21 completed, 7 recruiting, 6 unknown, 3 not yet recruiting. 24 Not applicable, 11 Phase 2, 6 Phase 1, 3 Phase 4, 2 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Taurine Supplementation in Adolescents With Post-COVID Condition Taurine - Long COVID, Post COVID-19 Condition | Phase 1 / Phase 2 | Not yet recruiting | University of Alberta | 30 | 2026-12-30 | 2026-10-16 |
| TCP-600 Supplementation and Performance Response in Professional Football Players Placebo, Taurine, Caffeine - Athletic Performance, Cognitive Fatigue | Not applicable | Completed | Vizja University in Warsaw | 65 | 2026-09-07 | 2026-11-04 |
| Phosphatidylserine, Taurine, and Caffeine for Cognitive Fatigue in Professional Football Players Placebo, Taurine Plus Caffeine, Taurine, Caffeine, and Phosphatidylserine - Mental Fatigue, Cognitive Performance | Not applicable | Completed | Vizja University in Warsaw | 65 | 2026-08-06 | 2026-09-14 |
| Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients Butyrate and Taurine, Placebo - Pain, Acute, Pain, Chronic | Not applicable | Recruiting | Chinese University of Hong Kong | 216 | 2026-06-20 | 2026-10-22 |
| Multi-Ingredient Supplementation in Professional Football Players Placebo, taurine, Caffeine - Sports Performance, Cognitive Performance During Physical Activity | Not applicable | Completed | Vizja University in Warsaw | 97 | 2026-06-14 | 2026-07-02 |
| Taurine and Nitrate Supplementation on Thermoregulatory in T2DM taurine, Beetroot and taurine, Placebo - Type 2 Diabetes | Not applicable | Not yet recruiting | University of Portsmouth | 18 | 2026-06-01 | 2026-06-18 |
| Taurine for the Prevention and Treatment of Radiation-induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma Taurine - Oral Mucositis (Ulcerative) Due to Radiation, Nasopharyngeal Carcinoma (NPC) | Phase 2 | Recruiting | Sun Yat-sen University | 130 | 2026-05-08 | 2026-10-30 |
| Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity Concurrent Exercise Training, Taurine, Placebo - Obesity (BMI>30) | Not applicable | Active not recruiting | University of Sao Paulo | 44 | 2026-05-01 | 2026-07-28 |
| A Multicenter Clinical Trial Evaluating the Efficacy and Safety of Taurine as an Adjunctive Therapy in Multiple Sclerosis DMTs + taurine, DMTs - Multiple Sclerosis (MS) Relapsing Remitting | Phase 2 | Not yet recruiting | Sichuan Academy of Medical Sciences | 80 | 2026-01-01 | 2025-12-04 |
| Taurine Supplementation in Long COVID Taurine, Placebo - Long COVID | Phase 2 / Phase 3 | Recruiting | University of Alberta | 300 | 2025-11-18 | 2026-09-18 |
| Effects of Energy Drinks on Cardiovascular Endpoints Energy Drink A + Placebo Capsule, Placebo Drink + Moxifloxacin Capsule, Placebo Drink + Caffeine Capsule - Healthy Volunteers, Safety After Oral Intake | Phase 4 | Recruiting | University of the Pacific | 3 | 2025-11-01 | 2025-11-26 |
| Low-Dose Caffeine and Taurine Effects on Performance Caffeine, taurine, Caffeine + Taurine - Anaerobic Performance Neuromuscular Performance Cognitive Performance | Not applicable | Completed | Ankara University | 32 | 2025-10-15 | 2026-03-12 |
| Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study). resveratrol, quercetin, taurine, whey protein, and inulin, whey protein - Liver Disease Chronic, HEPATITIS C VIRUS CHRONIC INFECTION | Not applicable | Recruiting | University of Guadalajara | 26 | 2025-10-11 | 2026-03-23 |
| Effects of Supplementation on Performance in Football Players Placebo, Taurine and Caffeine, Taurine, Caffeine, and Phosphatidylserine - Physical Performance, Cognitive Performance | Not applicable | Completed | Krzysztof Mizera | 81 | 2025-03-25 | 2026-05-26 |
| Effects of Taurine Supplementation on Repetitive Sprint Performance and Exhaustion Time in College Students Under High-Temperature and High-Humidity Conditions High-Dose Taurine Supplementation (6g), Medium-Dose Taurine Supplementation (4g), Low-Dose Taurine Supplementation (1g) - Exercise Performance in Extreme Environments | Not applicable | Completed | Xiaodong Cheng | 16 | 2024-12-01 | 2025-02-13 |
| Clinical Study of Taurine Combined With Neoadjuvant Chemo-Immunotherapy for Treatment of Locally Advanced Gastric Cancer Taurine, Serplulimab, XELOX regimen - Gastric Cancer | Not applicable | Recruiting | Tang-Du Hospital | 96 | 2024-09-01 | 2026-06-09 |
| Clinical Study of Taurine Combined With Sintilimab and Chemotherapy for Treatment of Advanced Gastric Cancer Taurine, Sintilimab, XELOX regimen - Gastric Cancer | Phase 2 | Unknown | Tang-Du Hospital | 60 | 2023-08-01 | 2023-11-08 |
| Taurine Eye Drops May Prevent the Progression of Cataract Taurine - Cataract | Phase 1 / Phase 2 | Active not recruiting | University Of Anbar | 50 | 2023-07-10 | 2024-12-09 |
| Effect of 4 Weeks Supplementation of a Combination of Vitamin Bs and Taurine on Mental Performance in Healthy Adults Capsules with B vitamins & taurine, Microcrystalline cellulose placebo - Healthy | Not applicable | Completed | Société des Produits Nestlé (SPN) | 45 | 2023-03-08 | 2025-05-15 |
| Metabolic and Molecular Responses Under the Effect of Taurine Supplementation With and Without Multicomponent Training Taurine and Exercise (Tau+Ex), Placebo and Exercise (PL+Ex), Taurine (Tau) - Sarcopenic Obesity | Not applicable | Unknown | University of Sao Paulo | 60 | 2022-07-01 | 2022-06-29 |
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Bipolar Disorder (2) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 2 (2) · Fatigue (2) · Mania (2) · Mental Fatigue (2) · Multiple Sclerosis (2) · Obesity (2) · Post-Acute COVID-19 Syndrome (2) · Stomach Neoplasms (2) · Acute Pain (1) · Burnout, Psychological (1) · Cataract (1) · Chronic Pain (1) · Cognitive Dysfunction (1)
University of Sao Paulo (4) · Vizja University in Warsaw (3) · Tang-Du Hospital (2) · Third Military Medical University (2) · University of Alberta (2) · Ain Shams University (1) · Ankara University (1) · Cambridge Health Alliance (1) · Chinese University of Hong Kong (1) · Daewoong Pharmaceutical Co. LTD. (1) · Hamad Medical Corporation (1) · Hospital de Clinicas de Porto Alegre (1) · Krzysztof Mizera (1) · Maharishi Markendeswar University (Deemed to be University) (1) · Mclean Hospital (1)
China (6) · United States (6) · Brazil (4) · Poland (4) · Canada (2) · Australia (1) · Egypt (1) · France (1) · Germany (1) · Hong Kong (1) · Hungary (1) · India (1) · Iraq (1) · Mexico (1) · Netherlands (1)
Ellen C Freitas, PhD (2) · Lawrence Richer, MD, MSc (2) · Xiaodi Zhao, MD, PhD (2) · Xin Wang, MD, PhD (2) · Yuanyuan Lu, MD, PhD (2) · Alexander PJ Houdijk, MD, PhD (1) · Beatriz D Schaan, PhD (1) · Beth L Murphy, MD, PhD (1) · Dr Colin P O'Donnell, MB,MRCPsych (1) · Ece Mutlu, MD, MS, MBA (1) · Ellen C de Freitas, Doctor (1) · Ellen C de Freitas, Ph.D. (1) · H. Rex Gaskins, PhD (1) · Henry Wong, MBChB (1)
PMID 19638084, PMID 22419935, PMID 22810731, PMID 23194775, PMID 23651760, PMID 24093540, PMID 25311610, PMID 25577300, PMID 26621580, PMID 27835719, PMID 28820468, PMID 29105115, PMID 29779170, PMID 30136291, PMID 30805607, PMID 34255136, PMID 39032786, PMID 41889717, PMID 42245559, PMID 42421135
R01CA204808 (1)