11 completed, 3 unknown, 2 recruiting, 1 terminated. 8 Phase 3, 5 Not applicable, 1 Early Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 7, Recruiting 1 |
| Not applicable | 5 | Unknown 2, Completed 1, Recruiting 1, Terminated 1 |
| Early Phase 1 | 1 | Unknown 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Topical corticosteroid: new trials by email Literature Review of Topical corticosteroid trials Research Report on Topical corticosteroid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus. Photobiomodulation using 635 nm diode laser, Photodynamic therapy - laser mucosal treatment, Clobetasol propionate 0.05 percent topical application - Oral Lichen Planus, Erosive Lichen Planus | Not applicable | Recruiting | Medical University of Silesia | 60 | 2025-12-01 | 2026-04-30 |
| Evaluation of 611 in Combination With Topical Corticosteroid in Participants With Moderate to Severe Atopic Dermatitis 611, Placebo, Topical corticosteroid - Dermatitis, Atopic, Eczema, Atopic | Phase 3 | Completed | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 417 | 2024-09-23 | 2026-09-17 |
| Parasitic Ulcer Treatment Trial Polyhexamethylene biguanide (PHMB), Topical corticosteroid, Topical placebo - Acanthamoeba Keratitis | Phase 3 | Recruiting | Jeremy Keenan, MD, MPH | 232 | 2024-07-01 | 2026-10-01 |
| A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis Placebo, Lebrikizumab, Topical Corticosteroid - Atopic Dermatitis | Phase 3 | Completed | Eli Lilly and Company | 301 | 2024-04-24 | 2026-10-16 |
| Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level in Patients With Erosive Oral Lichen Planus Topical corticosteroid and Vitamin E, Topical corticosteroid - Lichen Planus | Not applicable | Completed | Hams Hamed Abdelrahman | 52 | 2022-10-20 | 2023-03-28 |
| Role of Tofacitinib in Vitiligo Patients JAK-2 inhibitor, Topical corticosteroid - Vitiligo, Effect of Drug | Early Phase 1 | Unknown | Pi Research Consultancy Center, Bangladesh | 80 | 2022-05-30 | 2022-03-24 |
| A Study of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroids in Japanese Participants With Moderate-to-Severe Atopic Dermatitis Lebrikizumab, Placebo, Topical Corticosteroid - Dermatitis, Atopic, Dermatitis | Phase 3 | Completed | Eli Lilly and Company | 286 | 2021-03-10 | 2023-08-23 |
| Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis. Lebrikizumab, Placebo, Topical Corticosteroid - Atopic Dermatitis | Phase 3 | Completed | Eli Lilly and Company | 228 | 2020-02-03 | 2022-05-09 |
| Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease Diode laser 980nm&100 mWatt, Triamcinolone Acetonide - Autoimmune, Behcet Syndrome | Not applicable | Unknown | Cairo University | 38 | 2019-05-25 | 2019-04-09 |
| A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis Baricitinib, Placebo, Topical corticosteroid - Atopic Dermatitis | Phase 3 | Completed | Eli Lilly and Company | 516 | 2019-05-24 | 2026-08-05 |
| Evaluation of Salivary Level of miR-155 and IL-10 in Oral Lichen Planus Patients Before and After Treatment With Topical Corticosteroid Triamcinolone Acetonide in orabase - Oral Lichen Planus | Completed | Cairo University | 30 | 2019-03-10 | 2019-07-26 | |
| Fractional Carbon Dioxide Laser,Topical Corticosteroid and Narrow Band Ultraviolet B in Treatment of Stable Vitiligo fractional carbon dioxide(CO2) laser, Topical corticosteroid, Ultraviolet B narrow band - Vitiligo | Not applicable | Unknown | Assiut University | 25 | 2018-12-01 | 2018-11-28 |
| A Study of Baricitinib (LY3009104) in Combination With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis Baricitinib, Topical corticosteroid, Placebo - Atopic Dermatitis | Phase 3 | Completed | Eli Lilly and Company | 329 | 2018-11-16 | 2020-08-11 |
| Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone 532nm laser, 1064nm laser, Topical corticosteroid - Cutaneous Lupus | Not applicable | Terminated | David Weinstein | 3 | 2018-08-17 | 2021-07-21 |
| A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically Advisable Baricitinib, Placebo, Topical corticosteroid - Atopic Dermatitis | Phase 3 | Completed | Eli Lilly and Company | 463 | 2018-05-15 | 2024-05-14 |
| Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planus Bifidobacterium animalis subsp. lactis HN019, Clobetasol propionate 0.05% - Oral Lichen Planus | Phase 2 | Completed | University of Sao Paulo | 22 | 2017-11-06 | 2020-03-27 |
| Steroids for Corneal Ulcers Trial Antibiotics, Topical corticosteroid, Placebo - Corneal Ulcer, Eye Infections, Bacterial | Phase 4 | Completed | Thomas M. Lietman | 500 | 2006-09-01 | 2018-08-01 |
Dermatitis, Atopic (7) · Eczema (5) · Lichen Planus, Oral (3) · Corneal Ulcer (2) · Dermatitis (2) · Lichen Planus (2) · Skin Diseases (2) · Vitiligo (2) · Acanthamoeba Keratitis (1) · Bacterial Infections (1) · Behcet Syndrome (1) · Eye Diseases (1) · Eye Infections, Bacterial (1) · Oral Ulcer (1) · Skin Diseases, Genetic (1)
Eli Lilly and Company (6) · Cairo University (2) · Assiut University (1) · David Weinstein (1) · Hams Hamed Abdelrahman (1) · Jeremy Keenan, MD, MPH (1) · Medical University of Silesia (1) · Pi Research Consultancy Center, Bangladesh (1) · Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. (1) · Thomas M. Lietman (1) · University of Sao Paulo (1)
Poland (5) · Brazil (4) · Germany (4) · Japan (4) · United States (4) · Austria (3) · India (3) · Spain (3) · United Kingdom (3) · Argentina (2) · Australia (2) · China (2) · Egypt (2) · France (2) · Italy (2)
Dariusz Skaba (1) · Ellen E Monteiro, Student (1) · Gerami Seitzman, MD (1) · Gilberto A Silva, MS (1) · Jakub Fiegler-Rudol (1) · Jeremy Keenan, MD, MPH (1) · Kleber Tanaka Suzuki, DDS (1) · Lara Maria A Innocentini, DDS,PhD (1) · M. Srinivasan, M.S., O.D. (1) · Michel Reis Messora, DDS, PhD (1) · Mike Zegans, M.D. (1) · Mohammad Jahid Hasan, MPH (1)
PMID 33826132, PMID 36255569, PMID 18829631, PMID 21987582, PMID 22159005, PMID 22395880, PMID 22447793, PMID 22959881, PMID 23307105, PMID 23385795, PMID 24315294, PMID 24612976, PMID 24618327, PMID 27631025, PMID 33001140, PMID 33899152, PMID 34212234, PMID 34275122, PMID 36630140, PMID 36749121, PMID 39442013, PMID 39522957
2018 (2), 2017 (1), 2019 (1), U10EY015114 (1), UG1EY033284 (1)