4 completed, 2 terminated, 2 unknown, 1 active not recruiting. 12 Phase 2, 3 Phase 1, 1 Phase 3.
Follow Trimethoprim: new trials by email Literature Review of Trimethoprim trials Research Report on Trimethoprim
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Folate Study in Men With Advanced Prostate Cancer Trimethoprim Tablets - Prostate Cancer | Phase 2 | Not yet recruiting | University of California, San Diego | 50 | 2026-06-01 | 2025-11-12 |
| Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting Gentamicin, Standard of Care - Urinary Tract Infections | Phase 2 | Unknown | Mercy Health Ohio | 160 | 2022-10-01 | 2023-01-27 |
| Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D ATSN-101, ATSN-101 Diluent Solution, Prednisone - Leber Congenital Amaurosis, LCA | Phase 1 / Phase 2 | Active not recruiting | Atsena Therapeutics Inc. | 15 | 2019-10-22 | 2026-08-03 |
| Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for Osteomyelitis Intravenous Antibacterial Agent, Oral Antibacterial Agent - Osteomyelitis | Phase 2 | Terminated | Loyola University | 30 | 2014-03-19 | 2018-07-19 |
| Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection VANCOMYCIN, CEFTRIAXONE, CLINDAMYCIN - Hip Prosthetic Joint Infection | Phase 2 | Unknown | University Hospital, Tours | 100 | 2012-10-01 | 2014-05-28 |
| Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP) Inhaled Vancomycin, Placebo (Sterile Water), Rifampin - Cystic Fibrosis | Phase 2 | Completed | Johns Hopkins University | 29 | 2012-10-01 | 2019-02-26 |
| Effects of Treatments on Atopic Dermatitis Trimethoprim/sulfamethoxazole (TMP/SMZ), Cephalexin, Doxycycline - Eczema, Dermatitis | Phase 2 | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 130 | 2012-09-18 | 2026-11-09 |
| The Efficacy of Trimethoprim in Wound Healing of Patients With Epidermolysis Bullosa Trimethoprim - Epidermolysis Bullosa | Phase 2 | Completed | The Hospital for Sick Children | 10 | 2006-09-01 | 2018-04-19 |
| Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV Isoniazid (INH), Trimethoprim/Sulfamethoxazole (TMP/SMX), Isoniazid Placebo (PL) - HIV Infection, Tuberculosis | Phase 2 / Phase 3 | Terminated | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | 1354 | 2004-02-01 | 2019-02-05 |
| Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults Alemtuzumab, Sirolimus, Tacrolimus - Kidney Transplantation, Kidney Disease | Phase 1 / Phase 2 | Completed | University of Wisconsin, Madison | 10 | 2003-11-01 | 2018-06-29 |
| Islet Transplantation for Type 1 Diabetes Islet Transplantation, Sirolimus, Tacrolimus - Diabetes Mellitus, Insulin-Dependent | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 36 | 2001-04-01 | 2017-03-15 |
| Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies Edetate Calcium Disodium, Ethanol, Trimethoprim-sulfamethoxazole - Chronic Myeloproliferative Disorders, Infection | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2013-02-15 |
Blast Crisis (1) · Burkitt Lymphoma (1) · Congenital Abnormalities (1) · Cystic Fibrosis (1) · Dermatitis (1) · Dermatitis, Atopic (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Eczema (1) · Epidermolysis Bullosa (1) · HIV Infections (1) · Hodgkin Disease (1) · Immunoblastic Lymphadenopathy (1) · Immunoglobulin Light-chain Amyloidosis (1) · Infections (1)
Atsena Therapeutics Inc. (1) · International Maternal Pediatric Adolescent AIDS Clinical Trials Group (1) · Johns Hopkins University (1) · Loyola University (1) · M.D. Anderson Cancer Center (1) · Mercy Health Ohio (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1) · The Hospital for Sick Children (1) · University Hospital, Tours (1) · University of California, San Diego (1) · University of Wisconsin, Madison (1)
United States (8) · Canada (2) · Italy (2) · Botswana (1) · France (1) · Germany (1) · South Africa (1) · Spain (1) · Switzerland (1)
A. D'jamali, MD, MS (1) · Charles D. Mitchell, MD (1) · Elena Pope, MD (1) · George McSherry, MD (1) · Heidi H Kong, M.D. (1) · James Chmiel, MD (1) · James Shapiro, MD, PhD (1) · Jorge Cortes, MD (1)
PMID 15257060, PMID 17005949, PMID 18230259, PMID 20607114, PMID 21732834, PMID 23438305, PMID 26872154, PMID 29654388, PMID 36511181
U01AI068632 (1)