6 terminated. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Terminated 6 |
| Phase 2 | 1 | Terminated 1 |
Follow Acute Lymphoblastic Leukemia: new trials by email Literature Review of Acute Lymphoblastic Leukemia trials Research Report on Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SPARK-ALL: Calaspargase Pegol in Adults With ALL Calaspargase pegol (S95015) - Acute Lymphoblastic Leukemia | Phase 2 / Phase 3 | Terminated | Institut de Recherches Internationales Servier | 42 | 2021-07-07 | 2026-10-29 |
| Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) Efprezimod alfa, Placebo, Methotrexate - Hematopoietic Stem Cell Transplantation, Acute Graft Versus Host Disease | Phase 3 | Terminated | Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 11 | 2021-01-05 | 2023-02-08 |
| Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer ATIR101, Cyclophosphamide, T-cell depleted HSCT from a related, haploidentical donor - Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia | Phase 3 | Terminated | Kiadis Pharma | 63 | 2017-11-29 | 2022-05-24 |
| PROCEDYTE: Depocyte® Administration (Liposomal Cytarabine) as Prophylaxis of Neuromeningeal Infiltration in Acute Lymphoblastic Leukemia DepoCyte - Acute Lymphoblastic Leukemia | Phase 3 | Terminated | PETHEMA Foundation | 7 | 2009-09-01 | 2015-05-08 |
| Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia Prednisone, Dexamethasone, Vincristine, Daunorubicin, PEG-L-asparaginase, L-asparaginase, Methotrexate, Idarubicin, Etoposide, Cyclophosphamide, Cytarabine, Mercaptopurine - Acute Lymphoblastic Leukemia | Phase 3 | Terminated | St. Jude Children's Research Hospital | 53 | 1998-07-01 | 2011-03-30 |
| Treatment of Childhood Acute Lymphoblastic Leukemia asparaginase (E. Coli), asparaginase (Erwina), dexrazoxane - Acute Lymphoblastic Leukemia | Phase 3 | Terminated | Dana-Farber Cancer Institute | 491 | 1996-01-01 | 2007-12-28 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (6) · Leukemia, Myeloid, Acute (2) · Myelodysplastic Syndromes (2) · Graft vs Host Disease (1) · Hematologic Neoplasms (1) · Leukemia (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1)
Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Immune System Diseases (6) · Immunoproliferative Disorders (6) · Leukemia, Lymphoid (6) · Lymphatic Diseases (6) · Lymphoproliferative Disorders (6) · Neoplasms (6) · Neoplasms by Histologic Type (6) · Leukemia (5) · Bone Marrow Diseases (2) · Leukemia, Myeloid (2) · Neoplasms by Site (1)
Asparaginase (2) · Cyclophosphamide (2) · Methotrexate (2) · Cytarabine (1) · Daunorubicin (1) · Dexamethasone (1) · Dexrazoxane (1) · Doxorubicin (1) · Etoposide (1) · Idarubicin (1) · Mercaptopurine (1) · Prednisone (1) · Radiation (1) · Sodium Chloride (1) · Tacrolimus (1)
Dana-Farber Cancer Institute (1) · Institut de Recherches Internationales Servier (1) · Kiadis Pharma (1) · Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · PETHEMA Foundation (1) · St. Jude Children's Research Hospital (1)
United States (5) · Canada (2) · Spain (2) · Belgium (1) · Croatia (1) · France (1) · Germany (1) · Israel (1) · Italy (1) · Netherlands (1) · Portugal (1) · Puerto Rico (1) · Sweden (1) · United Kingdom (1)
Ching-Hon Pui, MD (1) · Daniel J. DeAngelo, MD, PhD (1) · Denis Claude Roy, Prof MD (1) · Sancho Jose Manuel, Dr (1) · Stephan Mielke, Prof MD (1) · Stephen E. Sallan, MD (1)
PMID 15226337, PMID 15247354, PMID 20850381, PMID 33026184, PMID 41074700
2016 (1)