7 completed, 1 suspended, 1 unknown. 9 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 7, Suspended 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow TS-1: new trials by email Literature Review of TS-1 trials Research Report on TS-1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for Advanced Gastric Cancer S-1, Cisplatin, Oxaliplatin - Gastric Cancer | Phase 3 | Completed | Min-Hee Ryu | 338 | 2012-12-01 | 2015-11-30 |
| Study of TS-1 or TS-1 + PSK for Gastric Cancer Patients Tegafur-gimeracil-oteracil potassium (TS-1), Krestin (PSK) - Gastric Cancer | Phase 3 | Unknown | Tokyo Metropolitan Oncology Group | 480 | 2008-06-01 | 2012-03-22 |
| Second Line Chemotherapy for S-1 Refractory Advanced Gastric Cancer S-1 + irinotecan, irinotecan - Gastric Cancer | Phase 2 / Phase 3 | Completed | Japan Clinical Cancer Research Organization | 300 | 2008-03-01 | 2011-06-28 |
| Phase III of Gemcitabine Vs TS-1 Vs Gemcitabine Plus TS-1 in Pancreatic Cancer Gemcitabine plus TS-1, TS-1, Gemcitabine - Pancreatic Cancer | Phase 3 | Completed | Taiho Pharmaceutical Co., Ltd. | 834 | 2007-07-01 | 2012-11-02 |
| IRIS Followed by mFOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer Campto, Topotesin, TS-1, L-Plat - Metastatic Colorectal Cancer | Phase 3 | Suspended | Hokkaido Gastrointestinal Cancer Study Group | 200 | 2006-04-01 | 2007-11-01 |
| Phase III Study of Docetaxel + S-1 vs. S-1 for Advanced Gastric Cancer docetaxel + S-1, S-1 - Gastric Cancer | Phase 3 | Completed | Japan Clinical Cancer Research Organization | 628 | 2006-03-01 | 2011-06-28 |
| Randomized Controlled Study of Postoperative Adjuvant Therapy for Gastric Cancer Using TS-1 or TS-1+PSK Tegafur-gimeracil-oteracil potassium (TS-1), Krestin (PSK) - Gastric Cancer | Phase 3 | Completed | Hokuriku-Kinki Immunochemotherapy Study Group | 255 | 2005-03-01 | 2016-06-07 |
| Study Evaluating Isovorin in Advanced/Recurrent Gastric Cancer Isovorin, TS-1 - Gastric Cancer | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 200 | 2002-05-01 | 2009-08-13 |
| Randomized Phase III Study of TS-1 Alone Versus TS-1 Plus CDDP in Advanced Gastric Cancer TS-1 and cisplatin, TS-1 - Gastric Cancer | Phase 3 | Completed | Taiho Pharmaceutical Co., Ltd. | 300 | 2002-03-01 | 2011-07-07 |
Stomach Neoplasms (7) · Colorectal Neoplasms (1) · Pancreatic Neoplasms (1)
Japan Clinical Cancer Research Organization (2) · Taiho Pharmaceutical Co., Ltd. (2) · Hokkaido Gastrointestinal Cancer Study Group (1) · Hokuriku-Kinki Immunochemotherapy Study Group (1) · Min-Hee Ryu (1) · Tokyo Metropolitan Oncology Group (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
Japan (8) · South Korea (1) · Taiwan (1)
Ik-Joo Chung, MD., Ph.D. (1) · Koichi Miwa, MD, PhD (1) · Masashi Fujii, M.D.,PhD (1) · Masashi Fujii, MD PhD (1) · Masatsugu Kitamura, MD (1) · Min-Hee Ryu, M.D., Ph.D (1) · Takuji Okusaka, MD (1) · Wasaburo Koizumi, MD, PHD (1) · Yoshito Komatsu, MD, PhD (1) · Young-Iee Park, MD., Ph.D. (1)
PMID 38140879, PMID 16803844, PMID 18282805, PMID 18553228, PMID 23547081, PMID 24366758, PMID 26109630, PMID 28210843, PMID 32596783