1 / Phase 2 | Recruiting | Minghui Pharmaceutical (Hangzhou) Ltd | 300 | 2025-05-09 | 2025-11-17 |
| Targeted Anti-CEA CAR-T Immunotherapy for Advanced Lung Cancer Targeted CEA CAR-T - Advanced Lung Cancer | Phase 1 | Recruiting | Chongqing Precision Biotech Co., Ltd | 60 | 2025-05-08 | 2025-05-28 |
| A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer BNT324, BNT327 - Advanced Lung Cancer | Phase 1 / Phase 2 | Recruiting | BioNTech SE | 594 | 2025-05-02 | 2026-08-26 |
| Clinical Study on Chimeric Antigen Receptor T Lymphocyte (CAR-T) Targeting CEA for the Treatment of CEA - Positive Advanced Lung Cancer Targeted CEA CAR-T - Advanced Lung Cancer | Phase 1 | Recruiting | Chongqing Precision Biotech Co., Ltd | 60 | 2025-04-28 | 2025-06-04 |
| Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model, Oncology Case Manager Care and Usual Care - Non-Small Cell Lung Cancer, Advanced Lung Cancer | Not applicable | Recruiting | National Taiwan University Hospital | 120 | 2025-04-08 | 2026-07-16 |
| Anti-CEA CAR-T for Advanced CEA-Positive Lung Carcinoma Targeted CEA CAR-T - Advanced Lung Cancer | Phase 1 | Recruiting | Chongqing Precision Biotech Co., Ltd | 60 | 2025-03-24 | 2025-04-03 |
| Inhaled mRNA Tumor-associated Antigen Dry Powder Vaccine in Advanced Lung Cancer and Lung Metastasis of Solid Tumors. BMD006 monotreatment, BMD006 in combination with PD-1 antibody, BMD006 in combination with PD-1/VEGF antibody - Advanced Lung Cancer, Lung Metastasis | Early Phase 1 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 83 | 2025-02-24 | 2026-01-13 |
| Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer Tier-Palliative Care - Advanced Heart Failure, Advanced Non-Colorectal Gastointestinal Cancer | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 60 | 2025-01-31 | 2026-10-13 |
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Lung Neoplasms (12) · Carcinoma, Non-Small-Cell Lung (9) · Breast Neoplasms (4) · Small Cell Lung Carcinoma (3) · Colorectal Neoplasms (2) · Motor Activity (2) · Neoplasm Metastasis (2) · Stomach Neoplasms (2) · Adenocarcinoma (1) · Adenocarcinoma of Lung (1) · Agnosia (1) · Brain Neoplasms (1) · Carcinoma, Basal Cell (1) · Carcinoma, Merkel Cell (1) · Carcinoma, Renal Cell (1)
Neoplasms (20) · Neoplasms by Site (19) · Respiratory Tract Diseases (19) · Lung Diseases (18) · Respiratory Tract Neoplasms (18) · Thoracic Neoplasms (18) · Bronchial Neoplasms (9) · Carcinoma, Bronchogenic (9) · Lung Neoplasms (6) · Pathological Conditions, Signs and Symptoms (6) · Behavior (4) · Breast Diseases (4) · Signs and Symptoms (4) · Skin Diseases (4) · Skin and Connective Tissue Diseases (4)
Injections (4) · toripalimab (3) · Carboplatin (2) · Drug Therapy (2) · Exercise (2) · sintilimab (2) · AZD 6244 (1) · Afatinib (1) · Bevacizumab (1) · Chlorogenic Acid (1) · Cisplatin (1) · Community Health Workers (1) · Crizotinib (1) · Cryotherapy (1) · Docetaxel (1)
Chongqing Precision Biotech Co., Ltd (4) · Massachusetts General Hospital (3) · Shanghai Junshi Bioscience Co., Ltd. (3) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (2) · Icahn School of Medicine at Mount Sinai (2) · Innovent Biologics (Suzhou) Co. Ltd. (2) · National Taiwan University Hospital (2) · Shanghai Chest Hospital (2) · Shanxi Province Cancer Hospital (2) · Beijing Geekgene Technology Co., LTD (1) · BioNTech SE (1) · Biotroy Therapeutics (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Chulabhorn Cancer Center (1)
China (26) · United States (10) · France (3) · Spain (3) · Taiwan (3) · United Kingdom (3) · Australia (2) · Italy (2) · South Korea (2) · Thailand (2) · Brazil (1) · Canada (1) · Germany (1) · Mongolia (1) · Poland (1)
Qingjuan Li, MD (2) · Ying Cheng (2) · Baohui Han, MD, PhD (1) · Don L. Gibbons, MD, PHD (1) · Gregrory Riely, MD, PhD (1) · Huajun Jin (1) · Ji Hyung Hong, Doctor of Philoshophy (1) · Jiangtao Wang (1) · Jibing Chen, Doctor (1) · Jun Zhao, MD (1) · Jung Hun Kang, Doctor of Philoshophy (1) · Keun Soek Lee, Doctor of Philoshophy (1) · Laura A Petrillo, MD (1) · Laura Gelfman (1)
PMID 21538097, PMID 22888384, PMID 24641382, PMID 25376224, PMID 25876560, PMID 28573475, PMID 33581739, PMID 35844029, PMID 39938469, PMID 40614321, PMID 40834926, PMID 41666769
2023 (1), R01CA291768 (1), R01CA292902 (1), R56NR020624 (1)