74 completed, 19 terminated, 7 active not recruiting, 7 unknown. 68 Phase 2, 26 Phase 1, 16 Not applicable, 9 Phase 3, 2 Early Phase 1.
Follow Adenocarcinoma of the Prostate: new trials by email Literature Review of Adenocarcinoma of the Prostate trials Research Report on Adenocarcinoma of the Prostate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RYZ711 Diagnostic Platform Study RYZ711, PSMA PET/CT - Prostate Cancer (Adenocarcinoma), Adenocarcinoma of the Prostate | Phase 1 / Phase 2 | Not yet recruiting | RayzeBio, Inc. | 116 | 2026-10-01 | 2026-10-19 |
| Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate - Recurrent Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 202 | 2026-08-04 | 2026-09-18 |
| Prediction of Lymph Node Invasion for Prostate Adenocarcinoma Adenocarcinoma of the Prostate | Unknown | University Hospital, Brest | 400 | 2021-01-01 | 2022-01-19 | |
| Prospective Prostate Cancer and Patient-reported Outcomes Registry standard of care - Prostate Cancer, Adenocarcinoma of the Prostate | Recruiting | Universitaire Ziekenhuizen KU Leuven | 5000 | 2020-10-01 | 2024-05-22 | |
| Evaluation of the Efficacy and the Safety of a Stereotaxic Prostatic Radiotherapy Delivered With Linac MRI, in Patients With Prostate Adenocarcinoma Stereotactic Radiotherapy with Linac MRI - Adenocarcinoma of the Prostate | Not applicable | Active not recruiting | Centre Georges Francois Leclerc | 68 | 2020-10-01 | 2024-02-13 |
| Clinical Trial of Selegiline Plus Docetaxel for the Treatment of Metastatic, Castrate-resistant Prostate Adenocarcinoma Selegiline, Docetaxel - Metastatic Castration-resistant Prostate Cancer, Adenocarcinoma of the Prostate | Phase 2 | Unknown | László Mangel | 110 | 2020-05-18 | 2020-10-14 |
| First in Man Clinical Study to Evaluate Safety and Tolerability of an Oncolytic Adenovirus in Prostate Cancer Patients. ORCA-010 - Adenocarcinoma of the Prostate | Phase 1 / Phase 2 | Unknown | Orca Therapeutics B.V. | 24 | 2019-11-12 | 2023-10-31 |
| Muscadine Plus (MPX) In Men With Prostate Cancer Muscadine Plus, Placebos - Adenocarcinoma of the Prostate | Phase 3 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 59 | 2018-10-30 | 2023-05-22 |
| Open- Label Trial of Sipuleucel-T Administered to Active Surveillance Patients for Newly Diagnosed Prostate Cancer sipuleucel-T - Adenocarcinoma of the Prostate | Phase 3 | Completed | Dendreon | 532 | 2018-10-18 | 2024-10-08 |
| Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8) Nivolumab, Degarelix, BMS-986253 - Prostate Cancer, Adenocarcinoma of the Prostate | Phase 1 / Phase 2 | Completed | Mark Stein | 59 | 2018-10-11 | 2026-10-15 |
| Dose-Escalated Proton Radiation Therapy for High-Risk Prostate Cancer HR-A, HR-B - Adenocarcinoma of the Prostate | Phase 2 | Active not recruiting | University of Florida | 100 | 2018-09-24 | 2026-08-13 |
| Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer Adaptive Androgen Deprivation Therapy (ADT), Abiraterone, Prednisone - Prostate Cancer, Stage IV Prostate Cancer | Early Phase 1 | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 17 | 2018-09-17 | 2025-12-04 |
| BrUOG 337: Olaparib Prior to Radical Prostatectomy For Advanced Prostate Cancer Defects in DNA Repair Genes Olaparib Pill, Prostatectomy - Prostate Cancer, Adenocarcinoma of the Prostate | Phase 2 | Terminated | Brown University | 1 | 2018-05-25 | 2025-07-08 |
| Trial of NanoPac® Focal Therapy in Subjects With Prostate Cancer NanoPac® - Adenocarcinoma of the Prostate | Phase 2 | Completed | NanOlogy, LLC | 16 | 2017-09-06 | 2019-08-20 |
| Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer Active CTC Assessment - Adenocarcinoma of the Prostate | Phase 3 | Terminated | Institute of Cancer Research, United Kingdom | 12 | 2017-01-11 | 2021-01-06 |
| Magnetic Resonance Guided Focal Stereotactic Body Radiation Therapy for Localized Prostate Cancer stereotactic radiosurgery, magnetic resonance imaging, quality-of-life assessment - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Not applicable | Completed | Case Comprehensive Cancer Center | 12 | 2016-02-16 | 2024-05-10 |
| Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer Enzalutamide, leuprolide acetate, goserelin acetate - Adenocarcinoma of the Prostate, Recurrent Prostate Cancer | Phase 2 | Completed | University of Colorado, Denver | 19 | 2015-11-11 | 2025-05-11 |
| Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer anti-PSMA monoclonal antibody MDX1201-A488, robot-assisted laparoscopic surgery, diffuse optical imaging - Adenocarcinoma of the Prostate, Stage IIB Prostate Cancer | Phase 1 | Completed | City of Hope Medical Center | 7 | 2015-10-05 | 2026-10-22 |
| Pilot Study of 18F-DCFPyL PET/CT in the Evaluation of Men With an Elevated PSA Following Radical Prostatectomy 18F-DCFPyL - Adenocarcinoma of the Prostate | Not applicable | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 50 | 2015-06-02 | 2020-01-31 |
| Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy Enzalutamide, SRT - Adenocarcinoma of the Prostate | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 86 | 2015-03-28 | 2025-10-28 |
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PMID 33270906, PMID 40932155, PMID 16515997, PMID 19349545, PMID 19483644, PMID 20818327, PMID 21106711, PMID 22044694, PMID 22932804, PMID 23652277, PMID 24048789, PMID 25819287, PMID 26510020, PMID 28178640, PMID 28692586, PMID 29476383, PMID 30575560, PMID 30682445, PMID 30703190, PMID 31196032, PMID 31806540, PMID 32205016, PMID 32226774, PMID 32349020, PMID 32850444, PMID 32974208, PMID 32994091, PMID 33084183, PMID 33496795, PMID 34028627, PMID 34604088, PMID 34616010, PMID 35189157, PMID 36358643, PMID 36367998, PMID 36996380, PMID 37623007, PMID 38833311, PMID 38992025, PMID 39663356, PMID 39671538, PMID 40325900, PMID 41346252, PMID 41802185
P30CA014089 (3), U10CA031946 (3), N01CM17101 (2), N01CN35158 (2), N01CN35159 (2), P30CA015704 (2), P30CA016672 (2), P30CA022453 (2), U01CA062491 (2), U10CA021115 (2), 2017 (1), 2019 (1), N01CM00038 (1), N01CM17102 (1), N01CM17104 (1)