26 completed, 12 unknown, 2 suspended, 2 terminated. 31 Phase 2, 9 Phase 3, 8 Phase 1.
Follow TS-1: new trials by email Literature Review of TS-1 trials Research Report on TS-1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma hypofractionated radiotherapy, PD-1 inhibitor, TS-1 - Gastroesophageal Junction Adenocarcinoma, Hypofractionated Radiotherapy | Phase 1 / Phase 2 | Recruiting | West China Hospital | 84 | 2025-11-18 | 2026-01-06 |
| NGS as the First-line Treatment in Advanced Biliary Tract Cancer TS-1, Gemcitabine, Nivolumab - Advanced Biliary Tract Cancer | Phase 2 | Completed | National Health Research Institutes, Taiwan | 48 | 2019-12-27 | 2025-07-22 |
| Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With TS-1+Cisplatin or TS-1+Oxaliplatin as First Line Chemotherapy in Gastric Cancer (MK-3475-659/KEYNOTE-659) Pembrolizumab, Oxaliplatin, TS-1 - Gastric Cancer | Phase 2 | Completed | Merck Sharp & Dohme LLC | 100 | 2018-03-26 | 2024-06-11 |
| S-1, Irinotecan, and Oxaliplatin in Locally-Advanced Pancreatic Cancer Tegafur-gimeracil-oteracil potassium, Oxaliplatin, Irinotecan - Pancreatic Ductal Adenocarcinoma | Phase 2 | Unknown | National Taiwan University Hospital | 35 | 2017-11-01 | 2017-10-20 |
| Phase I Study of TBI-1401(HF10) Plus Chemotherapy in Patients with Unresectable Pancreatic Cancer. TBI-1401(HF10), Gemcitabine, Nab-paclitaxel - Pancreatic Cancer Stage III, Pancreatic Cancer Stage IV | Phase 1 | Active not recruiting | Takara Bio Inc. | 36 | 2017-09-25 | 2024-12-09 |
| Docetaxel and S-1 Combination Therapy as Second-line Treatment for Advanced Gastric Cancer Docetaxel, S-1 - Advanced Gastric Cancer | Phase 2 | Unknown | Fujian Cancer Hospital | 47 | 2017-06-01 | 2017-05-08 |
| A Randomized Phase II Trial of Neoadjuvant Chemotherapy Compared With Chemoradiotherapy in Gastric Adenocarcinoma SIB-IMRT, S-1, Surgery - Stomach Neoplasms, Neoadjuvant Therapy | Phase 2 | Completed | Chinese Academy of Medical Sciences | 71 | 2014-01-01 | 2019-10-16 |
| First Line Chemotherapy for Advanced Cancer albumin-bounded paclitaxel, S-1 - Gastric Cancer | Phase 2 | Terminated | Chinese Academy of Medical Sciences | 36 | 2013-09-01 | 2016-06-14 |
| SOX Versus XELOX for Patients With Peritoneal Metastasis of Colorectal Cancer SOX, XELOX - Colorectal Neoplasm | Phase 2 | Unknown | The First People's Hospital of Changzhou | 60 | 2013-01-01 | 2016-08-19 |
| Phase II Study of Gemcitabine Versus S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract Cancer Gemcitabine, S-1 - Biliary Tract Cancer | Phase 2 | Completed | Kansai Hepatobiliary Oncology Group | 70 | 2013-01-01 | 2018-05-16 |
| S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for Advanced Gastric Cancer S-1, Cisplatin, Oxaliplatin - Gastric Cancer | Phase 3 | Completed | Min-Hee Ryu | 338 | 2012-12-01 | 2015-11-30 |
| Cisplatin,Docetaxel and S-1 for Advanced Gastric and Gastroesophageal Junction Cancer Docetaxel, Cisplatin, S-1 - Gastric Cancer, Gastroesophageal Junction Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 40 | 2012-09-01 | 2012-12-12 |
| S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal Cancer OIS (Oxaliplatin, Irinotecan, S-1) - Gastrointestinal Neoplasms | Phase 1 | Completed | Hallym University Medical Center | 22 | 2012-06-01 | 2016-02-19 |
| Study of TS-1 as 2nd Line Treatment in Patients With Advanced Metastatic Breast Cancer Tegafur Gimeracil Oteracil Potassium Capsule - Breast Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 30 | 2011-12-01 | 2013-03-15 |
| Docetaxel and S-1 for Advanced Esophageal Cancer DS (docetaxel+S-1) - Esophageal Neoplasms | Phase 2 | Unknown | Hallym University Medical Center | 37 | 2011-11-01 | 2017-08-23 |
| S-1/LV One Week on and One Week Off Regimen in Advanced Hepatocellular Carcinoma (HCC) S-1 combined with Leucovorin - Carcinoma, Liver Diseases | Phase 2 | Unknown | Second Military Medical University | 32 | 2011-11-01 | 2012-02-15 |
| S-1 Versus S-1 Plus Cisplatin as an Adjuvant Chemotherapy to Treat Gastric Cancer S-1, S-1 plus cisplatin - Gastric Cancer | Phase 2 | Unknown | Kyungpook National University Hospital | 218 | 2011-09-01 | 2012-01-05 |
| S-1, Gemcitabine and Erlotinib for Advanced Pancreatic Cancer GES (Gemcitabine, Erlotinib, S-1) - Pancreas Neoplasms | Phase 2 | Completed | Hallym University Medical Center | 37 | 2011-08-01 | 2017-08-23 |
| The Efficacy of Oxaliplatin Plus S-1 for Treatment of Gastric Cancer Oxaliplatin, s1 - Stomach Neoplasms | Phase 2 | Completed | Chinese Academy of Medical Sciences | 43 | 2011-06-01 | 2014-12-04 |
| SOX as Adjuvant Chemotherapy for Resectable Gastric Cancer s1, Oxaliplatin - Gastric Cancer | Phase 1 / Phase 2 | Unknown | Chinese Academy of Medical Sciences | 71 | 2011-06-01 | 2016-06-14 |
Showing 20 of 44. Sign in to see all of them.
Stomach Neoplasms (20) · Pancreatic Neoplasms (6) · Colorectal Neoplasms (4) · Biliary Tract Neoplasms (3) · Breast Neoplasms (2) · Carcinoma (1) · Carcinoma, Hepatocellular (1) · Esophageal Neoplasms (1) · Gastrointestinal Neoplasms (1) · Head and Neck Neoplasms (1) · Liver Diseases (1) · Neoplasm Metastasis (1)
Chinese Academy of Medical Sciences (6) · Hallym University Medical Center (6) · Hokkaido Gastrointestinal Cancer Study Group (3) · Japan Clinical Cancer Research Organization (3) · Chonnam National University Hospital (2) · Kansai Hepatobiliary Oncology Group (2) · National Health Research Institutes, Taiwan (2) · Taiho Pharmaceutical Co., Ltd. (2) · Andrew Ko (1) · AstraZeneca (1) · Fujian Cancer Hospital (1) · Hokuriku-Kinki Immunochemotherapy Study Group (1) · Japan Breast Cancer Research Network (1) · Kyungpook National University Hospital (1) · Merck Sharp & Dohme LLC (1)
Japan (18) · China (11) · South Korea (11) · Taiwan (3) · United States (1)
Dae Young Zang, MD, PhD (5) · Hiroaki Nagano, MD, PhD (2) · Lin Yang, MD (2) · Sang-Hee Cho, M.D.Ph.D. (2) · Aiping Zhou, M.D (1) · Andrew Ko, MD (1) · Atsushi Sofuni, M.D. PhD (1) · Binghe Xu, MD, PhD (1) · Changping Wu, M.D. (1) · Chen Ming-Huang, MD (1) · Chiang Nai-Jung, MD (1) · Dae Young Zang, DM, PhD (1) · Daigo Yamamoto, MD (1) · Ik-Joo Chung, MD., Ph.D. (1) · Jinwan Wang, MD (1)
PMID 38140879, PMID 16803844, PMID 18282805, PMID 18553228, PMID 23497365, PMID 23547081, PMID 24366758, PMID 26109630, PMID 28210843, PMID 29743043, PMID 32145474, PMID 32596783, PMID 35574368, PMID 40885799