6 completed, 3 terminated. 5 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 4 | Terminated 3, Completed 1 |
Follow Complexa, Inc.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral CXA-10 in Pulmonary Arterial Hypertension CXA-10 - Pulmonary Arterial Hypertension | Phase 2 | Terminated | Gladwin, Mark, MD | 1 | 2019-10-31 | 2022-01-12 |
| CXA-10 Study in Subjects With Pulmonary Arterial Hypertension CXA-10 - PAH | Phase 2 | Terminated | Complexa, Inc. | 33 | 2019-08-09 | 2020-08-26 |
| PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH) 75mg CXA-10, 150mg CXA-10, Placebo - PAH | Phase 2 | Terminated | Complexa, Inc. | 69 | 2018-08-01 | 2020-08-10 |
| FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS) CXA-10 - Primary Focal Segmental Glomerulosclerosis | Phase 2 | Completed | Complexa, Inc. | 33 | 2018-04-15 | 2020-08-03 |
| A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males CXA-10, pravastatin, Vytorin® (combination of simvastatin and ezetimibe) - Acute Kidney Injury | Phase 1 | Completed | Complexa, Inc. | 10 | 2015-12-01 | 2016-05-03 |
| PK and PD of Sequential Multiple Ascending, Repeat Doses of Oral CXA-10 in Healthy Obese Male Subjects CXA-10, CXA-10 placebo - Acute Kidney Injury | Phase 1 | Completed | Complexa, Inc. | 43 | 2015-04-01 | 2016-05-03 |
| Oral CXA-10 Study in Healthy Volunteers CXA-10, CXA-10 placebo - Chronic Kidney Injury | Phase 1 | Completed | Complexa, Inc. | 40 | 2015-01-01 | 2016-05-03 |
| Open-Label Safety, Tolerability, PK Study of IV CXA-10 Emulsion in Subjects in Chronic Kidney Injury CXA-10 - Acute Kidney Injury (Nontraumatic) | Phase 1 | Completed | Complexa, Inc. | 12 | 2014-09-01 | 2018-02-01 |
| Study of CXA-10 in Healthy Volunteers CXA-10 emulsion, Placebo - Acute Kidney Injury (Nontraumatic) | Phase 1 | Completed | Complexa, Inc. | 30 | 2014-04-01 | 2018-02-01 |
Acute Kidney Injury (4) · Pulmonary Arterial Hypertension (3) · Cardiovascular Diseases (2) · Connective Tissue Diseases (2) · Familial Primary Pulmonary Hypertension (2) · Hypertension (2) · Hypertension, Pulmonary (2) · Lung Diseases (2) · Vascular Diseases (2) · Kidney Diseases (1) · Nephrotic Syndrome (1) · Proteinuria (1)
CXA-10 (8) · Ezetimibe (1) · Ezetimibe, Simvastatin Drug Combination (1) · Pravastatin (1)
United States (9) · United Kingdom (2)
Thomas Blok, MD (3) · Theo Danoff, MD (2) · James VanderLugt, MD (1) · Marc Simon, MD (1) · Theodore Danoff, MD (1)
P01HL103455 (1)