5 completed. 5 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 2 | Completed 2 |
Follow Adrenocortical Hyperfunction: new trials by email Literature Review of Adrenocortical Hyperfunction trials Research Report on Adrenocortical Hyperfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome atumelnant - Cushing Syndrome, Cushing Disease | Phase 1 / Phase 2 | Completed | Crinetics Pharmaceuticals Inc. | 19 | 2023-10-12 | 2026-10-14 |
| Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants Dabigatran Etexilate, Relacorilant - Cushing Syndrome, Neoplasms | Phase 1 | Completed | Corcept Therapeutics | 30 | 2022-05-25 | 2023-02-09 |
| Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol) Relacorilant, Pembrolizumab - Adrenocortical Carcinoma | Phase 1 | Completed | Corcept Therapeutics | 15 | 2020-09-30 | 2024-02-23 |
| Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia Subcutaneous hydrocortisone - Congenital Adrenal Hyperplasia, Hyperplasia | Phase 1 | Completed | University of Minnesota | 11 | 2019-01-01 | 2025-06-25 |
| Mifepristone Effects on Glucose Intolerance in Obese/Overweight Adults Mifepristone, Placebo - Endocrine Disease, Diabetes | Phase 1 / Phase 2 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 19 | 2011-11-29 | 2021-04-14 |
Cushing Syndrome (4) · ACTH Syndrome, Ectopic (2) · Adrenal Gland Diseases (2) · Endocrine System Diseases (2) · Glucose Intolerance (2) · Adrenal Cortex Neoplasms (1) · Adrenal Hyperplasia, Congenital (1) · Adrenocortical Carcinoma (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Disorders of Sex Development (1) · Genetic Diseases, Inborn (1) · Hyperglycemia (1)
Adrenal Gland Diseases (3) · Endocrine System Diseases (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Glucose Metabolism Disorders (2) · Neoplasms (2) · Paraneoplastic Endocrine Syndromes (2) · Paraneoplastic Syndromes (2) · Pathological Conditions, Signs and Symptoms (2) · Adenocarcinoma (1) · Adrenal Cortex Diseases (1) · Adrenal Gland Neoplasms (1) · Adrenogenital Syndrome (1) · Brain Diseases (1)
relacorilant (2) · Dabigatran (1) · Mifepristone (1) · pembrolizumab (1)
Corcept Therapeutics (2) · Crinetics Pharmaceuticals Inc. (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · University of Minnesota (1)
United States (5)
Andreas G Moraitis, MD (1) · Joseph Custodio, PhD (1) · Kyriaki Sarafoglou, MD (1) · Lynnette K Nieman, M.D. (1)
ZIADK075121 (1)