6 unknown, 5 completed, 1 not yet recruiting, 1 terminated. 14 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Unknown 6, Completed 5, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 4 | Unknown 3, Terminated 1 |
Follow Thrombopoietin: new trials by email Literature Review of Thrombopoietin trials Research Report on Thrombopoietin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multicenter Randomized Controlled Study on the Treatment of Refractory CTIT With Romiplostim N01 Compared to Recombinant Human Thrombopoietin Romiplostim N01, Recombinant Human Thrombopoietin - CTIT-Chemotherapy Induced Thrombocytopenia | Phase 3 | Unknown | Shandong University | 60 | 2024-06-01 | 2024-06-04 |
| Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT decitabine, umbilical cord blood, Granulocyte-colony stimulating factor - Poor Graft Function | Phase 3 | Not yet recruiting | The First Affiliated Hospital of Soochow University | 100 | 2023-08-01 | 2023-06-09 |
| A Randomized Trial of rhTPO Versus Placebo for Low/Intermediate-1 Risk MDS With Thrombocytopenia Danazol + rhTPO (recombinant human thrombopoietin injection), Danazol + sodium chloride - Low/Intermediate Risk-1 MDS | Phase 2 / Phase 3 | Unknown | Peking Union Medical College Hospital | 75 | 2020-03-01 | 2020-03-27 |
| The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia rhTPO, Placebo - Sepsis, Thrombocytopenia | Phase 2 / Phase 3 | Unknown | Ruilan Wang | 200 | 2019-04-01 | 2024-04-18 |
| Recombinant Human Thrombopoietin(rhTPO) in Pregnancy With Immune Thrombocytopenia recombinant human thrombopoietin, Platelet Concentrate - Immune Thrombocytopenia | Phase 3 | Unknown | Shandong University | 90 | 2018-05-01 | 2018-04-10 |
| Prospective Study of Patients With Thrombocytopenia Following HSCT Decitabine, rhTPO, Conventional Treatment - Thrombocytopenia, Hematologic Diseases | Phase 3 | Completed | The First Affiliated Hospital of Soochow University | 97 | 2015-10-01 | 2020-05-06 |
| Megakaryocytic Progenitor Cells for Prophylaxis and Treatment of Thrombocytopenia MPs, thrombopoietin (TPO) and interleukin-11 - Hematological Diseases, Thrombocytopenia | Phase 2 / Phase 3 | Unknown | Nanfang Hospital, Southern Medical University | 250 | 2014-09-01 | 2014-09-16 |
| An Investigation of rhTPO With Different Frequencies in the Management of ITP Recombinant Human Thrombopoietin (rhTPO) - Immune Thrombocytopenia | Phase 3 | Completed | Shandong University | 48 | 2014-05-01 | 2016-04-20 |
| Recombinant Human Thrombopoietin (rhTPO) Combining Rituximab Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) recombinant human thrombopoietin (rhTPO); rituximab, Dexamethasone - Purpura, Idiopathic Thrombocytopenic Purpura | Phase 3 | Withdrawn | Shandong University | 2012-07-01 | 2016-04-20 | |
| rhTPO Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of ITP recombinant human thrombopoietin (rhTPO); dexamethasone, Dexamethasone - Purpura, Idiopathic Thrombocytopenic Purpura | Phase 3 | Completed | Shandong University | 158 | 2012-07-01 | 2016-04-20 |
| rhTPO Combining Rituximab Versus Low-dose Rituximab in Management of ITP rituximab; recombinant human thrombopoietin (rhTPO), Rituximab - Purpura, Idiopathic Thrombocytopenic Purpura | Phase 3 | Completed | Shandong University | 123 | 2011-05-01 | 2016-04-20 |
| Clinical Trial on the Prevention of Thrombocytopenia After First-line Chemotherapy recombinant human thrombopoietin - Carcinoma, Non-Small-Cell Lung | Phase 2 / Phase 3 | Terminated | Chinese Society of Lung Cancer | 11 | 2011-02-01 | 2017-03-03 |
| Efficacy and Safety Study of Maintenance Treatment With rhTPO in Thrombocytopenic Subjects With ITP rhTPO - Thrombocytopenia, Immune Thrombocytopenia | Phase 3 | Unknown | Peking Union Medical College | 120 | 2011-02-01 | 2013-03-06 |
| Recombinant Human Thrombopoietin in Combination With Rituximab in Immune Thrombocytopenia (ITP) rhTPO in combination with Rituximab - Purpura, Idiopathic Thrombocytopenic Purpura | Phase 3 | Completed | Ming Hou | 91 | 2009-06-01 | 2016-04-20 |
Purpura, Thrombocytopenic, Idiopathic (7) · Purpura (4) · Thrombocytopenia (4) · Hematologic Diseases (2) · Carcinoma, Non-Small-Cell Lung (1) · Sepsis (1)
Shandong University (6) · The First Affiliated Hospital of Soochow University (2) · Chinese Society of Lung Cancer (1) · Ming Hou (1) · Nanfang Hospital, Southern Medical University (1) · Peking Union Medical College (1) · Peking Union Medical College Hospital (1) · Ruilan Wang (1)
China (12)
Ming Hou, Dr. (2) · Depei Wu, PhD,MD (1) · Hou Ming, Dr. (1) · Minf Hou, Dr. (1) · Ming Hou, Dr (1) · Ming Hou,, Dr (1) · Qifa Liu, MD (1) · Ruilan Wang, MD,PhD (1) · Yi-Long Wu, Professor (1) · Yongqiang Zhao, Dr. (1) · Yue Han (1)
PMID 12944568, PMID 17077333, PMID 19005182, PMID 19846889, PMID 33646303, PMID 16818281, PMID 18510702, PMID 21713321, PMID 25566808, PMID 25575541, PMID 26181032, PMID 27088376, PMID 31492102, PMID 32871029, PMID 34492685, PMID 34778037, PMID 3881142