6 unknown, 5 recruiting, 3 completed, 3 terminated. 18 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 18 | Unknown 6, Recruiting 5, Completed 3, Terminated 3, Not yet recruiting 1 |
| Phase 2 | 2 | Recruiting 1, Terminated 1 |
Follow TP protocol: new trials by email Literature Review of TP protocol trials Research Report on TP protocol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for Patients With PD-L1-Positive Locally Advanced or Metastatic NSCLC（SYNSTAR 04） SYS6010 injection, Enlonstobart injection, Tislelizumab injection - Non-Small Cell Lung Cancer | Phase 3 | Not yet recruiting | CSPC Megalith Biopharmaceutical Co.,Ltd. | 500 | 2026-06-02 | 2026-06-11 |
| CCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC PD-1 inhibitor, Unlimited radiotherapy, TP regimen - Esophageal Carcinoma, Radiotherapy | Phase 3 | Recruiting | Fudan University | 452 | 2025-02-01 | 2026-04-17 |
| Sintilimab and Chemotherapy Sequential Radiotherapy in Advanced Esophageal Cancer TP regimen (cis-platinum ; Tocetaxel ) combined with PD-1 inhibitors（Sintilimab） - Metastatic Esophageal Squamous Cell Carcinoma | Phase 2 / Phase 3 | Recruiting | Qingdao Central Hospital | 90 | 2023-09-20 | 2024-07-24 |
| Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer Neoadjuvant radiotherapy (arm A), Carboplatin, paclitaxel, Esophagectomy - Esophageal Squamous Cell Carcinoma | Phase 3 | Recruiting | Karolinska University Hospital | 1020 | 2020-11-27 | 2025-03-06 |
| Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy for Resectable Locally Advanced Esophageal Cancer (HCHTOG1903) Paclitaxel, Cisplatin, neoadjuvant chemoradiation therapy - Esophageal Squamous Cell Carcinoma | Phase 3 | Recruiting | Henan Cancer Hospital | 456 | 2019-10-22 | 2022-08-09 |
| A Trial Comparing Adjuvant Chemotherapy With Observation After Concurrent Chemoradiotherapy of Cervical Cancer (With Pelvic or Para-aortic Node Involvement) chemoradiation, Paclitaxel, Cisplatin - Cervical Cancer, Adjuvant Chemotherapy | Phase 3 | Unknown | Sun Yat-sen University | 432 | 2018-03-01 | 2018-03-26 |
| Addition of Cisplatin to Adjuvant Chemotherapy for Early Stage Breast Cancer in High-Risk Women Paclitaxel, Cisplatin, EC to docetaxel or paclitaxel - Tubular Breast Cancer, Mucinous Breast Cancer | Phase 3 | Recruiting | RenJi Hospital | 762 | 2017-07-27 | 2025-05-16 |
| Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer Adjuvant chemotherapy (Paclitaxel and Cisplatin), Adjuvant radiotherapy, Control group (Surgery alone) - Esophageal Neoplasms | Phase 3 | Unknown | Shanghai Chest Hospital | 486 | 2016-01-01 | 2016-09-07 |
| A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer Paclitaxel and Cisplatin, Paclitaxel and Fluorouracil, Paclitaxel and Carboplatin - Stage III Esophageal Squamous Cell Carcinoma | Phase 3 | Completed | Fudan University | 321 | 2015-07-01 | 2022-02-09 |
| Neoadjuvant Chemotherapy Versus Surgery Alone for Esophageal Squamous Cell Carcinoma cisplatin and paclitaxel - Esophageal Neoplasm | Phase 3 | Completed | Henan Cancer Hospital | 528 | 2015-06-01 | 2022-10-05 |
| Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Adjuvant Chemotherapy in the Treatment of the Lymph Node Positive Thoracic Esophageal Squamous Cell Carcinoma paclitaxel; cisplatin, radiation - Esophageal Cancer | Phase 3 | Unknown | Chinese Academy of Medical Sciences | 386 | 2015-04-01 | 2015-09-01 |
| Combination Treatment of S-1 With Paclitaxel in Advanced Esophageal Cancer S-1 and Paclitaxel, Paclitaxel and Cisplatin, 5-FU and Cisplatin - Esophageal Cancer | Phase 2 / Phase 3 | Terminated | Peking University | 4 | 2012-08-01 | 2017-04-07 |
| Concurrent Chemoradiotherapy With Weekly Cisplatin Versus Concurrent Chemoradiotherapy With Weekly Cisplatin and Paclitaxel in Locally Advanced Carcinoma Cervix Paclitaxel, Cisplatin, Cisplatin - Carcinoma Cervix | Phase 3 | Unknown | Indira Gandhi Medical College, Shimla | 80 | 2011-07-01 | 2012-05-08 |
| Adjuvant Platinum and Taxane in Triple-negative Breast Cancer (PATTERN) Paclitaxel Cisplatin, fluorouracil epirubicin cyclophosphamide and docetaxel (FEC-T) - Triple Negative Breast Cancer | Phase 3 | Completed | Fudan University | 647 | 2011-01-01 | 2020-05-19 |
| Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer Paclitaxel/Cisplatin, Reduced RT, 5-FU/Cisplatin - Head and Neck Cancer | Phase 3 | Terminated | University of Erlangen-Nürnberg Medical School | 221 | 2010-06-01 | 2021-05-04 |
| ERCC1 Targeted Trial Cisplatin, Paclitaxel - Lung Cancer | Phase 3 | Terminated | University College, London | 648 | 2009-10-01 | 2013-12-10 |
| Comparative Study of Individualized Sensitivity-Directed Chemotherapy Versus DTIC DTIC (dacarbazine), paclitaxel + cisplatin, treosulfan + cytarabine - Melanoma | Phase 3 | Unknown | University of Wuerzburg | 360 | 2008-10-01 | 2008-10-24 |
| Study on Paclitaxel Plus Topotecan in Comparison With Topotecan Plus Cisplatin in Recurrent or Persistent Cervical Carcinoma Paclitaxel, Cisplatin/Paclitaxel - Recurrent, Persistent or Metastasized Cervical Cancer | Phase 3 | Unknown | Institut fuer Frauengesundheit | 312 | 2006-09-01 | 2012-04-12 |
Esophageal Neoplasms (5) · Esophageal Squamous Cell Carcinoma (4) · Carcinoma, Non-Small-Cell Lung (2) · Lymphatic Metastasis (2) · Uterine Cervical Neoplasms (2) · Carcinoma, Ductal, Breast (1) · Carcinoma, Squamous Cell (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Melanoma (1) · Neoplasm Metastasis (1) · Recurrence (1) · Triple Negative Breast Neoplasms (1)
Fudan University (3) · Henan Cancer Hospital (2) · CSPC Megalith Biopharmaceutical Co.,Ltd. (1) · Chinese Academy of Medical Sciences (1) · Indira Gandhi Medical College, Shimla (1) · Institut fuer Frauengesundheit (1) · Karolinska University Hospital (1) · Peking University (1) · Qingdao Central Hospital (1) · RenJi Hospital (1) · Shanghai Chest Hospital (1) · Sun Yat-sen University (1) · University College, London (1) · University of Erlangen-Nürnberg Medical School (1) · University of Wuerzburg (1)
China (10) · Germany (3) · Canada (1) · India (1) · Ireland (1) · Norway (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Falk Thiel, Dr. med. (1) · Florian Lordick, MD, PhD (1) · Jinsong Lu, M.D. (1) · Kuaile Zhao, MD (1) · Magnus Nilsson, MD, PhD (1) · Pragyat Thakur, MBBS (1) · Rainer Fietkau, MD (1) · Selma Ugurel, Prof. (MD) (1) · Siow M. Lee, MD, PhD, FRCP (1) · Wei-jun Ye, M.D (1) · Wentao Fang, MD (1) · Xiaodong Zhang, MD (1) · Yin Li, MD.&PhD. (1)
PMID 14673047, PMID 20421764, PMID 20626450, PMID 25164541, PMID 26530541, PMID 26904570, PMID 30344165, PMID 32044419, PMID 32293362, PMID 32789480, PMID 35188552, PMID 35912196, PMID 38490057
2005 (1)