3 completed, 2 terminated, 1 withdrawn. 4 Phase 1, 3 Phase 2.
By phase and status
Follow NantBioScience, Inc.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers. YE-NEO-001 - Colorectal Cancer, Breast Cancer | Phase 1 | Completed | NantBioScience, Inc. | 5 | 2018-08-10 | 2026-05-07 |
QUILT-3.014: A Trial of ABI-011 Administered Weekly in Patients With Advanced Solid Tumors or Lymphomas ABI-011 - Neoplastic Disease | Phase 1 | Withdrawn | NantBioScience, Inc. | | 2017-11-13 | 2019-08-28 |
QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer ETBX-021 - Cancer | Phase 1 | Terminated | NantBioScience, Inc. | 3 | 2017-03-04 | 2025-01-13 |
Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas Gemcitabine, AMG 479, Placebo - Adenocarcinoma of the Pancreas, Locally Advanced | Phase 2 | Terminated | NantBioScience, Inc. | 10 | 2012-05-31 | 2024-11-08 |
Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab Panitumumab, Ganitumab, Irinotecan - Metastatic Colorectal Cancer | Phase 2 | Completed | NantBioScience, Inc. | 74 | 2009-05-05 | 2024-07-17 |
Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC) Panitumumab, Ganitumab, Rilotumumab - Colon Cancer, Colorectal Cancer | Phase 1 / Phase 2 | Completed | NantBioScience, Inc. | 177 | 2008-10-27 | 2024-08-07 |
Conditions studied
Colorectal Neoplasms (3) · Breast Neoplasms (2) · Neoplasms (2) · Pancreatic Neoplasms (2) · Adenocarcinoma (1) · Breast Neoplasms, Male (1) · Carcinoma, Non-Small-Cell Lung (1) · Colonic Neoplasms (1) · Gastrointestinal Neoplasms (1) · Liver Neoplasms (1) · Lymphoma (1) · Melanoma (1) · Neoplasm Metastasis (1) · Rectal Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1)
Interventions
ganitumab (3) · Panitumumab (2) · Gemcitabine (1) · Injections (1) · Irinotecan (1) · Presenilin-1 (1) · Suspensions (1) · methyl N-acetylsibirosaminide (1) · rilotumumab (1)
Countries
United States (4) · Austria (1) · Belgium (1) · Czechia (1) · Denmark (1) · Germany (1) · Hungary (1) · Poland (1) · Portugal (1) · Russia (1) · South Korea (1) · Spain (1) · United Kingdom (1)
Top investigators
Mira Kistler, MD (1)
Results publications
PMID 26049686, PMID 28945848
NIH funding
2008 (1)