12 completed. 12 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 12 | Completed 12 |
| Phase 2 | 2 | Completed 2 |
Follow Adrenal Cortex Diseases: new trials by email Literature Review of Adrenal Cortex Diseases trials Research Report on Adrenal Cortex Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol) Relacorilant, Pembrolizumab - Adrenocortical Carcinoma | Phase 1 | Completed | Corcept Therapeutics | 15 | 2020-09-30 | 2024-02-23 |
| Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma ATR-101 - Adrenocortical Carcinoma, Adrenal Cancer | Phase 1 | Completed | Millendo Therapeutics, Inc. | 63 | 2013-08-13 | 2017-11-06 |
| Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor) Avelumab - Solid Tumors | Phase 1 | Completed | EMD Serono Research & Development Institute, Inc. | 1756 | 2013-01-31 | 2021-12-20 |
| A Dose Finding Study of TKM-080301 Infusion in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients TKM-080301 - Cancer, Neuroendocrine Tumors | Phase 1 / Phase 2 | Completed | Arbutus Biopharma Corporation | 68 | 2010-12-01 | 2019-01-16 |
| Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features Seneca Valley virus-001, cyclophosphamide, laboratory biomarker analysis - Adrenocortical Carcinoma, Gastrointestinal Carcinoid Tumor | Phase 1 | Completed | Children's Oncology Group | 22 | 2009-09-01 | 2014-01-30 |
| Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac Surgery Cosyntropin - Adrenal Cortex Diseases, Infant Morbidity | Phase 1 | Completed | Mayo Clinic | 35 | 2009-03-01 | 2014-06-16 |
| Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy 123I-Iodometomidate - Adrenal Tumor, Adrenocortical Carcinoma | Phase 1 / Phase 2 | Completed | University of Wuerzburg | 2007-03-01 | 2010-08-18 | |
| Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer CHPP of Cisplatin, Abdominal Surgery - Peritoneal Neoplasms, Retroperitoneal Neoplasms | Phase 1 | Completed | M.D. Anderson Cancer Center | 10 | 2007-02-01 | 2012-04-02 |
| MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma entinostat - Cancer | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 75 | 2001-03-01 | 2012-03-15 |
| Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer trastuzumab, tipifarnib - Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 24 | 2000-06-01 | 2013-02-11 |
| Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu recombinant interleukin-12, ABI-007/carboplatin/trastuzumab - Advanced Adult Primary Liver Cancer, Anaplastic Thyroid Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 15 | 1999-08-01 | 2013-02-28 |
| Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors doxorubicin hydrochloride, suramin - Adrenocortical Carcinoma, Breast Cancer | Phase 1 | Completed | Mayo Clinic | 1997-10-01 | 2011-08-03 |
Adrenocortical Carcinoma (11) · Breast Neoplasms (5) · Neoplasms (5) · Carcinoma, Non-Small-Cell Lung (4) · Carcinoma, Renal Cell (4) · Colonic Neoplasms (4) · Prostatic Neoplasms (4) · Urinary Bladder Neoplasms (4) · Anus Neoplasms (3) · Appendiceal Neoplasms (3) · Bile Duct Neoplasms (3) · Breast Neoplasms, Male (3) · Carcinoma, Hepatocellular (3) · Endometrial Neoplasms (3) · Esophageal Neoplasms (3)
Adrenal Gland Diseases (11) · Carcinoma (11) · Endocrine Gland Neoplasms (11) · Endocrine System Diseases (11) · Neoplasms by Histologic Type (11) · Neoplasms by Site (11) · Neoplasms, Glandular and Epithelial (11) · Adenocarcinoma (10) · Adrenal Cortex Neoplasms (10) · Adrenal Gland Neoplasms (9) · Male Urogenital Diseases (7) · Neoplasms, Germ Cell and Embryonal (7) · Neoplasms, Nerve Tissue (7) · Neuroectodermal Tumors (7)
Trastuzumab (2) · Adrenocorticotropic Hormone (1) · Cisplatin (1) · Cosyntropin (1) · Cyclophosphamide (1) · Cytoreduction Surgical Procedures (1) · Doxorubicin (1) · Interleukin-12 (1) · Interleukin-12 Subunit p35 (1) · N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea hydrochloride (1) · Suramin (1) · TKM-080301 (1) · avelumab (1) · entinostat (1) · iodophenyl metomidate (1)
Mayo Clinic (2) · National Cancer Institute (NCI) (2) · Arbutus Biopharma Corporation (1) · Children's Oncology Group (1) · Corcept Therapeutics (1) · EMD Serono Research & Development Institute, Inc. (1) · M.D. Anderson Cancer Center (1) · Millendo Therapeutics, Inc. (1) · National Institutes of Health Clinical Center (CC) (1) · University of Wuerzburg (1)
United States (11) · Germany (3) · Belgium (1) · Czechia (1) · France (1) · Poland (1) · South Korea (1) · Taiwan (1) · United Kingdom (1)
Alex A. Adjei, MD, PhD (1) · Andrea Hayes-Jordan, MD (1) · Andreas G Moraitis, MD (1) · Anthony W. Tolcher, MD (1) · Christoph Reiners, MD (1) · Mark Kowalski, MD (1) · Michael J. Burke, MD (1) · Sheri S Crow, MD,MS (1) · Shivaani Kummar, MD (1) · William Carson (1)
PMID 26666256, PMID 28239472, PMID 29217288, PMID 30348224, PMID 30605211, PMID 30651126, PMID 30676622, PMID 30717797, PMID 31553054, PMID 31639039, PMID 31651359, PMID 31984451, PMID 32849281, PMID 32907924, PMID 33219092, PMID 34663640, PMID 36821354, PMID 37310790
P30CA015083 (1), U01CA069912 (1), U01CA076576 (1)