16 completed, 11 unknown, 2 terminated, 1 recruiting. 31 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 31 | Completed 16, Unknown 11, Terminated 2, Recruiting 1, Suspended 1 |
| Phase 1 | 3 | Recruiting 1, Suspended 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow TS-1: new trials by email Literature Review of TS-1 trials Research Report on TS-1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma hypofractionated radiotherapy, PD-1 inhibitor, TS-1 - Gastroesophageal Junction Adenocarcinoma, Hypofractionated Radiotherapy | Phase 1 / Phase 2 | Recruiting | West China Hospital | 84 | 2025-11-18 | 2026-01-06 |
| NGS as the First-line Treatment in Advanced Biliary Tract Cancer TS-1, Gemcitabine, Nivolumab - Advanced Biliary Tract Cancer | Phase 2 | Completed | National Health Research Institutes, Taiwan | 48 | 2019-12-27 | 2025-07-22 |
| Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With TS-1+Cisplatin or TS-1+Oxaliplatin as First Line Chemotherapy in Gastric Cancer (MK-3475-659/KEYNOTE-659) Pembrolizumab, Oxaliplatin, TS-1 - Gastric Cancer | Phase 2 | Completed | Merck Sharp & Dohme LLC | 100 | 2018-03-26 | 2024-06-11 |
| S-1, Irinotecan, and Oxaliplatin in Locally-Advanced Pancreatic Cancer Tegafur-gimeracil-oteracil potassium, Oxaliplatin, Irinotecan - Pancreatic Ductal Adenocarcinoma | Phase 2 | Unknown | National Taiwan University Hospital | 35 | 2017-11-01 | 2017-10-20 |
| Docetaxel and S-1 Combination Therapy as Second-line Treatment for Advanced Gastric Cancer Docetaxel, S-1 - Advanced Gastric Cancer | Phase 2 | Unknown | Fujian Cancer Hospital | 47 | 2017-06-01 | 2017-05-08 |
| A Randomized Phase II Trial of Neoadjuvant Chemotherapy Compared With Chemoradiotherapy in Gastric Adenocarcinoma SIB-IMRT, S-1, Surgery - Stomach Neoplasms, Neoadjuvant Therapy | Phase 2 | Completed | Chinese Academy of Medical Sciences | 71 | 2014-01-01 | 2019-10-16 |
| First Line Chemotherapy for Advanced Cancer albumin-bounded paclitaxel, S-1 - Gastric Cancer | Phase 2 | Terminated | Chinese Academy of Medical Sciences | 36 | 2013-09-01 | 2016-06-14 |
| SOX Versus XELOX for Patients With Peritoneal Metastasis of Colorectal Cancer SOX, XELOX - Colorectal Neoplasm | Phase 2 | Unknown | The First People's Hospital of Changzhou | 60 | 2013-01-01 | 2016-08-19 |
| Phase II Study of Gemcitabine Versus S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract Cancer Gemcitabine, S-1 - Biliary Tract Cancer | Phase 2 | Completed | Kansai Hepatobiliary Oncology Group | 70 | 2013-01-01 | 2018-05-16 |
| Cisplatin,Docetaxel and S-1 for Advanced Gastric and Gastroesophageal Junction Cancer Docetaxel, Cisplatin, S-1 - Gastric Cancer, Gastroesophageal Junction Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 40 | 2012-09-01 | 2012-12-12 |
| Study of TS-1 as 2nd Line Treatment in Patients With Advanced Metastatic Breast Cancer Tegafur Gimeracil Oteracil Potassium Capsule - Breast Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 30 | 2011-12-01 | 2013-03-15 |
| Docetaxel and S-1 for Advanced Esophageal Cancer DS (docetaxel+S-1) - Esophageal Neoplasms | Phase 2 | Unknown | Hallym University Medical Center | 37 | 2011-11-01 | 2017-08-23 |
| S-1/LV One Week on and One Week Off Regimen in Advanced Hepatocellular Carcinoma (HCC) S-1 combined with Leucovorin - Carcinoma, Liver Diseases | Phase 2 | Unknown | Second Military Medical University | 32 | 2011-11-01 | 2012-02-15 |
| S-1 Versus S-1 Plus Cisplatin as an Adjuvant Chemotherapy to Treat Gastric Cancer S-1, S-1 plus cisplatin - Gastric Cancer | Phase 2 | Unknown | Kyungpook National University Hospital | 218 | 2011-09-01 | 2012-01-05 |
| S-1, Gemcitabine and Erlotinib for Advanced Pancreatic Cancer GES (Gemcitabine, Erlotinib, S-1) - Pancreas Neoplasms | Phase 2 | Completed | Hallym University Medical Center | 37 | 2011-08-01 | 2017-08-23 |
| The Efficacy of Oxaliplatin Plus S-1 for Treatment of Gastric Cancer Oxaliplatin, s1 - Stomach Neoplasms | Phase 2 | Completed | Chinese Academy of Medical Sciences | 43 | 2011-06-01 | 2014-12-04 |
| SOX as Adjuvant Chemotherapy for Resectable Gastric Cancer s1, Oxaliplatin - Gastric Cancer | Phase 1 / Phase 2 | Unknown | Chinese Academy of Medical Sciences | 71 | 2011-06-01 | 2016-06-14 |
| A Phaseâ…¡ Study: SOX vs SP in Adjuvant Chemotherapy After D2 Surgery S-1, oxaliplatin, cisplatin - Gastric Cancer | Phase 2 | Unknown | Peking University | 160 | 2011-04-01 | 2015-05-19 |
| Neoadjuvant Combination Chemotherapy of DCS and DCF in Patients With Locally Advanced Gastric Adenocarcinoma DCS (docetaxel with cisplatin with TS-1), DCF (docetaxel with cisplatin with 5-FU) - Gastric Cancer | Phase 2 | Completed | Yonsei University | 6 | 2009-09-01 | 2024-12-27 |
| Postoperative Chemoradiotherapy With S-1 in Gastric Cancer S-1 - Gastric Cancer | Phase 2 | Completed | Chonnam National University Hospital | 46 | 2009-04-01 | 2013-04-04 |
Showing 20 of 31. Sign in to see all of them.
Stomach Neoplasms (13) · Pancreatic Neoplasms (4) · Colorectal Neoplasms (3) · Biliary Tract Neoplasms (2) · Breast Neoplasms (2) · Carcinoma (1) · Carcinoma, Hepatocellular (1) · Esophageal Neoplasms (1) · Head and Neck Neoplasms (1) · Liver Diseases (1) · Neoplasm Metastasis (1)
Chinese Academy of Medical Sciences (6) · Hallym University Medical Center (5) · Chonnam National University Hospital (2) · Hokkaido Gastrointestinal Cancer Study Group (2) · Japan Clinical Cancer Research Organization (2) · Andrew Ko (1) · Fujian Cancer Hospital (1) · Japan Breast Cancer Research Network (1) · Kansai Hepatobiliary Oncology Group (1) · Kyungpook National University Hospital (1) · Merck Sharp & Dohme LLC (1) · National Health Research Institutes, Taiwan (1) · National Taiwan University Hospital (1) · Osaka Medical Center for Cancer and Cardiovascular Diseases (1) · Peking University (1)
China (11) · South Korea (9) · Japan (8) · Taiwan (1) · United States (1)
Dae Young Zang, MD, PhD (4) · Lin Yang, MD (2) · Sang-Hee Cho, M.D.Ph.D. (2) · Aiping Zhou, M.D (1) · Andrew Ko, MD (1) · Atsushi Sofuni, M.D. PhD (1) · Binghe Xu, MD, PhD (1) · Changping Wu, M.D. (1) · Chen Ming-Huang, MD (1) · Chiang Nai-Jung, MD (1) · Dae Young Zang, DM, PhD (1) · Daigo Yamamoto, MD (1) · Hiroaki Nagano, MD, PhD (1) · Jinwan Wang, MD (1) · Masafumi Suyama, M.D. PhD (1)
PMID 23497365, PMID 26109630, PMID 29743043, PMID 32145474, PMID 35574368, PMID 40885799