9 completed, 2 recruiting, 1 unknown. 5 Not applicable, 3 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Recruiting 2 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Abortion, Second Trimester: new trials by email Literature Review of Abortion, Second Trimester trials Research Report on Abortion, Second Trimester
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cervical Preparation for Same-Day Dilation & Evacuation Transcervical single-balloon catheter, Synthetic osmotic dilators - Abortion, Second Trimester, Procedural Pain | Not applicable | Recruiting | Boston Medical Center | 32 | 2025-06-12 | 2026-06-30 |
| Foley Balloon for Cervical Preparation Before Dilation and Evacuation Foley Balloon Catheter, Misoprostol, Laminaria - Abortion, Second Trimester, Abortion, Medical | Not applicable | Recruiting | Stony Brook University | 102 | 2025-02-10 | 2026-04-30 |
| Induction of Abortion in the Second Trimester hyoscine N-butyl bromide under the generic name of buscopan ampoule produced by Sanofi company, misoprostol under the generic name of misotac tablets - Abortion, Second Trimester | Early Phase 1 | Completed | Ain Shams Maternity Hospital | 40 | 2022-12-01 | 2024-01-17 |
| Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial Mifepristone, Misoprostol - Abortion, Second Trimester, PPROM | Phase 4 | Completed | Washington University School of Medicine | 30 | 2022-07-01 | 2026-04-07 |
| Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion Single Foley Balloon, Dilapan-S - Abortion, Second Trimester | Not applicable | Completed | Stanford University | 32 | 2022-02-08 | 2024-04-18 |
| Clotting Parameters After Medical Abortion Thromboelastometry, Clotting Studies, Full Blood Count - Abortion Early, Abortion, Complete | Completed | NHS Lothian | 45 | 2021-03-26 | 2022-04-20 | |
| Misoprostol With And Without Transcervical Balloon Catheter In Second Trimester Termination Of Pregnancy Misoprostol, Misoprostol/Transcervical catheter - Pregnancy Trimester, Second, Misoprostol | Phase 4 | Unknown | Ain Shams Maternity Hospital | 108 | 2017-03-01 | 2017-05-09 |
| 24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E Vaginal Misoprostol, Buccal Misoprostol - Abortion, Second Trimester | Phase 4 | Completed | Virginia Commonwealth University | 70 | 2016-11-19 | 2018-07-18 |
| Uterocervical Angle in the Termination of Second Trimester Pregnancy uterocervical angle - Abortion, Second Trimester | Completed | Kanuni Sultan Suleyman Training and Research Hospital | 120 | 2016-10-15 | 2017-09-06 | |
| Second-trimester TOP : a Retrospective Study Comparing Complications at 12-14 vs 14-16 Weeks of Gestation Abortion in First Trimester, Abortion, Second Trimester | Completed | Central Hospital, Nancy, France | 122 | 2010-01-01 | 2022-07-21 | |
| A Pilot Study of Priming Before Induction Termination of Pregnancy Addition of misoprostol 25 mcg 12 hours before induction - Abortion, Induced, Abortion, Second Trimester | Not applicable | Completed | Boston University | 25 | 2007-01-01 | 2008-10-07 |
| Mifepristone and Mid-Trimester Termination of Pregnancy Addition of mifepristone 200 mg 24 hours before induction - Abortion, Induced, Abortion, Second Trimester | Not applicable | Completed | Boston University | 64 | 2005-03-01 | 2008-10-07 |
Neoplasm Metastasis (2) · Dilatation, Pathologic (1) · Fetal Death (1) · Hemostatic Disorders (1) · Pain, Procedural (1) · Patient Satisfaction (1) · Pregnancy Complications (1) · Preterm Premature Rupture of the Membranes (1) · Rupture, Spontaneous (1) · Venous Thromboembolism (1) · Venous Thrombosis (1)
Pathological Conditions, Signs and Symptoms (5) · Pathologic Processes (3) · Neoplasms (2) · Neoplastic Processes (2) · Pathological Conditions, Anatomical (2) · Behavior (1) · Cardiovascular Diseases (1) · Death (1) · Embolism and Thrombosis (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Health Behavior (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Hemorrhagic Disorders (1) · Neurologic Manifestations (1)
Misoprostol (4) · Blood Cell Count (1) · Mifepristone (1) · Pregnancy Tests (1) · Thrombelastography (1)
Ain Shams Maternity Hospital (2) · Boston University (2) · Boston Medical Center (1) · Central Hospital, Nancy, France (1) · Kanuni Sultan Suleyman Training and Research Hospital (1) · NHS Lothian (1) · Stanford University (1) · Stony Brook University (1) · Virginia Commonwealth University (1) · Washington University School of Medicine (1)
United States (6) · Egypt (2) · Mozambique (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Alaa Elfeky, Professor (1) · Alev Atis, MD,ObGyn (1) · Anjanique Mariquit Lu, MD (1) · Frances Casey, MD (1) · John J Reynolds-Wright, MBChB (1) · Lynn Borgatta, MD, MPH (1) · Nilda L Moreno-Ruiz, MD (1) · Rania G Anwar El-Skaan (1)