4 completed, 1 terminated, 1 withdrawn. 6 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Terminated 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow Thiamine: new trials by email Literature Review of Thiamine trials Research Report on Thiamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HAT for the Treatment of Sepsis Associated With NASTI HAT, Placebo - Necrotizing Soft Tissue Infection, Sepsis | Phase 1 / Phase 2 | Terminated | Ascension Health | 10 | 2021-09-10 | 2024-07-24 |
| Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial Thiamine, Placebo - Heart Failure, Heart Failure With Reduced Ejection Fraction | Phase 1 | Completed | Hamilton Health Sciences Corporation | 24 | 2018-04-02 | 2021-08-31 |
| Thiamine Supplementation in Patients With Septic Shock Thiamine, Placebos - Septic Shock, Shock, Septic | Phase 1 | Withdrawn | The Cleveland Clinic | 2016-11-05 | 2019-03-15 | |
| Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) Progressive exercise, Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV, Modified paleolithic diet - Multiple Sclerosis | Phase 1 | Completed | University of Iowa | 38 | 2010-10-01 | 2018-06-26 |
| Thiamine as a Metabolic Resuscitator in Septic Shock D5W, Thiamine - Septic Shock | Phase 1 / Phase 2 | Completed | Beth Israel Deaconess Medical Center | 88 | 2010-02-01 | 2017-05-15 |
| Pharmacokinetics of Oral Thiamine Thiamine, Placebo - Pharmacokinetics in Healthy Subjects | Phase 1 | Completed | Baystate Medical Center | 14 | 2009-06-01 | 2011-09-14 |
Sepsis (2) · Shock, Septic (2) · Thiamine Deficiency (2) · Acidosis, Lactic (1) · Heart Failure (1) · Multiple Sclerosis (1) · Multiple Sclerosis, Chronic Progressive (1)
Ascension Health (1) · Baystate Medical Center (1) · Beth Israel Deaconess Medical Center (1) · Hamilton Health Sciences Corporation (1) · The Cleveland Clinic (1) · University of Iowa (1)
United States (5) · Canada (1)
Eric KC Wong, MD FRCPC (1) · Howard Smithline, MD (1) · Jinesh Mehta, MD (1) · Michael W Donnino, MD (1) · Thomas Resch, M.D. (1)