8 completed, 4 unknown, 2 terminated, 1 not yet recruiting. 16 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 8, Unknown 4, Terminated 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Completed 2 |
Follow Tinzaparin: new trials by email Literature Review of Tinzaparin trials Research Report on Tinzaparin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity Aspirin, Low-molecular-weight heparin - Venous Thromboembolism, Postpartum Period | Phase 3 | Recruiting | University of Calgary | 8805 | 2026-06-04 | 2026-07-27 |
| Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention rivaroxaban and ASA, Low-molecular weight heparin, Fondaparinux - Hip Fracture Surgery, Cardiovascular Prevention | Phase 3 | Not yet recruiting | McMaster University | 100 | 2025-12-01 | 2025-11-14 |
| TINzaparin Prophylaxis in Patients With Metastatic Colorectal Cancer Tinzaparin - Colorectal Cancer Metastatic, Thromboembolism | Phase 3 | Completed | Galician Research Group on Digestive Tumors | 232 | 2023-03-02 | 2025-08-22 |
| The Impact of Thromboprophylaxis on Progression Free Survival of Patients With Advanced Pancreatic Cancer Innohep, Chemotherapy: Gemcitabine + Nab-Paclitaxel - Pancreatic Cancer, Thromboembolism | Phase 3 | Unknown | Michalis Karamouzis | 450 | 2022-02-10 | 2022-03-29 |
| Australasian COVID-19 Trial (ASCOT) ADAptive Platform Trial (Arm Closed) Nafamostat Mesilate, (Arm Closed) Enoxaparin, (Arm Closed) Dalteparin - SARS-CoV-2 Infection (COVID-19) | Phase 3 | Unknown | University of Melbourne | 2200 | 2020-07-28 | 2024-05-16 |
| Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer (PROVE) Tinzaparin Sodium - Venous Thromboembolism, Lung Neoplasm | Phase 3 | Terminated | Assistance Publique - Hôpitaux de Paris | 59 | 2018-09-14 | 2022-11-17 |
| A Study of Dabigatran Etexilate as Primary Treatment of Malignancy Associated Venous Thromboembolism Dabigatran etexilate, Tinzaparin - Venous Thromboembolism, Deep Vein Thrombosis | Phase 3 | Unknown | The University of Hong Kong | 99 | 2017-09-01 | 2019-04-17 |
| Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment Sildenafil, low molecular weight heparin - Fetal Growth Abnormality, Fetal Growth Restriction | Phase 3 | Unknown | Ain Shams University | 100 | 2017-06-01 | 2017-07-26 |
| Therapeutic Anticoagulation Strategy for Acute Chest Syndrome Prophylactic anticoagulation ( INNOHEP®), Curative anticoagulation ( INNOHEP®) - Anemia, Sickle Cell | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 198 | 2016-12-16 | 2024-02-09 |
| Extended Peri-operative Tinzaparin to Improve Disease-free Survival in Patients With Resectable Colorectal Cancer Tinzaparin - Adenocarcinoma of the Colon | Phase 3 | Completed | Ottawa Hospital Research Institute | 616 | 2011-09-01 | 2021-05-17 |
| Long-Term Innohep® Treatment Versus a Vitamin K Antagonist (Warfarin) for the Treatment of Venous Thromboembolism (VTE) in Cancer Warfarin, Innohep® - Venous Thromboembolism | Phase 3 | Completed | LEO Pharma | 900 | 2010-08-01 | 2025-02-24 |
| Long-term Treatment for Cancer Patients With Deep Venous Thrombosis or Pulmonary Embolism low molecular weight heparin, vitamin K antagonists - Venous Thromboembolism, Neoplasms | Phase 3 | Terminated | University Medical Center Groningen | 56 | 2010-08-01 | 2014-12-03 |
| Effect of Low Molecular Weight Heparin: Tinzaparin in Lung Tumours (TILT) Tinzaparin sodium 100 UI/Kg/OD for 12 weeks - Lung Cancer, Non Small Cell Lung Cancer | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 553 | 2007-06-01 | 2016-09-02 |
| A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery Fragmin (dalteparin), Innohep (tinzaparin) - Thromboembolism, Hemodialysis | Phase 2 / Phase 3 | Completed | Ottawa Hospital Research Institute | 29 | 2003-10-01 | 2014-09-10 |
| The STOP CLOT Pilot Study: Study of Low Molecular Weight Heparin in High Risk Cesarean Section Tinzaparin - Deep Vein Thrombosis | Phase 2 / Phase 3 | Completed | Ottawa Hospital Research Institute | 30 | 2002-07-01 | 2018-02-07 |
| Evaluation of Long-Term Sequelae After Thrombophlebitis, i.e. Deep Venous Thrombosis of the Lower Extremities unfractionated heparin, Tinzaparin (Leo) - Deep Venous Thrombosis | Phase 3 | Completed | Aalborg University Hospital | 99 | 1993-10-01 | 2008-03-05 |
Venous Thromboembolism (6) · Venous Thrombosis (5) · Thromboembolism (3) · Lung Neoplasms (2) · Pulmonary Embolism (2) · Acute Chest Syndrome (1) · Anemia (1) · Anemia, Sickle Cell (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Fetal Growth Retardation (1) · Hemorrhage (1) · Kidney Failure, Chronic (1)
Assistance Publique - Hôpitaux de Paris (3) · Ottawa Hospital Research Institute (3) · Aalborg University Hospital (1) · Ain Shams University (1) · Galician Research Group on Digestive Tumors (1) · LEO Pharma (1) · McMaster University (1) · Michalis Karamouzis (1) · The University of Hong Kong (1) · University Medical Center Groningen (1) · University of Calgary (1) · University of Melbourne (1)
Canada (7) · France (5) · Belgium (2) · Denmark (2) · Italy (2) · Netherlands (2) · Australia (1) · Egypt (1) · Germany (1) · Greece (1) · Hong Kong (1) · Ireland (1) · Poland (1) · Spain (1) · United States (1)
Guy Meyer, MD (2) · Marc Rodger, MD (2) · Agnes Y. Y. Lee, MD, MSc, FRCPC (1) · Armand Mekontso Dessap, MD, PhD (1) · Benedicte Laursen, MD, DMSc (1) · Bernard Maitre, MD, PhD (1) · Federico Germini, Doctor of Medicine (1) · Gloria Hwang, MBBS (1) · Harry R. Buller, MD, PhD (1) · Leslie Skeith, MD (1) · Marc Carrier, MD (1) · Marc Rodger, MD, MSc (1) · Mercedes Salgado, M.D. Ph.D. (1) · Pieter W. Kamphuisen, MD, PhD (1)
PMID 15302749, PMID 16458642, PMID 23764005, PMID 26284719, PMID 29618162, PMID 30262574, PMID 33337539, PMID 33779986, PMID 34878173, PMID 34953516, PMID 36100263, PMID 36514143, PMID 38189593, PMID 38320033, PMID 38320527, PMID 40209087, PMID 41249955
2009 (1), 2016 (1)