11 completed, 2 withdrawn. 13 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 11, Withdrawn 2 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 1 | Completed 1 |
Follow Testosterone gel: new trials by email Literature Review of Testosterone gel trials Research Report on Testosterone gel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ITT-5 Mechanisms of Spermatogenesis in Man Testosterone 1% Gel, Acyline, Dutasteride - Gonadotropin Deficiency | Phase 2 | Withdrawn | University of Washington | 2019-06-01 | 2019-12-18 | |
| A One Year Open Label Study for the Treatment of Hypogonadism (Low Testosterone) in Men Who Have Completed ZA-203 Androxal (enclomiphene citrate), Testim (topical testosterone) - Hypogonadism, Low Testosterone | Phase 2 | Completed | Repros Therapeutics Inc. | 48 | 2011-07-01 | 2013-05-17 |
| The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone) Androxal (enclomiphene citrate), Testosterone - Secondary Hypogonadism | Phase 2 | Completed | Repros Therapeutics Inc. | 60 | 2011-06-01 | 2015-09-23 |
| ITT4 Intratesticular Hormonal Milieu in Man (ITT4) Acyline, Testosterone gel, ketoconazole 400 - Healthy Males | Phase 1 / Phase 2 | Completed | University of Washington | 46 | 2011-01-01 | 2014-03-31 |
| HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone Acyline, placebo hCG (no active ingredient), hCG (human chorionic gonadotropin) - Healthy Males | Phase 1 / Phase 2 | Completed | University of Washington | 59 | 2009-03-01 | 2016-01-11 |
| PROS-1-Male Hormonal Contraceptive Regimens on Prostate Tissue Testosterone gel, Dutasteride, Depo-Medroxyprogesterone (DMPA) - Healthy | Phase 2 / Phase 3 | Completed | University of Washington | 32 | 2009-01-01 | 2013-11-15 |
| CEP-1 Hormonal Regulation of Circulating Endothelial Progenitor Cells and HDL-C in Men Acyline, Acyline + Testosterone gel, Acyline + testosterone gel + anastrozole - Healthy | Phase 2 | Completed | University of Washington | 31 | 2008-12-01 | 2012-10-12 |
| Analgesic Efficacy of Testosterone Replacement in Hypogonadal Opioid-treated Chronic Pain Patients: A Pilot Study. Testosterone Gel - Pain, Hypogonadism | Phase 2 | Withdrawn | James J. Peters Veterans Affairs Medical Center | 2006-10-30 | 2023-10-13 | |
| Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception AndroGel, Placebo - Pain, Hypogonadism | Phase 2 | Completed | Boston University | 84 | 2006-04-01 | 2017-06-28 |
| Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum Acyline, Testosterone Gel, Depo-Medroxyprogesterone - Contraception | Phase 1 / Phase 2 | Completed | University of Washington | 23 | 2004-12-01 | 2008-09-19 |
| Testosterone Therapy After Hip Fracture in Elderly Women Testosterone gel - Hip Fracture, Testosterone Deficiency | Phase 2 | Completed | Washington University School of Medicine | 15 | 2004-08-01 | 2009-02-04 |
| Male Hormonal Contraceptive Development-ACY-5 Acyline, Testosterone Gel, Depo-Medroxyprogesterone - Contraception | Phase 1 / Phase 2 | Completed | University of Washington | 43 | 2004-05-01 | 2008-09-19 |
| Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer GnRh (Leuprolide), Testosterone Gel, Docetaxel - Prostate Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 102 | 2003-07-01 | 2023-11-07 |
Hypogonadism (5) · Pain (2) · Depression (1) · Fatigue (1) · Hip Fractures (1) · Insulin Resistance (1) · Muscle Weakness (1) · Neoplasms (1) · Prostatic Neoplasms (1)
University of Washington (7) · Repros Therapeutics Inc. (2) · Boston University (1) · James J. Peters Veterans Affairs Medical Center (1) · Memorial Sloan Kettering Cancer Center (1) · Washington University School of Medicine (1)
United States (11)
William J Bremner, MD, PhD (2) · Christopher P Cardozo, M.D. (1) · Dana Rathkopf, MD, PhD (1) · Ellen F. Binder, MD (1) · Jolene Berg, MD (1) · Mara Roth, MD (1) · Mara Y Roth, MD (1) · Shehzad Basaria, MD (1) · Stephanie Page, MD, PhD (1) · Stephanie T Page, MD, PhD (1) · William Bremner, MD (1) · William Bremner, MD, PhD (1)
PMID 17494097, PMID 16940442, PMID 17303493, PMID 20484472, PMID 21797916, PMID 22266332, PMID 23040523, PMID 23348398, PMID 25599449, PMID 27992261, PMID 28981994
U54HD042454 (3), U54HD012629 (2)