10 completed, 2 unknown, 2 withdrawn, 1 recruiting. 9 Not applicable, 2 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 6, Withdrawn 2, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 1 | Unknown 1 |
Follow Sweetening Agents: new trials by email Literature Review of Sweetening Agents trials Research Report on Sweetening Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Growing Well Study Dietary intake and patterns (including vegetarian, vegan, and dairy-free diets) - Dietary Behaviors, Child Growth and Development | Recruiting | University of Leeds | 1890 | 2026-01-05 | 2026-07-13 | |
| Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh Administration of sugar-free gums sugar-free gums containing 100% Xylitol as sweetener, Administration of sugar-free gums sugar-free gums containing containing a polyols mixture plus a low amount of Xylitol (22%) - Caries | Not applicable | Withdrawn | University of Bern | 2021-08-01 | 2025-09-26 | |
| Impact of Sweeteners on Behaviour, Physiology & Health Sweetener and sweetness enhancer consumption - Eating Behavior | Not applicable | Completed | University of Leeds | 175 | 2021-04-01 | 2024-08-12 |
| Artificial Sweeteners in Breast Milk Artificial sweeteners (acesulfame-potassium, sucralose, saccharine, cyclamate) - Breastfeeding, Diabetes Mellitus | Not applicable | Completed | University of Aarhus | 49 | 2020-11-01 | 2022-11-02 |
| The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients. Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland)., Placebo oral sweetener (Clio tablets, sweetener with a dispenser, Instantina GES, Vienna, Austria)., Preoparative blood laboratory tests - Hypocalcemia, Vitamin D Deficiency | Phase 4 | Unknown | Medical University of Lodz | 100 | 2020-07-01 | 2022-02-08 |
| Transport of Artificial Sweeteners During Pregnancy Acesulfame K, cyclamate, saccharine, aspartame - Pregnancy Related, Diabetes | Not applicable | Completed | University of Aarhus | 35 | 2019-06-01 | 2021-02-24 |
| Effects of Dietary Interventions on Serum and Macrophage Atherogenicity monosaccharides, Disaccharides, Amino acids - Dietary Habits, Serum; Disease | Not applicable | Unknown | Rambam Health Care Campus | 90 | 2016-09-01 | 2016-09-27 |
| Effects of Consuming Artificial Sweeteners and Sugar on Cerebral and Physiological Responses ingestion of a test meal with sweetener, ingestion of a test meal with water - Normal Subjects | Not applicable | Completed | University of Lausanne | 18 | 2016-02-01 | 2017-10-26 |
| Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults sweeteners - Development | Completed | Monell Chemical Senses Center | 82 | 2014-05-01 | 2016-01-06 | |
| Comparison of the Effects of a 12-Week Consumption of Two Carbonated Beverages on Insulin Sensitivity Drink with sweeteners, Drink without sweeteners - Glucose Homeostasis | Not applicable | Completed | Institute For European Expertise in Physiology | 60 | 2012-10-01 | 2017-03-03 |
| SEGATROM: Sensory and Gastrointestinal Impact of Taste Receptor Variants on Human Metabolism and Nutrition sweet block, bitter block, umami-block - Disorder of Glucose Regulation | Not applicable | Completed | German Institute of Human Nutrition | 97 | 2011-12-01 | 2020-06-24 |
| The Effect of Artificial Sweeteners on Blood Glucose Response Artificial Sweeteners - Taste Receptors, Nutrient Sensing | Not applicable | Withdrawn | Northumbria University | 2010-11-01 | 2012-05-18 | |
| Effects of Artificial Sweetener on Gastrointestinal (GI) Peptide Secretion Artificial sweeteners; Carbohydrate Sugars, Water - Healthy | Phase 1 | Completed | University Hospital, Basel, Switzerland | 12 | 2008-12-01 | 2009-09-17 |
| Exploring Buckwheat's Glucose Lowering Potential buckwheat, rice crackers, glucose, sugar substitute - Type 2 Diabetes | Completed | St. Boniface Hospital | 24 | 2008-09-01 | 2012-03-21 | |
| The Effect of Methylphenidate on Decision-making Ability of Attention Deficit Hyperactivity Disorder (ADHD) Adults methylphenidate, sweetener pill - Attention Deficit Hyperactivity Disorder | Phase 1 | Completed | Shalvata Mental Health Center | 58 | 2008-01-01 | 2009-12-30 |
Diabetes Mellitus (2) · Feeding Behavior (2) · Atherosclerosis (1) · Attention Deficit Disorder with Hyperactivity (1) · Breast Feeding (1) · Diabetes Mellitus, Type 2 (1) · Disease (1) · Food Preferences (1) · Hoarseness (1) · Hypocalcemia (1) · Hypoparathyroidism (1) · Insulin Resistance (1) · Motor Activity (1) · Overweight (1) · Pain, Postoperative (1)
University of Aarhus (2) · University of Leeds (2) · German Institute of Human Nutrition (1) · Institute For European Expertise in Physiology (1) · Medical University of Lodz (1) · Monell Chemical Senses Center (1) · Northumbria University (1) · Rambam Health Care Campus (1) · Shalvata Mental Health Center (1) · St. Boniface Hospital (1) · University Hospital, Basel, Switzerland (1) · University of Bern (1) · University of Lausanne (1)
Denmark (3) · United Kingdom (3) · France (2) · Israel (2) · Canada (1) · Germany (1) · Poland (1) · Russia (1) · Spain (1) · Switzerland (1)
Andreas FH Peiffer, Prof (1) · Anna Grzegory, MD (1) · Christoph Beglinger, MD (1) · Diane E Threapleton, PhD (1) · Fabrice Bonnet, MD, PhD (1) · Guglielmo Campus (1) · Janet E Cade, PhD (1) · Julie A Mennella, PhD (1) · Luc Tappy, Professor (1) · Nerys M Astbury, PhD (1) · Per Ovesen, DMSc (1) · Peter C Zahradka, PhD (1) · Tony Hayek, Prof. (1) · Ziv Carmel, MD (1)
PMID 26721819, PMID 26959710, PMID 29982723, PMID 34863260, PMID 36564114, PMID 36857956